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Whole Slide Imaging (WSI) is a cornerstone of digital pathology, offering detailed insights critical for diagnosis and research. Yet, the gigapixel size of WSIs imposes significant computational challenges, limiting their practical utility.…

Image and Video Processing · Electrical Eng. & Systems 2024-11-15 Ravi Kant Gupta , Shounak Das , Amit Sethi

Extracting rich phenotype information, such as cell density and arrangement, from whole slide histology images (WSIs), requires analysis of large field of view, i.e more contexual information. This can be achieved through analyzing the…

Computer Vision and Pattern Recognition · Computer Science 2022-03-30 Saarthak Kapse , Srijan Das , Prateek Prasanna

This paper studies the problem of pre-training for small models, which is essential for many mobile devices. Current state-of-the-art methods on this problem transfer the representational knowledge of a large network (as a Teacher) into a…

Computer Vision and Pattern Recognition · Computer Science 2024-06-18 Mingsheng Li , Lin Zhang , Mingzhen Zhu , Zilong Huang , Gang Yu , Jiayuan Fan , Tao Chen

Whole-slide images (WSIs) contain tissue information distributed across multiple magnification levels, yet most self-supervised methods treat these scales as independent views. This separation prevents models from learning representations…

Multiple Instance Learning (MIL) for whole slide image (WSI) analysis in computational pathology often neglects instance-level learning as supervision is typically provided only at the bag level, hindering the integrated consideration of…

Computer Vision and Pattern Recognition · Computer Science 2025-09-26 Shuyang Wu , Yifu Qiu , Ines P. Nearchou , Sandrine Prost , Jonathan A. Fallowfield , Hideki Ueno , Hitoshi Tsuda , David J. Harrison , Hakan Bilen , Timothy J. Kendall

Deep learning has shown strong potential in cancer classification from whole-slide images (WSIs), but the need for extensive expert annotations often limits its success. Annotation-free approaches, such as multiple instance learning (MIL)…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Willmer Rafell Quinones Robles , Sakonporn Noree , Jongwoo Kim , Young Sin Ko , Bryan Wong , Mun Yong Yi

A crucial step to efficiently integrate Whole Slide Images (WSIs) in computational pathology is assigning a single high-quality feature vector, i.e., one embedding, to each WSI. With the existence of many pre-trained deep neural networks…

Image and Video Processing · Electrical Eng. & Systems 2025-05-22 Sobhan Hemati , Ghazal Alabtah , Saghir Alfasly , H. R. Tizhoosh

Whole-slide image analysis via the means of computational pathology often relies on processing tessellated gigapixel images with only slide-level labels available. Applying multiple instance learning-based methods or transformer models is…

Computer Vision and Pattern Recognition · Computer Science 2023-10-20 Joshua Butke , Noriaki Hashimoto , Ichiro Takeuchi , Hiroaki Miyoshi , Koichi Ohshima , Jun Sakuma

Whole slide images (WSIs) are massive digital pathology files illustrating intricate tissue structures. Selecting a small, representative subset of patches from each WSI is essential yet challenging. Therefore, following the "Divide &…

Computer Vision and Pattern Recognition · Computer Science 2023-11-17 Abubakr Shafique , Saghir Alfasly , Areej Alsaafin , Peyman Nejat , Jibran A. Khan , H. R. Tizhoosh

Pathology foundation models (PFMs) have emerged as a core approach for learning transferable representations from whole slide images (WSIs), and they are typically benchmarked through downstream clinical endpoints. While such task level…

Computer Vision and Pattern Recognition · Computer Science 2026-05-26 Bokai Zhao , Yiyang Zhang , Yuanchi Zhu , Hanqing Chao , Long Bai , Tai Ma , Minfeng Xu , Ming Song , Tianzi Jiang

Histopathological whole slide images (WSIs) classification has become a foundation task in medical microscopic imaging processing. Prevailing approaches involve learning WSIs as instance-bag representations, emphasizing significant…

Computer Vision and Pattern Recognition · Computer Science 2024-03-13 Jiawen Li , Yuxuan Chen , Hongbo Chu , Qiehe Sun , Tian Guan , Anjia Han , Yonghong He

The landscape of self-supervised learning (SSL) is currently dominated by generative approaches (e.g., MAE) that reconstruct raw low-level data, and predictive approaches (e.g., I-JEPA) that predict high-level abstract embeddings. While…

Computer Vision and Pattern Recognition · Computer Science 2026-03-17 Scott C. Lowe , Anthony Fuller , Sageev Oore , Evan Shelhamer , Graham W. Taylor

Existing knowledge distillation methods mostly focus on distillation of teacher's prediction and intermediate activation. However, the structured representation, which arguably is one of the most critical ingredients of deep models, is…

Computer Vision and Pattern Recognition · Computer Science 2024-07-16 Jing Yang , Xiatian Zhu , Adrian Bulat , Brais Martinez , Georgios Tzimiropoulos

Self-distillation bootstraps large language models (LLMs) by training on their own generations. However, existing methods either rely on external signals to curate self-generated outputs (e.g., correctness filtering, execution feedback, and…

Computation and Language · Computer Science 2026-05-22 Guangya Hao , Yitong Shang , Yunbo Long , Zhuokai Zhao , Hanxue Liang

Representation learning for Whole Slide Images (WSIs) is pivotal in developing image-based systems to achieve higher precision in diagnostic pathology. We propose a two-stage framework for WSI representation learning. We sample relevant…

Image and Video Processing · Electrical Eng. & Systems 2020-04-20 Mohammed Adnan , Shivam Kalra , Hamid R. Tizhoosh

Automated whole slide image (WSI) tagging has become a growing demand due to the increasing volume and diversity of WSIs collected nowadays in histopathology. Various methods have been studied to classify WSIs with single tags but none of…

Computer Vision and Pattern Recognition · Computer Science 2019-07-05 Weijian Li , Viet-Duy Nguyen , Haofu Liao , Matt Wilder , Ke Cheng , Jiebo Luo

Although lip-to-speech synthesis (L2S) has achieved significant progress in recent years, current state-of-the-art methods typically rely on intermediate representations such as mel-spectrograms or discrete self-supervised learning (SSL)…

Audio and Speech Processing · Electrical Eng. & Systems 2026-02-13 Yifan Liang , Andong Li , Kang Yang , Guochen Yu , Fangkun Liu , Lingling Dai , Xiaodong Li , Chengshi Zheng

We developed a software pipeline for quality control (QC) of histopathology whole slide images (WSIs) that segments various regions, such as blurs of different levels, tissue regions, tissue folds, and pen marks. Given the necessity and…

Image and Video Processing · Electrical Eng. & Systems 2025-06-17 Abhijeet Patil , Garima Jain , Harsh Diwakar , Jay Sawant , Tripti Bameta , Swapnil Rane , Amit Sethi

Dataset distillation aims to compress information from a large-scale original dataset to a new compact dataset while striving to preserve the utmost degree of the original data informational essence. Previous studies have predominantly…

Computer Vision and Pattern Recognition · Computer Science 2024-04-12 Muxin Zhou , Zeyuan Yin , Shitong Shao , Zhiqiang Shen

Recent advancements in deep learning have shifted the development of brain imaging analysis. However, several challenges remain, such as heterogeneity, individual variations, and the contradiction between the high dimensionality and small…

Computer Vision and Pattern Recognition · Computer Science 2024-07-24 Yanwu Yang , Hairui Chen , Jiesi Hu , Xutao Guo , Ting Ma