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Generalisability and transportability of clinical prediction models (CPMs) refer to their ability to maintain predictive performance when applied to new populations. While CPMs may show good generalisability or transportability to a…

Methodology · Statistics 2024-12-06 Kritchavat Ploddi , Matthew Sperrin , Glen P. Martin , Maurice M. O'Connell

Electronic Health Records (EHRs) and routine documentation practices play a vital role in patients' daily care, providing a holistic record of health, diagnoses, and treatment. However, complex and verbose EHR narratives overload healthcare…

Computation and Language · Computer Science 2025-02-26 Yanjun Gao , Ruizhe Li , Emma Croxford , John Caskey , Brian W Patterson , Matthew Churpek , Timothy Miller , Dmitriy Dligach , Majid Afshar

The increasing amount of published scholarly articles, exceeding 2.5 million yearly, raises the challenge for researchers in following scientific progress. Integrating the contributions from scholarly articles into a novel type of cognitive…

Digital Libraries · Computer Science 2024-09-12 Gollam Rabby , Sören Auer , Jennifer D'Souza , Allard Oelen

As machine learning (ML)-based decision support tools proliferate in clinical practice, understanding how clinicians integrate personalized ML predictions alongside randomized controlled trial (RCT) evidence is critical. We designed a…

Human-Computer Interaction · Computer Science 2026-05-19 Zeshan Hussain , Barbara D. Lam , Fernando A. Acosta-Perez , Irbaz Bin Riaz , Maia Jacobs , Andrew J. Yee , David Sontag

Intensive Care Units (ICU) require comprehensive patient data integration for enhanced clinical outcome predictions, crucial for assessing patient conditions. Recent deep learning advances have utilized patient time series data, and fusion…

Machine Learning · Computer Science 2023-11-14 Samyak Jain , Manuel Burger , Gunnar Rätsch , Rita Kuznetsova

Lung cancer is the leading reason behind cancer-related deaths within the world. Early detection of lung nodules is vital for increasing the survival rate of cancer patients. Traditionally, physicians should manually identify the world…

Image and Video Processing · Electrical Eng. & Systems 2023-05-31 Hasan Hejbari Zargar , Saha Hejbari Zargar , Raziye Mehri , Farzane Tajidini

Accurate prediction of treatment outcomes in lung cancer remains challenging due to the sparsity, heterogeneity, and contextual overload of real-world electronic health data. Traditional models often fail to capture semantic information…

Lung cancer is one of the prevalence diseases in the world which cause many deaths. Detecting early stages of lung cancer is so necessary. So, modeling and simulating some intelligent medical systems is an essential which can help…

Image and Video Processing · Electrical Eng. & Systems 2023-12-07 Ehsan Sadeghi Pour , Mahdi Esmaeili

Interventional cancer clinical trials are generally too restrictive, and some patients are often excluded on the basis of comorbidity, past or concomitant treatments, or the fact that they are over a certain age. The efficacy and safety of…

Computation and Language · Computer Science 2018-07-26 Aurelia Bustos , Antonio Pertusa

Biomedical knowledge graphs (KGs) are widely used across research and translational settings, yet their design decisions and implementation are often opaque. Unlike ontologies that more frequently adhere to established creation principles,…

We introduce a new computer aided detection and diagnosis system for lung cancer screening with low-dose CT scans that produces meaningful probability assessments. Our system is based entirely on 3D convolutional neural networks and…

Computer Vision and Pattern Recognition · Computer Science 2020-01-22 Onur Ozdemir , Rebecca L. Russell , Andrew A. Berlin

Artificial intelligence (AI) is reshaping modern healthcare by advancing disease diagnosis, treatment decision-making, and biomedical research. Among AI technologies, large language models (LLMs) have become especially impactful, enabling…

Artificial Intelligence · Computer Science 2025-11-18 Zhengda Wang , Daqian Shi , Jingyi Zhao , Xiaolei Diao , Xiongfeng Tang , Yanguo Qin

The paper introduces ExKG-LLM, a framework designed to automate the expansion of cognitive neuroscience knowledge graphs (CNKG) using large language models (LLMs). It addresses limitations in existing tools by enhancing accuracy,…

Artificial Intelligence · Computer Science 2025-07-09 Ali Sarabadani , Kheirolah Rahsepar Fard , Hamid Dalvand

The recent development of high-throughput sequencing creates a large collection of multi-omics data, which enables researchers to better investigate cancer molecular profiles and cancer taxonomy based on molecular subtypes. Integrating…

Genomics · Quantitative Biology 2024-01-25 Bingjun Li , Sheida Nabavi

The rapid expansion of publicly-available medical data presents a challenge for clinicians and researchers alike, increasing the gap between the volume of scientific literature and its applications. The steady growth of studies and findings…

Artificial Intelligence · Computer Science 2025-08-06 Taine J. Elliott , Stephen P. Levitt , Ken Nixon , Martin Bekker

Objective: The majority of detailed patient information in real-world data (RWD) is only consistently available in free-text clinical documents. Manual curation is expensive and time-consuming. Developing natural language processing (NLP)…

In the medical domain, the continuous stream of scientific research contains contradictory results supported by arguments and counter-arguments. As medical expertise occurs at different levels, part of the human agents have difficulties to…

Artificial Intelligence · Computer Science 2016-07-28 Adrian Groza , Oana Popa

Drug repurposing is often framed as a candidate identification task, but existing approaches provide limited guidance for distinguishing biologically plausible candidates from historically well-connected ones. Here we introduce DrugKLM, a…

Feature selection in Knowledge Graphs (KGs) are increasingly utilized in diverse domains, including biomedical research, Natural Language Processing (NLP), and personalized recommendation systems. This paper delves into the methodologies…

Machine Learning · Computer Science 2024-06-24 Sisi Shao , Pedro Henrique Ribeiro , Christina Ramirez , Jason H. Moore