English
Related papers

Related papers: A bi-objective optimization model to plan vaccinat…

200 papers

The outbreak of a novel coronavirus causing severe acute respiratory syndrome in December 2019 has escalated into a worldwide pandemic. In this work, we propose a compartmental model to describe the dynamics of transmission of infection and…

Optimization and Control · Mathematics 2022-10-25 Eleni Zavrakli , Andrew Parnell , David Malone , Ken Duffy , Subhrakanti Dey

In this paper, we introduce an algorithm designed to solve a Multilevel MOnoObjective Linear Programming Problem (ML(MO)OLPP). Our approach is a refined adaptation of Sinha and Sinha's linear programming method, incorporating the…

Optimization and Control · Mathematics 2025-03-17 Mustapha Kaci

This work introduces a novel epidemiological model that simultaneously considers multiple viral strains, reinfections due to waning immunity response over time and an optimal control formulation. This enables us to derive optimal mitigation…

Systems and Control · Electrical Eng. & Systems 2021-09-10 Edilson F. Arruda , Dayse H. Pastore , Clauda M. Dias , Shyam S. Das

Because of the rapid spread of COVID-19 to almost every part of the globe, huge volumes of data and case studies have been made available, providing researchers with a unique opportunity to find trends and make discoveries like never…

Machine Learning · Computer Science 2021-10-20 Sarwan Ali , Yijing Zhou , Murray Patterson

In this paper, we present a decision support framework for optimizing multiple aspects of vaccine distribution across a multitier cold chain network. We propose two multi-period optimization formulations within this framework: first to…

Physics and Society · Physics 2022-01-12 Shanmukhi Sripada , Ayush Jain , Prasanna Ramamoorthy , Varun Ramamohan

A mathematical model of COVID-19 with minimal compartments is developed. The model is simple enough to fit data on confirmed cases, estimate the hidden infection figure and incorporate the effect of vaccination. With the effect of the new…

Populations and Evolution · Quantitative Biology 2021-03-05 Randy L. Caga-anan , Michelle N. Raza , Grace Shelda G. Labrador , Ephrime B. Metillo

As observed during the COVID-19 pandemic, high-income countries, such as the U.S., may exhibit vaccine nationalism during a pandemic: stockpiling doses of vaccine for their own citizens and being reluctant to distribute doses of the vaccine…

Populations and Evolution · Quantitative Biology 2024-08-21 Abraham Holleran , Susan E. Martonosi , Michael Veatch

In previous articles, we formalized the problem of optimal allocation strategies for a (perfect) vaccine in an infinite-dimensional metapopulation model. The aim of the current paper is to illustrate this theoretical framework with multiple…

Optimization and Control · Mathematics 2021-12-17 Jean-François Delmas , Dylan Dronnier , Pierre-André Zitt

Infectious diseases are still a major global burden for modern society causing 13 million deaths annually. One way to reduce the morbidity and mortality rates from infectious diseases is through preventative or targeted vaccinations.…

Social and Information Networks · Computer Science 2021-01-27 Md Shahzamal , Raja Jurdak , Bernard Mans , Frank de Hoog , Dean Paini

With the increasing spread of COVID-19, it is important to systematically test more and more people. The current strategy for test-kit allocation is mostly rule-based, focusing on individuals having (a) symptoms for COVID-19, (b) travel…

Artificial Intelligence · Computer Science 2020-04-07 Arpita Biswas , Shruthi Bannur , Prateek Jain , Srujana Merugu

The pursuit of strategies that minimize the number of individuals needing vaccination to control an outbreak is a well-established area of study in mathematical epidemiology. However, for certain diseases, public policy tends to prioritize…

Populations and Evolution · Quantitative Biology 2026-01-30 J. Orestes Cerdeira , Fabio A. C. C. Chalub , Matheus Hansen

The COVID-19 disease has forced countries to make a considerable collaborative effort between scientists and governments to provide indicators to suitable follow-up the pandemic's consequences. Mathematical modeling plays a crucial role in…

Populations and Evolution · Quantitative Biology 2020-12-29 Patricio Cumsille , Oscar Rojas-Díaz , Pablo Moisset de Espanés

With the continuous rise of the COVID-19 cases worldwide, it is imperative to ensure that all those vulnerable countries lacking vaccine resources can receive sufficient support to contain the risks. COVAX is such an initiative operated by…

Computational Engineering, Finance, and Science · Computer Science 2022-01-20 Navpreet Kaur , Jason Hughes , Juntao Chen

The impact of the ongoing COVID-19 pandemic is being felt in all spheres of our lives -- cutting across the boundaries of nation, wealth, religions or race. From the time of the first detection of infection among the public, the virus…

Physics and Society · Physics 2021-10-12 Soumyajyoti Biswas , Amit Kr Mandal

The emergence of coronavirus disease 2019 (COVID-19) in the United States has forced federal and local governments to implement containment measures. Moreover, the severity of the situation has sparked engagement by both the research and…

Populations and Evolution · Quantitative Biology 2020-07-03 Min Lu , Hemant Ishwaran

Emerging in December 2019, the COVID-19 pandemic caused widespread health, economic, and social disruptions. Rapid global transmission overwhelmed healthcare systems, resulting in high infection rates, hospitalisations, and fatalities. To…

Populations and Evolution · Quantitative Biology 2025-10-08 Zacharias Komodromos , Kleanthis Malialis , Panayiotis Kolios

The spread of COVID-19 makes it essential to investigate its prevalence. In such investigation research, as far as we know, the widely-used sampling methods didn't use the information sufficiently about the numbers of the previously…

Applications · Statistics 2022-01-04 Ze Liu , Siyu Yi , Jianghu , Dong , Min-Qian Liu , Yongdao Zhou

Timely and effective decision-making is critical during epidemics to reduce preventable infections and deaths. This demands integrated models that jointly capture disease dynamics, vaccine distribution, regional disparities, and behavioral…

Social and Information Networks · Computer Science 2025-11-26 Kimiya Jozani , Nihal A. Sageer , Hode Eldardiry , Sait Tunc , Esra Buyuktahtakin Toy

The challenges posed by epidemics and pandemics are immense, especially if the causes are novel. This article introduces a versatile open-source simulation framework designed to model intricate dynamics of infectious diseases across diverse…

Multiagent Systems · Computer Science 2023-11-17 Zenin Easa Panthakkalakath , Neeraj , Jimson Mathew

A major strategy to prevent the spread of COVID-19 is the limiting of in-person contacts. However, this is impractical or impossible for the many disabled people who do not live in care facilities, but still require caregivers. We seek to…

Social and Information Networks · Computer Science 2021-09-28 Thomas E. Valles , Hannah Shoenhard , Joseph Zinski , Sarah Trick , Mason A. Porter , Michael R. Lindstrom