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We report the cell biological applications of a recently developed multiphoton fluorescence lifetime imaging microscopy system using a streak camera (StreakFLIM). The system was calibrated with standard fluorophore specimens and was shown…

Cell Behavior · Quantitative Biology 2009-11-10 R. V. Krishnan , Eva Biener , Jian-Hua Zhang , Robert Heckel , Brian Herman

Spectroscopy is an important tool for probing the properties of materials, chemicals and biological samples. We design a practical transmitter-receiver system that exploits entanglement to achieve a provable quantum advantage over all…

Quantum Physics · Physics 2020-11-03 Haowei Shi , Zheshen Zhang , Stefano Pirandola , Quntao Zhuang

Phase-locked ultrashort pulses in the rich terahertz (THz) spectral range have provided key insights into phenomena as diverse as quantum confinement, first-order phase transitions, high-temperature superconductivity, and carrier transport…

Mesoscale and Nanoscale Physics · Physics 2016-04-18 M. Eisele , T. L. Cocker , M. A. Huber , M. Plankl , L. Viti , D. Ercolani , L. Sorba , M. S. Vitiello , R. Huber

Terahertz (THz) waves have been significantly developed in the last fifteen years because of their great potential for applications in industrial and scientific communities1,2. The unique properties of THz waves as transparency for numerous…

Optics · Physics 2015-05-27 F. Blanchard , A. Doi , T. Tanaka , H. Hirori , H. Tanaka , Y. Kadoya , K. Tanaka

THz spectroscopy is an emerging tool for detection of microorganisms and harmful compounds in the food industry, the study of proteins in biomedicine and the development of electron-beam X-ray sources for molecular imaging and lithography.…

The large capacity and robustness of information encoding in the temporal mode of photons is important in quantum information processing, in which characterizing temporal quantum states with high usability and time resolution is essential.…

Terahertz Time-Domain Spectroscopy is a powerful technique for extracting the low-frequency optical properties of materials. However, the optical constants are difficult to determine directly from the experimental transfer function, such…

Optics · Physics 2025-06-02 Kamyar Rashidi , Matthew Y. Sfeir

Two-photon absorption (TPA) fluorescence of biomarkers has been decisive in advancing the fields of biosensing and deep-tissue in vivo imaging of live specimens. However, due to the extremely small TPA cross section and the quadratic…

Optics · Physics 2020-06-25 Tian Li , Fu Li , Charles Altuzarra , Anton Classen , Girish S. Agarwal

How molecules convert light energy to perform a specific transformation is a fundamental question in photophysics. Ultrafast spectroscopy reveals the kinetics associated with electronic energy flow, but little is known about how absorbed…

Transient field-resolved spectroscopy enables studies of ultrafast dynamics in molecules, nanostructures, or solids with sub-cycle resolution, but previous work has so far concentrated on extracting the dielectric response at frequencies…

In the present work, we examine the relevance and proper interpretation of broadband-dielectric and THz-spectroscopy data for the investigation of various types of biological matter. We provide an overview of the rich variety of different…

Soft Condensed Matter · Physics 2025-11-13 Peter Lunkenheimer , Sebastian Emmert , Martin Wolf , Alois Loidl

We present a development of a high precision, tunable far-infrared (terahertz) frequency-domain dielectric spectrometer for studying the dynamics of biomolecules in aqueous solutions in the gigahertz-to-terahertz frequency. As a first…

Biological Physics · Physics 2016-01-20 Deepu K. George , Ali Charkhesht , N. Q. Vinh

Time- and Angle-resolved photoelectron spectroscopy from surfaces can be used to record the dynamics of electrons and holes in condensed matter on ultrafast time scales. However, ultrafast photoemission experiments using extreme-ultraviolet…

Understanding transcription factor dynamics is crucial for unraveling the regulatory mechanisms of gene expression that underpin cellular function and development. Measurements of transcription factor subcellular movements are essential for…

Quantitative Methods · Quantitative Biology 2025-03-20 Sharva V. Hiremath , Etika Goyal , Gregory T. Reeves , Cranos M. Williams

Photoactive proteins absorb light and undergo structural changes that enable them to perform essential biological functions. These proteins are critical for understanding light-induced biological processes, making them important in…

Chemical Physics · Physics 2025-03-28 Sylwia Czach , Jakub Rydzewski , Wiesław Nowak

The sub-bandgap absorption and ultrafast relaxation in a GaAs/ErAs/GaAs heterostructure are reported. The infrared absorption and 1550 nm-excited ultrafast photo-response are studied by Fourier transform infrared (FTIR) spectrometry and…

Materials Science · Physics 2021-03-01 Kedong Zhang , Yiwen Li , Yifeng Ren , Xing Fan , Chen Li , Jianfei Li , Yafei Meng , Yu Deng , Fengqiu Wang , Hong Lu , Yan-Feng Chen

A compact versatile photoacoustic (PA) sensor for trace gas detection is reported. The sensor is based on an integrating sphere as the PA absorption cell with an organ pipe tube attached to increase the sensitivity of the PA sensor. The…

Many linked processes occur concurrently in strongly excited semiconductors, such as interband and intraband absorption, scattering of electrons and holes by the heated lattice, Pauli blocking, bandgap renormalization and the formation of…

Understanding microscopic processes in materials and devices that can be switched by light requires experimental access to dynamics on nanometer length and femtosecond time scales. Here, we introduce ultrafast dark-field electron…

Materials Science · Physics 2021-01-25 Thomas Danz , Till Domröse , Claus Ropers