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We present and compare two different optimal control approaches applied to SEIR models in epidemiology, which allow us to obtain some policies for controlling the spread of an epidemic. The first approach uses Dynamic Programming to…

Optimization and Control · Mathematics 2024-05-06 Simone Cacace , Alessio Oliviero

We consider the problem of controlling the propagation of an epidemic outbreak in an arbitrary contact network by distributing vaccination resources throughout the network. We analyze a networked version of the…

Social and Information Networks · Computer Science 2013-03-19 Victor M. Preciado , Michael Zargham , Chinwendu Enyioha , Ali Jadbabaie , George Pappas

We introduce a general system of ordinary differential equations that includes some classical and recent models for the epidemic spread in a closed population without vital dynamic in a finite time horizon. The model is vectorial, in the…

Optimization and Control · Mathematics 2023-06-21 Lorenzo Freddi

An ordinary differential model is proposed to understand the role of egg quiescence on the efficacy of releasing Wolbachia-infected mosquitoes to control arbovirus transmission. The model admits up to five equilibrium points and four…

Populations and Evolution · Quantitative Biology 2025-07-17 Luís E. S. Lopes , Cláudia P. Ferreira

Predicting the spread of vector-borne diseases in response to incursions requires knowledge of both host and vector demographics in advance of an outbreak. Whereas host population data is typically available, for novel disease introductions…

Populations and Evolution · Quantitative Biology 2015-06-02 Chris Jewell , Richard Brown

This paper analyses the optimal control of infectious disease propagation using a classic susceptible-infected-recovered (SIR) model characterised by permanent immunity and the absence of available vaccines. The control is performed over a…

Optimization and Control · Mathematics 2024-06-12 Rocío Balderrama , Mariana Inés Prieto , Constanza Sánchez de la Vega , Federico Vazquez

Wolbachia infection in Anopheles albimanus mosquitoes can render mosquitoes less capable of spreading malaria. We develop and analyze an ordinary differential equation model to evaluate the effectiveness of Wolbachia-based vector control…

Populations and Evolution · Quantitative Biology 2023-03-10 Daniela Florez , Alyssa Young , Kerlly J. Bernabe , James M. Hyman , Zhuolin Qu

In this paper, we study an optimal control problem of a communicable disease in a prison population. In order to control the spread of the disease inside a prison, we consider an active case-finding strategy, consisting on screening a…

Optimization and Control · Mathematics 2020-11-06 Pedro Gajardo , Victor Riquelme , Diego Vicencio

This work focuses on feedback control strategies for applying the sterile insect technique (SIT) to eliminate pest populations. The presentation is centered on the case of mosquito populations, but most of the results can be extended to…

Analysis of PDEs · Mathematics 2025-12-03 Kala Agbo Bidi , Luís Almeida , Jean-Michel Coron

Sterile insect technique has been successfully applied in the control of agricultural pests, however, it has a limited ability to control mosquitoes. A promising alternative approach is Trojan Y Chromosome strategy, which works by…

Populations and Evolution · Quantitative Biology 2022-05-31 Jingjing Lyu , Musong Gu , Sheng Wang

In this paper we introduce an approach to the management of infectious disease diffusion through the formulation of a controlled compartmental SVIR (Susceptible-Vaccinated-Infected-Recovered) model. We consider a cost functional…

Optimization and Control · Mathematics 2023-11-28 Alessandro Ramponiand M. Elisabetta Tessitore

We analyze an epidemiological model to evaluate the effectiveness of multiple means of control in malaria-endemic areas. The mathematical model consists of a system of several ordinary differential equations, and is based on a…

Populations and Evolution · Quantitative Biology 2023-06-28 Jean Claude Kamgang , Christopher Thron

The introduction of Wolbachia-carrying mosquitoes into the population has recently been proposed as an alternative strategy against dengue. Although laboratory experiments have shown that the Wolbachia bacterium can reduce the levels of…

Populations and Evolution · Quantitative Biology 2017-11-13 Meksianis Z. Ndii

We propose a mathematical model for the transmission dynamics of some strains of the bacterium Vibrio cholerae, responsible for the cholera disease in humans. We prove that, when the basic reproduction number is equal to one, a…

Optimization and Control · Mathematics 2020-06-16 Ana P. Lemos-Paiao , Cristiana J. Silva , Delfim F. M. Torres , Ezio Venturino

This study focuses on optimizing species release $S_2$ to control species population $S_1$ through impulsive release strategies. We investigate the conditions required to remove species $S_1$, which is equivalent to the establishment of…

Optimization and Control · Mathematics 2026-02-09 Jéssica C. S. Alves , Sergio M. Oliva , Christian E. Schaerer

In this paper, we study a novel control method for a generalized SIS epidemic process. In particular, we use predictive control to design optimal protective resource distribution strategies which balance the need to eliminate the epidemic…

Optimization and Control · Mathematics 2018-08-17 Nicholas J. Watkins , George J. Pappas

The control of the spread of dengue fever by introduction of the intracellular parasitic bacterium Wolbachia in populations of the vector Aedes aegypti, is presently one of the most promising tools for eliminating dengue, in the absence of…

Quantitative Methods · Quantitative Biology 2020-10-02 Pierre-Alexandre J. Bliman , M. Soledad Aronna , Flávio C. Coelho , Moacyr A. H. B. da Silva

We study an optimal control problem where the objective is to find the best vaccine allocation during an epidemic outbreak. The epidemic dynamics is described by an age-structured SIR model with nonlocal interactions. Both the infection and…

Optimization and Control · Mathematics 2026-05-19 Luís Almeida , Romain Ducasse , Elisa Paparelli

Avian Spirochaetosis is an acute endemic tick-borne disease of birds, caused by Borrelia anserins, a species of Borrelia bacteria. In this paper, we present a compartmental Mathematical model of the disease for the bird population and Tick…

Optimization and Control · Mathematics 2018-02-13 Joy I. Uwakwe , Simeon C. Inyama , Blessing O. Emerenini

In this paper, we have studied epidemiological models for Ebola infection using nonlinear ordinary differential equations and optimal control theory. We considered optimal control analysis of SIR and SEIR models for the deadly Ebola…

Dynamical Systems · Mathematics 2019-08-23 E. Okyere , J. D. Ankamah , A. K. Hunkpe , D. Mensah
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