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This paper studies Clinical Intelligent Decision Support Systems (CIDSSs) for lung cancer segmentation, which are based on deep neural nets. A new interactive CIDSS is proposed and compared with previous approaches. Addition-ally, the…

Image and Video Processing · Electrical Eng. & Systems 2024-08-28 Volodymyr Sydorskyi

Mapping clinical documents to standardised clinical vocabularies is an important task, as it provides structured data for information retrieval and analysis, which is essential to clinical research, hospital administration and improving…

Computation and Language · Computer Science 2025-09-15 Mingyang Li , Viktor Schlegel , Tingting Mu , Warren Del-Pinto , Goran Nenadic

Recent years have seen great advancements in the development of deep learning models for histopathology image analysis in digital pathology applications, evidenced by the increasingly common deployment of these models in both research and…

Image and Video Processing · Electrical Eng. & Systems 2022-08-09 Veena Kaustaban , Qinle Ba , Ipshita Bhattacharya , Nahil Sobh , Satarupa Mukherjee , Jim Martin , Mohammad Saleh Miri , Christoph Guetter , Amal Chaturvedi

Clinical reasoning refers to the cognitive process that physicians employ in evaluating and managing patients. This process typically involves suggesting necessary examinations, diagnosing patients' diseases, and deciding on appropriate…

Computation and Language · Computer Science 2024-06-11 Jiageng WU , Xian Wu , Jie Yang

The most deadly and life-threatening disease in the world is lung cancer. Though early diagnosis and accurate treatment are necessary for lowering the lung cancer mortality rate. A computerized tomography (CT) scan-based image is one of the…

Image and Video Processing · Electrical Eng. & Systems 2023-04-12 Muntasir Mamun , Md Ishtyaq Mahmud , Mahabuba Meherin , Ahmed Abdelgawad

Machine-learning-assisted cancer subtyping is a promising avenue in digital pathology. Cancer subtyping models, however, require careful training using expert annotations so that they can be inferred with a degree of known certainty (or…

Using natural language processing tools, we investigate the differences of recommendations in medical guidelines for the same decision problem -- breast cancer screening. We show that these differences arise from knowledge brought to the…

Information Retrieval · Computer Science 2020-07-22 Hossein Hematialam , Luciana Garbayo , Seethalakshmi Gopalakrishnan , Wlodek Zadrozny

Question answering is a natural language understanding task that involves reasoning over both explicit context, and unstated relevant domain knowledge. Despite the high cost of training, large language models (LLMs) -- the backbone of most…

Computation and Language · Computer Science 2025-04-24 Laura Cabello , Carmen Martin-Turrero , Uchenna Akujuobi , Anders Søgaard , Carlos Bobed

An increasing number of public datasets have shown a marked impact on automated organ segmentation and tumor detection. However, due to the small size and partially labeled problem of each dataset, as well as a limited investigation of…

Image and Video Processing · Electrical Eng. & Systems 2024-06-27 Jie Liu , Yixiao Zhang , Jie-Neng Chen , Junfei Xiao , Yongyi Lu , Bennett A. Landman , Yixuan Yuan , Alan Yuille , Yucheng Tang , Zongwei Zhou

Machine learning models have utilized semantic features, deep features, or both to assess lung nodule malignancy. However, their reliance on manual annotation during inference, limited interpretability, and sensitivity to imaging variations…

Computer Vision and Pattern Recognition · Computer Science 2025-11-04 Luoting Zhuang , Seyed Mohammad Hossein Tabatabaei , Ramin Salehi-Rad , Linh M. Tran , Denise R. Aberle , Ashley E. Prosper , William Hsu

Colorectal cancer (CRC) grading is typically carried out by assessing the degree of gland formation within histology images. To do this, it is important to consider the overall tissue micro-environment by assessing the cell-level…

Image and Video Processing · Electrical Eng. & Systems 2019-09-04 Yanning Zhou , Simon Graham , Navid Alemi Koohbanani , Muhammad Shaban , Pheng-Ann Heng , Nasir Rajpoot

Virtually every sector of society is experiencing a dramatic growth in the volume of unstructured textual data that is generated and published, from news and social media online interactions, through open access scholarly communications and…

Computation and Language · Computer Science 2026-03-30 Vanni Zavarella

Personalized cancer treatment requires a thorough understanding of complex interactions between drugs and cancer cell lines in varying genetic and molecular contexts. To address this, high-throughput screening has been used to generate…

Machine Learning · Computer Science 2023-07-03 Vishal Dey , Xia Ning

Clinical tasks such as diagnosis and treatment require strong decision-making abilities, highlighting the importance of rigorous evaluation benchmarks to assess the reliability of large language models (LLMs). In this work, we introduce a…

Computation and Language · Computer Science 2025-07-04 Running Yang , Wenlong Deng , Minghui Chen , Yuyin Zhou , Xiaoxiao Li

Large Language Models (LMs) are known to encode world knowledge in their parameters as they pretrain on a vast amount of web corpus, which is often utilized for performing knowledge-dependent downstream tasks such as question answering,…

Computation and Language · Computer Science 2022-05-25 Joel Jang , Seonghyeon Ye , Sohee Yang , Joongbo Shin , Janghoon Han , Gyeonghun Kim , Stanley Jungkyu Choi , Minjoon Seo

The application of AI in oncology has been limited by its reliance on large, annotated datasets and the need for retraining models for domain-specific diagnostic tasks. Taking heed of these limitations, we investigated in-context learning…

Image and Video Processing · Electrical Eng. & Systems 2025-05-15 Mobina Shrestha , Bishwas Mandal , Vishal Mandal , Asis Shrestha

Clinical diagnosis requires answers that are accurate, verifiable, and explicitly grounded in official guidelines. While large language models excel at natural language processing, their tendency to hallucinate undermines their utility in…

Artificial Intelligence · Computer Science 2026-05-29 Navapat Nananukul , Mayank Kejriwal

Convolutional neural networks (CNNs) have shown great promise in improving computer aided detection (CADe). From classifying tumors found via mammography as benign or malignant to automated detection of colorectal polyps in CT colonography,…

Computer Vision and Pattern Recognition · Computer Science 2019-07-30 Hunter Park , Connor Monahan

Large language models (LLMs) have shown strong knowledge reserves and task-solving capabilities, but still face the challenge of severe hallucination, hindering their practical application. Though scientific theories and rules can…

Computation and Language · Computer Science 2026-04-09 Maotian Ma , Zheni Zeng , Zhenghao Liu , Yukun Yan

The study explores Artificial Intelligence (AI) powered modeling to predict the evolution of cancer tumor cells in mice under different forms of treatment. The AI models are analyzed against varying ambient and systemic parameters, e.g.…

Biological Physics · Physics 2024-08-12 Amit K Chattopadhyay , Aimee Pascaline N Unkundiye , Gillian Pearce , Steven Russell
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