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Supervised deep learning requires a large amount of training samples with annotations (e.g. label class for classification task, pixel- or voxel-wised label map for segmentation tasks), which are expensive and time-consuming to obtain.…

Computer Vision and Pattern Recognition · Computer Science 2020-04-14 Yuanhan Mo , Shuo Wang , Chengliang Dai , Rui Zhou , Zhongzhao Teng , Wenjia Bai , Yike Guo

Optimization in machine learning, both theoretical and applied, is presently dominated by first-order gradient methods such as stochastic gradient descent. Second-order optimization methods, that involve second derivatives and/or second…

Machine Learning · Computer Science 2021-03-08 Rohan Anil , Vineet Gupta , Tomer Koren , Kevin Regan , Yoram Singer

Employing large antenna arrays and utilizing large bandwidth have the potential of bringing very high data rates to future wireless communication systems. However, this brings the system into the near-field regime and also makes the…

Information Theory · Computer Science 2023-01-03 Yu Zhang , Ahmed Alkhateeb

Proteins are essential for life, and their structure determines their function. The protein secondary structure is formed by the folding of the protein primary structure, and the protein tertiary structure is formed by the bending and…

Biomolecules · Quantitative Biology 2024-03-11 Yanlin Zhou , Kai Tan , Xinyu Shen , Zheng He , Haotian Zheng

While artificial intelligence has made remarkable strides in revealing the relationship between biological macromolecules' primary sequence and tertiary structure, designing RNA sequences based on specified tertiary structures remains…

Biomolecules · Quantitative Biology 2024-03-08 Cheng Tan , Yijie Zhang , Zhangyang Gao , Bozhen Hu , Siyuan Li , Zicheng Liu , Stan Z. Li

We propose a probabilistic framework for modelling and exploring the latent structure of relational data. Given feature information for the nodes in a network, the scalable deep generative relational model (SDREM) builds a deep network…

Machine Learning · Statistics 2019-11-06 Xuhui Fan , Bin Li , Scott Anthony Sisson , Caoyuan Li , Ling Chen

Transformer models have achieved state-of-the-art results across a diverse range of domains. However, concern over the cost of training the attention mechanism to learn complex dependencies between distant inputs continues to grow. In…

The folding of RNA and DNA strands plays crucial roles in biological systems and bionanotechnology. However, studying these processes with high-resolution numerical models is beyond current computational capabilities due to the timescales…

Soft Condensed Matter · Physics 2024-02-07 F. Tosti Guerra , E. Poppleton , P. Šulc , L. Rovigatti

Long non-coding RNA, microRNA, and messenger RNA enable key regulations of various biological processes through a variety of diverse interaction mechanisms. Identifying the interactions and cross-talk between these heterogeneous RNA classes…

Molecular Networks · Quantitative Biology 2020-12-10 Nhat Tran , Jean Gao

This work presents an analysis of the effectiveness of using standard shallow feed-forward networks to mimic the behavior of the attention mechanism in the original Transformer model, a state-of-the-art architecture for sequence-to-sequence…

Computation and Language · Computer Science 2024-02-06 Vukasin Bozic , Danilo Dordevic , Daniele Coppola , Joseph Thommes , Sidak Pal Singh

This paper presents SANA-1.5, a linear Diffusion Transformer for efficient scaling in text-to-image generation. Building upon SANA-1.0, we introduce three key innovations: (1) Efficient Training Scaling: A depth-growth paradigm that enables…

Computer Vision and Pattern Recognition · Computer Science 2025-05-20 Enze Xie , Junsong Chen , Yuyang Zhao , Jincheng Yu , Ligeng Zhu , Chengyue Wu , Yujun Lin , Zhekai Zhang , Muyang Li , Junyu Chen , Han Cai , Bingchen Liu , Daquan Zhou , Song Han

High-dimensional, heterogeneous data with complex feature interactions pose significant challenges for traditional predictive modeling approaches. While Projection to Latent Structures (PLS) remains a popular technique, it struggles to…

Machine Learning · Computer Science 2025-10-21 Farwa Abbas , Hussain Ahmad , Claudia Szabo

Recent architectural developments have enabled recurrent neural networks (RNNs) to reach and even surpass the performance of Transformers on certain sequence modeling tasks. These modern RNNs feature a prominent design pattern: linear…

Standard inference and training with transformer based architectures scale quadratically with input sequence length. This is prohibitively large for a variety of applications especially in web-page translation, query-answering etc.…

Computation and Language · Computer Science 2023-03-20 Lovish Madaan , Srinadh Bhojanapalli , Himanshu Jain , Prateek Jain

Spiking neural networks (SNNs) have made great progress on both performance and efficiency over the last few years,but their unique working pattern makes it hard to train a high-performance low-latency SNN.Thus the development of SNNs still…

Neural and Evolutionary Computing · Computer Science 2022-11-22 Yudong Li , Yunlin Lei , Xu Yang

Convolutional Neural Network (CNN) has gained state-of-the-art results in many pattern recognition and computer vision tasks. However, most of the CNN structures are manually designed by experienced researchers. Therefore, auto- matically…

Neural and Evolutionary Computing · Computer Science 2018-10-26 Guoqiang Zhong , Tao Li , Wenxue Liu , Yang Chen

Deep learning has proven to successfully learn variations in tissue and cell morphology. Training of such models typically relies on expensive manual annotations. Here we conjecture that spatially resolved gene expression, e.i., the…

Quantitative Methods · Quantitative Biology 2023-12-11 Axel Andersson , Gabriele Partel , Leslie Solorzano , Carolina Wählby

The relationship between RNA structure and function has recently attracted interest within the deep learning community, a trend expected to intensify as nucleic acid structure models advance. Despite this momentum, the lack of standardized,…

Biomolecules · Quantitative Biology 2025-10-23 Luis Wyss , Vincent Mallet , Wissam Karroucha , Karsten Borgwardt , Carlos Oliver

Equivariant Graph Neural Networks (EGNNs) have become a widely used approach for modeling 3D atomistic systems. However, mainstream architectures face critical scalability bottlenecks due to the explicit construction of geometric features…

Machine Learning · Computer Science 2026-01-26 Lin Huang , Chengxiang Huang , Ziang Wang , Yiyue Du , Chu Wang , Haocheng Lu , Yunyang Li , Xiaoli Liu , Arthur Jiang , Jia Zhang

Current neural network (NN) models can learn patterns from data points with historical dependence. Specifically, in natural language processing (NLP), sequential learning has transitioned from recurrence-based architectures to…

Machine Learning · Computer Science 2025-04-08 Muhammed Adil Yatkin , Mihkel Korgesaar , Jani Romanoff , Umit Islak , Hasan Kurban
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