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Confocal laser-scanning microscopy (CLSM) is one of the most popular optical architectures for fluorescence imaging. In CLSM, a focused laser beam excites the fluorescence emission from a specific specimen position. Some actuators scan the…

Image and Video Processing · Electrical Eng. & Systems 2023-05-10 Alessandro Zunino , Marco Castello , Giuseppe Vicidomini

Interferometry provides highly sensitive access to optical phase and is central to much of modern metrology and phase imaging methods. Conventional implementations, however, often face trade-offs between mechanical stability and…

Single-pixel imaging has emerged as a key technique in fluorescence microscopy, where fast acquisition and reconstruction are crucial. In this context, images are reconstructed from linearly compressed measurements. In practice, total…

Image and Video Processing · Electrical Eng. & Systems 2025-07-28 Serban C. Tudosie , Valerio Gandolfi , Shivaprasad Varakkoth , Andrea Farina , Cosimo D'Andrea , Simon Arridge

Multi-modal sensor data fusion takes advantage of complementary or reinforcing information from each sensor and can boost overall performance in applications such as scene classification and target detection. This paper presents a new…

Computer Vision and Pattern Recognition · Computer Science 2024-02-08 Hersh Vakharia , Xiaoxiao Du

Stimulated Raman scattering (SRS) microscopy offers great potential to surpass fluorescent-based approaches, owing to the sharp linewidth of Raman vibrations amenable to super-multiplex cell imaging, but currently lacks one crucial…

Real time, singleshot multispectral imaging systems are crucial for environment monitoring and biomedical imaging. Most singleshot multispectral imagers rely on complex computational backends, which precludes real time operations. In this…

Optics · Physics 2025-02-27 Romil Audhkhasi , Ningzhi Xie , Johannes E. Fröch , Arka Majumdar

This paper presents how photonics associated with new arising detection technologies is able to provide fully integrated instrument for coherent beam combination applied to astrophysical interferometry. The feasibility and operation of…

Instrumentation and Methods for Astrophysics · Physics 2010-11-02 Pierre Kern , Etienne Le Coärer , Pierre Benech

Multimode fibers recently emerged as compact minimally-invasive probes for high-resolution deep-tissue imaging. However, the commonly used silica fibers have a relatively low numerical aperture (NA) limiting the spatial resolution of a…

Optics · Physics 2024-07-09 Zhouping Lyu , Lyubov Amitonova

We propose an interferometric scheme for the estimation of a linear combination with non-negative weights of an arbitrary number $M>1$ of unknown phase delays, distributed across an $M$-channel linear optical network, with…

Quantum Physics · Physics 2019-12-04 Dario Gatto , Paolo Facchi , Frank Narducci , Vincenzo Tamma

Optical methods based on thin multimode fibers (MMFs) are promising tools for measuring neuronal activity in deep brain regions of freely moving mice thanks to their small diameter. However, current methods are limited: while fiber…

Structured illumination microscopy (SIM) enables live cell, super-resolution imaging at high speeds. SIM uses sophisticated optical systems to generate pre-determined excitation light patterns, and reconstruction algorithms to enhance the…

We demonstrate single-pixel imaging in the spectral domain by encoding Fourier probe patterns onto the spectrum of a superluminescent laser diode using a programmable optical filter. As a proof-of-concept, we measure the…

Optics · Physics 2020-02-26 Piotr Ryczkowski , Caroline Amiot , John M. Dudley , Goery Genty

Infrared and Visible Image Fusion (IVIF) has shown promise in visual tasks under challenging environments, but fusion under unregistered conditions faces inherent misalignments. Current studies to solve them either predict the deformation…

Computer Vision and Pattern Recognition · Computer Science 2026-05-14 Xingyuan Li , Haoyuan Xu , Xingyue Zhu , Jun Ma , Yang Zou , Zhiying Jiang , Jinyuan Liu

The present work deals with a curvature sensor that consists of two segments of asymmetric multicore fiber (MCF) fusion spliced with standard single mode fiber (SMF). The MCF comprises three strongly coupled cores; one of such cores is at…

Tapered optical fibers (TFs), with diameters gradually reduced from hundreds of microns to the micron scale, offer key advantages over conventional flat optical fibers (FFs), including uniform illumination, efficient long-range signal…

Optics · Physics 2026-02-03 Mingliang Xu , Fangyuan Li , Yuxin Leng , Ruxin Li , Fei He

Light-sheet fluorescence microscopy (LSFM) enables real-time whole-brain functional imaging in zebrafish larvae. Conventional one photon LSFM can however induce undesirable visual stimulation due to the use of visible excitation light. The…

Multimodal image fusion (MMIF) integrates information from different modalities to obtain a comprehensive image, aiding downstream tasks. However, existing research focuses on complementary information fusion and training strategies,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-12 Dan He , Guofen Wang , Weisheng Li , Yucheng Shu , Wenbo Li , Lijian Yang , Yuping Huang , Feiyan Li

High-content biological microscopy targets high-resolution imaging across large fields-of-view (FOVs). Recent works have demonstrated that computational imaging can provide efficient solutions for high-content microscopy. Here, we use…

Image and Video Processing · Electrical Eng. & Systems 2019-03-28 Li-Hao Yeh , Shwetadwip Chowdhury , Laura Waller

A major open challenge in neuroscience is the ability to measure and perturb neural activity in vivo from well-defined neural sub-populations at cellular resolution anywhere in the brain. However, limitations posed by scattering and…

Biological Physics · Physics 2017-11-10 Shay Ohayon , Antonio Miguel Caravaca-Aguirre , Rafael Piestun , James J. DiCarlo

Blind source separation is a common processing tool to analyse the constitution of pixels of hyperspectral images. Such methods usually suppose that pure pixel spectra (endmembers) are the same in all the image for each class of materials.…

Methodology · Statistics 2022-10-03 Charlotte Revel , Yannick Deville , Véronique Achard , Xavier Briottet
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