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We present a diagrammatic method to build up sophisticated cellular automata (CAs) as models of complex physical systems. The diagrams complement the mathematical approach to CA modeling, whose details are also presented here, and allow CAs…

Cellular Automata and Lattice Gases · Physics 2018-04-03 Vladimir García-Morales

Computer simulations have become a very powerful tool for scientific research. In order to facilitate research in computational biology, the BioDynaMo project aims at a general platform for biological computer simulations, which should be…

Distributed, Parallel, and Cluster Computing · Computer Science 2016-08-18 Lukas Breitwieser , Roman Bauer , Alberto Di Meglio , Leonard Johard , Marcus Kaiser , Marco Manca , Manuel Mazzara , Fons Rademakers , Max Talanov

This project explores speculative evolution through a 3D implementation of Conway's Game of Life, using procedural simulation to generate unfamiliar extraterrestrial organic forms. By applying a volumetric optimized workflow, the raw…

Cellular Automata and Lattice Gases · Physics 2025-05-06 Amir Hossein Khazaei

Cellular Automata (CA), as they are presented in the literature, are abstract mathematical models of computation. In this pa- per we present an alternate approach: using the CA as a model or theory of physical systems and devices. While…

Discrete Mathematics · Computer Science 2008-09-11 Donny Cheung , Carlos A. Perez-Delgado

Regulation of cell proliferation is a crucial aspect of tissue development and homeostasis and plays a major role in morphogenesis, wound healing, and tumor invasion. A phenomenon of such regulation is contact inhibition, which describes…

Cell Behavior · Quantitative Biology 2024-07-01 Steffen Lange , Jannik Schmied , Paul Willam , Anja Voss-Böhme

We present Mass-Conserving Evolution (MaCE), a general method for implementing mass conservation in Cellular Automata (CA). MaCE is a simple evolution rule that can be easily 'attached' to existing CAs to make them mass-conserving, which…

Cellular Automata and Lattice Gases · Physics 2025-07-17 Vassilis Papadopoulos , Etienne Guichard

CA has grown as potential classifier for addressing major problems in bioinformatics. Lot of bioinformatics problems like predicting the protein coding region, finding the promoter region, predicting the structure of protein and many other…

Computational Engineering, Finance, and Science · Computer Science 2014-01-13 Pokkuluri Kiran Sree , Inampudi Ramesh Babu , SSSN Usha Devi Nedunuri

To celebrate Hans Frauenfelder's achievements, we examine energy(-like) "landscapes" for complex living systems. Energy landscapes summarize all possible dynamics of some physical systems. Energy(-like) landscapes can explain some…

Quantitative Methods · Quantitative Biology 2021-10-18 Lars Koopmans , Hyun Youk

The minimal requirements for life are autopoiesis and cognition. We propose autopoietic models with cognition and perform three classes of evolutionary simulation. In our models the plasticity of the metabolic cycle and the regulation…

Cell Behavior · Quantitative Biology 2015-12-29 Hirotaka Matsufuji , Osamu Narikiyo

Conventional computers are ill suited to run CA models, and so discourage their development. By creating a hardware platform that makes a broad range of new CA algorithms practical for real applications, we hope to whet the appetite of…

comp-gas · Physics 2017-06-07 Norman Margolus

The process of morphogenesis is an evolution of the shape of an organism together with the differentiation of its parts. This process encompasses numerous biological processes ranging from embryogenesis to regeneration following crisis such…

Other Quantitative Biology · Quantitative Biology 2019-09-23 N. Bessonov , O. Butuzova , A. Minarsky , R. Penner , C. Soule , A. Tosenberger , N. Morozova

In Isliker et al. (2000b), an extended cellular automaton (X-CA) model for solar flares was introduced. In this model, the interpretation of the model's grid-variable is specified, and the magnetic field, the current, and an approximation…

Astrophysics · Physics 2009-11-07 H. Isliker , A. Anastasiadis , L. Vlahos

Motivation: Agent-based modeling is an indispensable tool for studying complex biological systems. However, existing simulators do not always take full advantage of modern hardware and often have a field-specific software design. Results:…

We show techniques of analyzing complex dynamics of cellular automata (CA) with chaotic behaviour. CA are well known computational substrates for studying emergent collective behaviour, complexity, randomness and interaction between order…

Cellular Automata and Lattice Gases · Physics 2012-03-29 Genaro J. Martinez , Andrew Adamatzky , Ramon Alonso-Sanz

Building self-adaptive and self-organizing (SASO) systems is a challenging problem, in part because SASO principles are not yet well understood and few platforms exist for exploring them. Cellular automata (CA) are a well-studied approach…

Neural and Evolutionary Computing · Computer Science 2014-05-20 David B. Knoester , Heather J. Goldsby , Christoph Adami

Understanding the rules underlying organismal development is a major unsolved problem in biology. Each cell in a developing organism responds to signals in its local environment by dividing, excreting, consuming, or reorganizing, yet how…

Cell Behavior · Quantitative Biology 2025-08-20 Ramya Deshpande , Francesco Mottes , Ariana-Dalia Vlad , Michael P. Brenner , Alma dal Co

A stochastic cellular automata (CA) model for pedestrian dynamics is presented. Our goal is to simulate different types of pedestrian movement, from regular to panic. But here we emphasize regular situations which imply that pedestrians…

Mathematical Physics · Physics 2009-09-30 Ekaterina Kirik , Tat'yana Yurgel'yan , Dmitriy Krouglov

Modeling the immune system so that its essential functionalities stand out without the need for every molecular or cellular interaction to be taken into account has been challenging for many decades. Two competing approaches have been the…

Cellular Automata and Lattice Gases · Physics 2017-11-13 Kátia K. Cassiano , Valmir C. Barbosa

We present a topology grounded, multiscale simulation platform for morphogenesis and biological active matter. Morphogenesis and biological active matter represent keystone problems in biology with additional, far-reaching implications…

Cellular automata (CA) are well-studied models of decentralized parallel computation, known for their ability to exhibit complex global behavior from simple local rules. While their dynamics have been widely explored through simulations, a…

Formal Languages and Automata Theory · Computer Science 2025-11-18 Dana Fisman , Noa Izsak