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Deep learning models often encounter challenges in making accurate inferences when there are domain shifts between the source and target data. This issue is particularly pronounced in clinical settings due to the scarcity of annotated data…

Computer Vision and Pattern Recognition · Computer Science 2026-01-06 Heng Li , Haojin Li , Jianyu Chen , Mingyang Ou , Hai Shu , Heng Miao

Deep learning-based medical image segmentation faces significant challenges arising from limited labeled data and domain shifts. While prior approaches have primarily addressed these issues independently, their simultaneous occurrence is…

Computer Vision and Pattern Recognition · Computer Science 2025-06-30 Zanting Ye , Ke Wang , Wenbing Lv , Qianjin Feng , Lijun Lu

Domain Generalization (DG) aims to reduce domain shifts between domains to achieve promising performance on the unseen target domain, which has been widely practiced in medical image segmentation. Single-source domain generalization (SDG)…

Computer Vision and Pattern Recognition · Computer Science 2024-01-05 Hanhui Wang , Huaize Ye , Yi Xia , Xueyan Zhang

Single-source domain generalization (SDG) in medical image segmentation is a challenging yet essential task as domain shifts are quite common among clinical image datasets. Previous attempts most conduct global-only/random augmentation.…

Computer Vision and Pattern Recognition · Computer Science 2022-11-29 Zixian Su , Kai Yao , Xi Yang , Qiufeng Wang , Jie Sun , Kaizhu Huang

Single-source domain generalization (SDG) aims to learn a model from a single source domain that can generalize well on unseen target domains. This is an important task in computer vision, particularly relevant to medical imaging where…

Computer Vision and Pattern Recognition · Computer Science 2024-11-11 Boqi Chen , Yuanzhi Zhu , Yunke Ao , Sebastiano Caprara , Reto Sutter , Gunnar Rätsch , Ender Konukoglu , Anna Susmelj

The field of medical image segmentation is challenged by domain generalization (DG) due to domain shifts in clinical datasets. The DG challenge is exacerbated by the scarcity of medical data and privacy concerns. Traditional single-source…

Computer Vision and Pattern Recognition · Computer Science 2024-09-10 Qiang Qiao , Wenyu Wang , Meixia Qu , Kun Su , Bin Jiang , Qiang Guo

Medical image segmentation is a critical task in computer-aided diagnosis and treatment planning. However, deep learning models often struggle to generalize across datasets due to domain shifts arising from variations in imaging protocols,…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Phuoc-Nguyen Bui , Van-Nguyen Pham , Duc-Tai Le , Junghyun Bum , Hyunseung Choo

We tackle the challenging problem of single-source domain generalization (DG) for medical image segmentation, where we train a network on one domain (e.g., CT) and directly apply it to a different domain (e.g., MR) without adapting the…

Computer Vision and Pattern Recognition · Computer Science 2026-04-29 Franz Thaler , Martin Urschler , Mateusz Kozinski , Matthias AF Gsell , Gernot Plank , Darko Stern

For medical image analysis, segmentation models trained on one or several domains lack generalization ability to unseen domains due to discrepancies between different data acquisition policies. We argue that the degeneration in segmentation…

Computer Vision and Pattern Recognition · Computer Science 2022-08-09 Ziqi Zhou , Lei Qi , Yinghuan Shi

Domain generalization (DG), aiming at models able to work on multiple unseen domains, is a must-have characteristic of general artificial intelligence. DG based on single source domain training data is more challenging due to the lack of…

Computer Vision and Pattern Recognition · Computer Science 2023-04-17 Qingyue Yang , Hongjing Niu , Pengfei Xia , Wei Zhang , Bin Li

Domain generalization (DG) aims to generalize a model trained on multiple source (i.e., training) domains to a distributionally different target (i.e., test) domain. In contrast to the conventional DG that strictly requires the availability…

Computer Vision and Pattern Recognition · Computer Science 2023-03-23 Zijian Wang , Yadan Luo , Ruihong Qiu , Zi Huang , Mahsa Baktashmotlagh

Federated Learning (FL) offers a powerful strategy for training machine learning models across decentralized datasets while maintaining data privacy, yet domain shifts among clients can degrade performance, particularly in medical imaging…

Image and Video Processing · Electrical Eng. & Systems 2024-12-31 Hongyi Pan , Debesh Jha , Koushik Biswas , Ulas Bagci

The task of single-source domain generalization (SDG) in medical image segmentation is crucial due to frequent domain shifts in clinical image datasets. To address the challenge of poor generalization across different domains, we introduce…

Image and Video Processing · Electrical Eng. & Systems 2024-07-02 Haoyu Zhao , Wenhui Dong , Rui Yu , Zhou Zhao , Du Bo , Yongchao Xu

Medical images are usually collected from multiple domains, leading to domain shifts that impair the performance of medical image segmentation models. Domain Generalization (DG) aims to address this issue by training a robust model with…

Image and Video Processing · Electrical Eng. & Systems 2025-06-13 Xi Chen , Zhiqiang Shen , Peng Cao , Jinzhu Yang , Osmar R. Zaiane

Single source domain generalization (SDG) holds promise for more reliable and consistent image segmentation across real-world clinical settings particularly in the medical domain, where data privacy and acquisition cost constraints often…

Computer Vision and Pattern Recognition · Computer Science 2024-04-04 Shahina Kunhimon , Muzammal Naseer , Salman Khan , Fahad Shahbaz Khan

In medical image segmentation tasks, Domain Generalization (DG) under the Federated Learning (FL) framework is crucial for addressing challenges related to privacy protection and data heterogeneity. However, traditional federated learning…

Computer Vision and Pattern Recognition · Computer Science 2025-10-22 Yucheng Song , Chenxi Li , Haokang Ding , Zhining Liao , Zhifang Liao

Deep learning models often struggle to maintain performance when deployed on data distributions different from their training data, particularly in real-world applications where environmental conditions frequently change. While Multi-source…

Machine Learning · Computer Science 2025-05-30 Shohei Enomoto

Single Domain Generalization (SDG) aims to train models that maintain consistent performance across diverse scenarios using data from a single source. While latent diffusion models (LDMs) show promise for augmenting limited source data, our…

Computer Vision and Pattern Recognition · Computer Science 2026-03-24 Hao Li , Yubin Xiao , Ke Liang , Mengzhu Wang , Long Lan , Kenli Li , Xinwang Liu

Recent advances in deep learning for medical image segmentation demonstrate expert-level accuracy. However, in clinically realistic environments, such methods have marginal performance due to differences in image domains, including…

Computer Vision and Pattern Recognition · Computer Science 2019-06-13 Ling Zhang , Xiaosong Wang , Dong Yang , Thomas Sanford , Stephanie Harmon , Baris Turkbey , Holger Roth , Andriy Myronenko , Daguang Xu , Ziyue Xu

Modern deep neural networks struggle to transfer knowledge and generalize across diverse domains when deployed to real-world applications. Currently, domain generalization (DG) is introduced to learn a universal representation from multiple…

Computer Vision and Pattern Recognition · Computer Science 2023-08-25 Yijun Yang , Shujun Wang , Lei Zhu , Lequan Yu
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