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Many countries have experienced at least two waves of the COVID-19 pandemic. The second wave is far more dangerous as distinct strains appear more harmful to human health, but it stems from the complacency about the first wave. This paper…

Populations and Evolution · Quantitative Biology 2022-06-29 Edilson F. Arruda , Tarun Sharma , Rodrigo e A. Alexandre , Sinnu Susan Thomas

Background: Early detection and isolation of COVID-19 patients are essential for successful implementation of mitigation strategies and eventually curbing the disease spread. With a limited number of daily COVID-19 tests performed in every…

Populations and Evolution · Quantitative Biology 2022-06-09 Mohammed Alser , Jeremie S. Kim , Nour Almadhoun Alserr , Stefan W. Tell , Onur Mutlu

Pooled testing offers an efficient solution to the unprecedented testing demands of the COVID-19 pandemic, although with potentially lower sensitivity and increased costs to implementation in some settings. Assessments of this trade-off…

Applications · Statistics 2021-07-13 Saskia Comess , Hannah Wang , Susan Holmes , Claire Donnat

The COVID-19 crisis has shown that we can only prevent the risk of mass contagion through timely, large-scale, coordinated, and decisive actions. However, frequently the models used by experts [from whom decision-makers get their main…

Applications · Statistics 2021-03-08 Mauricio Herrera

More than ever COVID-19 is putting pressure on health systems all around the world, especially in Brazil. In this study we propose an analytical approach based on statistics and machine learning that uses lab exam data coming from patients…

Machine Learning · Computer Science 2020-11-09 Vitor Bezzan , Cleber D. Rocco

The COVID-19 pandemic highlighted significant challenges in the allocation of vital healthcare resources. Existing epidemiological models, specifically compartmental models, aimed to predict the spread of the COVID-19 virus and its impact…

Physics and Society · Physics 2024-03-14 Hieu Bui , Sandra Eksioglu , Ruben Proano

The COVID-19 vaccine reduces infection risk: even if one contracts COVID-19, the probability of complications like death or hospitalization is lower. However, vaccination may prompt people to decrease preventive behaviors, such as staying…

General Economics · Economics 2023-01-10 Eiji Yamamura , Yoshiro Tsutsui , Fumio Ohtake

Efficient testing and vaccination protocols are critical aspects of epidemic management. To study the optimal allocation of limited testing and vaccination resources in a heterogeneous contact network of interacting susceptible, recovered,…

Populations and Evolution · Quantitative Biology 2026-05-12 Mingtao Xia , Lucas Böttcher , Tom Chou

Epidemic risk assessment poses inherent challenges, with traditional approaches often failing to balance health outcomes and economic constraints. This paper presents a data-driven decision support tool that models epidemiological dynamics…

Applications · Statistics 2025-11-24 Chang Zhai , Ping Chen , Zhuo Jin , David Pitt

In this study, we explore the dynamic interplay between the timing of vaccination campaigns and the trajectory of disease spread in a population. Through comprehensive data analysis and modeling, we have uncovered a counter-intuitive…

Physics and Society · Physics 2024-12-06 Piergiorgio Castioni , Sergio Gòmez , Clara Granell , Alex Arenas

The COVID-19 pandemic has placed immense strain on hospital systems worldwide, leading to critical capacity challenges. This research proposes a two-part framework to optimize hospital capacity through patient relocation strategies. The…

Artificial Intelligence · Computer Science 2026-03-18 Sadaf Tabatabaee , Hicham El Baz , Mohammed Khalil Ghali , Nagendra N. Nagarur

Effective and efficient scheduling of vaccine distribution can significantly impact vaccine uptake, which is critical to controlling the spread of infectious diseases. Ineffective scheduling can lead to waste, delays, and low vaccine…

Optimization and Control · Mathematics 2024-03-13 Nicholas Uhorchak , Ruben A. Proano , Sandra Eksioglu , Fatih Cengil , Burak Eksioglu

Vaccination campaigns have both direct and indirect effects that act to control an infectious disease as it spreads through a population. Indirect effects arise when vaccinated individuals block disease transmission in any infection chains…

Populations and Evolution · Quantitative Biology 2024-05-08 Lixin Lin , Homayoun Hamedmoghadam , Robert Shorten , Lewi Stone

Millions of young people are not immunized in low- and middle-income (LMI) countries because of low vaccine availability resulting from inefficiencies in cold supply chains. We create supply chain network design and distribution models to…

Applications · Statistics 2020-06-11 Zahra Azadi , Sandra D. Eksioglu , H. Neil Geismar

Testing is an important part of tackling the COVID-19 pandemic. Availability of testing is a bottleneck due to constrained resources and effective prioritization of individuals is necessary. Here, we discuss the impact of different…

Machine Learning · Computer Science 2020-07-30 Hagit Grushka-Cohen , Raphael Cohen , Bracha Shapira , Jacob Moran-Gilad , Lior Rokach

Over a year after the start of the COVID-19 epidemics, we are still facing the virus and it is hard to correctly predict its future spread over weeks to come, as well as the impacts of potential political interventions. Current epidemic…

Multiagent Systems · Computer Science 2021-12-03 Benoit Doussin , Carole Adam , Didier Georges

Containing an epidemic at its origin is the most desirable mitigation. Epidemics have often originated in rural areas, with rural communities among the first affected. Disease dynamics in rural regions have received limited attention, and…

In the context of SARS-CoV-2 pandemic, mathematical modelling has played a fundamental role for making forecasts, simulating scenarios and evaluating the impact of preventive political, social and pharmaceutical measures. Optimal control…

Optimization and Control · Mathematics 2022-11-01 Giovanni Ziarelli , Luca Dede' , Nicola Parolini , Marco Verani , Alfio Quarteroni

The COVID-19 pandemic has presented unprecedented challenges worldwide, with its impact varying significantly across different geographic and socioeconomic contexts. This study employs a clustering analysis to examine the diversity of…

Computational Engineering, Finance, and Science · Computer Science 2024-08-06 Morteza Maleki

Infectious disease outbreaks can have a disruptive impact on public health and societal processes. As decision making in the context of epidemic mitigation is hard, reinforcement learning provides a methodology to automatically learn…

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