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We present a novel, computationally efficient approach to accelerate quantum optimal control calculations of large multi-qubit systems used in a variety of quantum computing applications. By leveraging the intrinsic symmetry of finite…

Quantum Physics · Physics 2023-10-05 Xian Wang , Mahmut Sait Okyay , Anshuman Kumar , Bryan M. Wong

Recent technological developments have focused the interest of the quantum computing community on investigating how near-term devices could outperform classical computers for practical applications. A central question that remains open is…

Quantum Physics · Physics 2021-11-24 Daniel Stilck Franca , Raul Garcia-Patron

The maximum-cut problem is one of the fundamental problems in combinatorial optimization. With the advent of quantum computers, both the maximum-cut and the equivalent quadratic unconstrained binary optimization problem have experienced…

Optimization and Control · Mathematics 2022-02-07 Daniel Rehfeldt , Thorsten Koch , Yuji Shinano

Quantum approaches to combinatorial optimization problems (COPs) are often limited by the resource demands of Quadratic Unconstrained Binary Optimization (QUBO) encodings, which enlarge circuits through penalty terms and increase qubit and…

Quantum Physics · Physics 2025-11-25 Frederik Koch , Shahram Panahiyan , Rick Mukherjee , Joseph Doetsch , Dieter Jaksch

In the wake of quantum computing advancements and quantum algorithmic progress, quantum algorithms are increasingly being employed to address a myriad of combinatorial optimization problems. Among these, the Independent Domination Problem…

Quantum Physics · Physics 2024-12-31 Haoqian Pan , Changhong Lu

We present a heuristic algorithm designed to solve Quadratic Unconstrained Binary Optimization (QUBO) problems efficiently. The algorithm, referred to as IC-D2S, leverages a hybrid approach using Ising and classical machines to address very…

Hardware Architecture · Computer Science 2025-02-20 Armin Abdollahi , Mehdi Kamal , Massoud Pedram

Quantum algorithms can deliver asymptotic speedups over their classical counterparts. However, there are few cases where a substantial quantum speedup has been worked out in detail for reasonably-sized problems, when compared with the best…

Quantum Physics · Physics 2019-07-24 Earl Campbell , Ankur Khurana , Ashley Montanaro

Variational quantum algorithms are proposed to solve relevant computational problems on near term quantum devices. Popular versions are variational quantum eigensolvers and quantum ap- proximate optimization algorithms that solve ground…

Quantum Physics · Physics 2022-04-15 Lennart Bittel , Martin Kliesch

A range of quantum algorithms, especially those leveraging variational parameterization and circuit-based optimization, are being studied as alternatives for solving classically intractable combinatorial optimization problems (COPs).…

Quantum Physics · Physics 2025-06-18 Monit Sharma , Hoong Chuin Lau

Adiabatic quantum computing is implemented on specialized hardware using the heuristics of the quantum annealing algorithm. This setup requires the addressed problems to be formatted as discrete quadratic functions without constraints and…

Computer Science and Game Theory · Computer Science 2024-01-23 Olga Okrut , Keith Cannon , Kareem H. El-Safty , Nada Elsokkary , Faisal Shah Khan

Quantum annealing is a heuristic algorithm that solves combinatorial optimization problems, and D-Wave Systems Inc. has developed hardware implementation of this algorithm. However, in general, we cannot embed all the logical variables of a…

Quantum Physics · Physics 2019-04-01 Shuntaro Okada , Masayuki Ohzeki , Masayoshi Terabe , Shinichiro Taguchi

Designing quantum algorithms with a speedup over their classical analogs is a central challenge in quantum information science. Motivated by recent experimental observations of a superlinear quantum speedup in solving the Maximum…

Quantum Approximate Optimization Algorithm (QAOA) can be used to solve quadratic unconstrained binary optimization (QUBO) problems. However, the size of the solvable problem is limited by the number of qubits. To leverage noisy…

Quantum Physics · Physics 2025-06-10 Wending Zhao , Gaoxiang Tang

The peptide-protein docking problem is an important problem in structural biology that facilitates rational and efficient drug design. In this work, we explore modeling and solving this problem with the quantum-amenable quadratic…

The bin packing is a well-known NP-Hard problem in the domain of artificial intelligence, posing significant challenges in finding efficient solutions. Conversely, recent advancements in quantum technologies have shown promising potential…

Quantum Physics · Physics 2024-01-17 Lorenzo Cellini , Antonio Macaluso , Michele Lombardi

Constraints make hard optimization problems even harder to solve on quantum devices because they are implemented with large energy penalties and additional qubit overhead. The parity mapping, which has been introduced as an alternative to…

Quantum Physics · Physics 2023-03-20 Maike Drieb-Schön , Kilian Ender , Younes Javanmard , Wolfgang Lechner

Quadratic Unconstrained Binary Optimization (QUBO) is a standard NP-hard optimization problem. Recently, it has gained renewed interest through quantum computing, as QUBOs directly reduce to the Ising model, on which quantum annealing…

Quantum Physics · Physics 2026-03-16 Katalin Friedl , Levente Gegő , László Kabódi , Viktória Nemkin

We propose and evaluate a quantum-inspired algorithm for solving Quadratic Unconstrained Binary Optimization (QUBO) problems, which are mathematically equivalent to finding ground states of Ising spin-glass Hamiltonians. The algorithm…

Artificial Intelligence · Computer Science 2025-10-24 Max B. Zhao , Fei Li

Training Support Vector Machines (SVMs) can be formulated as a QUBO problem, enabling the use of quantum annealing for model optimization. In this work, we study how the number of qubits - linked to the discretization level of dual weights…

Machine Learning · Computer Science 2025-10-31 Sascha Mücke

In this paper, we introduce three QUBO (Quadratic Unconstrained Binary Optimization) relaxations for the sparsest $k$-subgraph (SkS) problem: a quadratic penalty relaxation, a Lagrangian relaxation, and an augmented Lagrangian relaxation.…

Optimization and Control · Mathematics 2025-09-11 Omkar Bihani , Roman Kužel , Janez Povh , Dunja Pucher