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Medical image segmentation plays a crucial role in clinical workflows, but domain shift often leads to performance degradation when models are applied to unseen clinical domains. This challenge arises due to variations in imaging…

Computer Vision and Pattern Recognition · Computer Science 2025-08-01 Yingkai Wang , Yaoyao Zhu , Xiuding Cai , Yuhao Xiao , Haotian Wu , Yu Yao

Deep learning models usually suffer from domain shift issues, where models trained on one source domain do not generalize well to other unseen domains. In this work, we investigate the single-source domain generalization problem: training a…

Computer Vision and Pattern Recognition · Computer Science 2023-04-24 Cheng Ouyang , Chen Chen , Surui Li , Zeju Li , Chen Qin , Wenjia Bai , Daniel Rueckert

Medical data often exhibits distribution shifts, which cause test-time performance degradation for deep learning models trained using standard supervised learning pipelines. This challenge is addressed in the field of Domain Generalization…

Computer Vision and Pattern Recognition · Computer Science 2024-11-01 Aleksandr Matsun , Numan Saeed , Fadillah Adamsyah Maani , Mohammad Yaqub

Domain generalization aims to learn a generalizable model from a known source domain for various unknown target domains. It has been studied widely by domain randomization that transfers source images to different styles in spatial space…

Computer Vision and Pattern Recognition · Computer Science 2021-03-04 Jiaxing Huang , Dayan Guan , Aoran Xiao , Shijian Lu

Medical image segmentation is challenging due to the diversity of medical images and the lack of labeled data, which motivates recent developments in federated semi-supervised learning (FSSL) to leverage a large amount of unlabeled data…

Computer Vision and Pattern Recognition · Computer Science 2025-08-06 Zhipeng Deng , Zhe Xu , Tsuyoshi Isshiki , Yefeng Zheng

Deep learning models for medical image analysis easily suffer from distribution shifts caused by dataset artifacts bias, camera variations, differences in the imaging station, etc., leading to unreliable diagnoses in real-world clinical…

Image and Video Processing · Electrical Eng. & Systems 2024-01-09 Siyuan Yan , Chi Liu , Zhen Yu , Lie Ju , Dwarikanath Mahapatra , Brigid Betz-Stablein , Victoria Mar , Monika Janda , Peter Soyer , Zongyuan Ge

Domain generalization typically requires data from multiple source domains for model learning. However, such strong assumption may not always hold in practice, especially in medical field where the data sharing is highly concerned and…

Computer Vision and Pattern Recognition · Computer Science 2022-06-30 Quande Liu , Cheng Chen , Qi Dou , Pheng-Ann Heng

Source-free test-time adaptation for medical image segmentation aims to enhance the adaptability of segmentation models to diverse and previously unseen test sets of the target domain, which contributes to the generalizability and…

Computer Vision and Pattern Recognition · Computer Science 2023-10-19 Yanyu Ye , Zhenxi Zhang , Wei Wei , Chunna Tian

Domain generalization (DG), aiming to make models work on unseen domains, is a surefire way toward general artificial intelligence. Limited by the scale and diversity of current DG datasets, it is difficult for existing methods to scale to…

Computer Vision and Pattern Recognition · Computer Science 2022-09-30 Hongjing Niu , Hanting Li , Feng Zhao , Bin Li

Domain Generalization techniques aim to enhance model robustness by simulating novel data distributions during training, typically through various augmentation or stylization strategies. However, these methods frequently suffer from limited…

Computer Vision and Pattern Recognition · Computer Science 2024-12-20 Mehrdad Noori , Milad Cheraghalikhani , Ali Bahri , Gustavo Adolfo Vargas Hakim , David Osowiechi , Moslem Yazdanpanah , Ismail Ben Ayed , Christian Desrosiers

As a recent noticeable topic, domain generalization (DG) aims to first learn a generic model on multiple source domains and then directly generalize to an arbitrary unseen target domain without any additional adaption. In previous DG…

Computer Vision and Pattern Recognition · Computer Science 2022-02-17 Yue Wang , Lei Qi , Yinghuan Shi , Yang Gao

For medical image segmentation, imagine if a model was only trained using MR images in source domain, how about its performance to directly segment CT images in target domain? This setting, namely generalizable cross-modality segmentation,…

Computer Vision and Pattern Recognition · Computer Science 2022-03-29 Ziqi Zhou , Lei Qi , Xin Yang , Dong Ni , Yinghuan Shi

Federated learning allows distributed medical institutions to collaboratively learn a shared prediction model with privacy protection. While at clinical deployment, the models trained in federated learning can still suffer from performance…

Computer Vision and Pattern Recognition · Computer Science 2021-03-11 Quande Liu , Cheng Chen , Jing Qin , Qi Dou , Pheng-Ann Heng

Domain generalization (DG) is an important problem that learns a model which generalizes to unseen test domains leveraging one or more source domains, under the assumption of shared label spaces. However, most DG methods assume access to…

Computer Vision and Pattern Recognition · Computer Science 2025-06-11 Christopher Liao , Christian So , Theodoros Tsiligkaridis , Brian Kulis

The absence of well-structured large datasets in medical computer vision results in decreased performance of automated systems and, especially, of deep learning models. Domain generalization techniques aim to approach unknown domains from a…

Image and Video Processing · Electrical Eng. & Systems 2024-06-04 Nikolaos Spanos , Anastasios Arsenos , Paraskevi-Antonia Theofilou , Paraskevi Tzouveli , Athanasios Voulodimos , Stefanos Kollias

Medical image segmentation models often struggle to generalize across different domains due to various reasons. Domain Generalization (DG) methods overcome this either through representation learning or data augmentation (DAug). While…

Computer Vision and Pattern Recognition · Computer Science 2025-05-27 Piyush Tiwary , Kinjawl Bhattacharyya , Prathosh A. P

While deep neural networks demonstrate state-of-the-art performance on a variety of learning tasks, their performance relies on the assumption that train and test distributions are the same, which may not hold in real-world applications.…

Machine Learning · Computer Science 2021-02-18 Wenyu Zhang , Mohamed Ragab , Ramon Sagarna

Accurate medical image segmentation is essential for effective diagnosis and treatment planning but is often challenged by domain shifts caused by variations in imaging devices, acquisition conditions, and patient-specific attributes.…

Image and Video Processing · Electrical Eng. & Systems 2024-12-06 Jie Bao , Zhixin Zhou , Wen Jung Li , Rui Luo

Domain Generalization (DG) aims to train models that can generalize to unseen testing domains by leveraging data from multiple training domains. However, traditional DG methods rely on the availability of multiple diverse training domains,…

Machine Learning · Computer Science 2025-03-11 Hao Yan , Marzi Heidari , Yuhong Guo

Fine-grained domain generalization (FGDG) is a more challenging task than traditional DG tasks due to its small inter-class variations and relatively large intra-class disparities. When domain distribution changes, the vulnerability of…

Computer Vision and Pattern Recognition · Computer Science 2025-03-27 Wenlong Yu , Dongyue Chen , Qilong Wang , Qinghua Hu