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Computational methods are the most effective tools we have besides scientific experiments to explore the properties of complex biological systems. Progress is slowing because digital silicon computers have reached their limits in terms of…

Quantum Physics · Physics 2020-04-03 Viv Kendon

A hypercomplex representation of DNA is proposed to facilitate comparison of DNA sequences with fuzzy composition. Using hypercomplex number representation, conventional sequence analysis method, such as, dot matrix analysis, dynamic…

Quantitative Methods · Quantitative Biology 2023-08-03 Jian-Jun Shu , Yajing Li

Technology progress in DNA sequencing boosts the genomic database growth at faster and faster rate. Compression, accompanied with random access capabilities, is the key to maintain those huge amounts of data. In this paper we present an…

Computational Engineering, Finance, and Science · Computer Science 2011-03-14 Szymon Grabowski , Sebastian Deorowicz

We introduce a model for simulating mutation of prokaryote DNA sequences. Using that model we can then evaluated traditional techniques like parsimony and maximum likelihood methods for computing phylogenetic relationships. We also use the…

Populations and Evolution · Quantitative Biology 2007-05-23 Matthew J. Berryman , Andrew Allison , Derek Abbott

The past few years have seen a surge of interest in the field of probabilistic logic learning and statistical relational learning. In this endeavor, many probabilistic logics have been developed. ProbLog is a recent probabilistic extension…

Programming Languages · Computer Science 2011-03-04 Angelika Kimmig , Bart Demoen , Luc De Raedt , Vítor Santos Costa , Ricardo Rocha

The burst approximation is a widely used technique to simplify stochastic gene expression models. However, the dynamics and analytical properties of the protein number distribution in gene expression models under the burst approximation are…

Biological Physics · Physics 2026-05-06 Yuntao Lu , Yunxin Zhang

Ongoing progress in computational intelligence (CI) has led to an increased desire to apply CI techniques for the purpose of improving software engineering processes, particularly software testing. Existing state-of-the-art automated…

Neural and Evolutionary Computing · Computer Science 2023-02-16 Jarrod Goschen , Anna Sergeevna Bosman , Stefan Gruner

Contraction Clustering (RASTER) is a single-pass algorithm for density-based clustering of 2D data. It can process arbitrary amounts of data in linear time and in constant memory, quickly identifying approximate clusters. It also exhibits…

Data Structures and Algorithms · Computer Science 2020-09-17 Gregor Ulm , Simon Smith , Adrian Nilsson , Emil Gustavsson , Mats Jirstrand

To model combinatorial decision problems involving uncertainty and probability, we introduce stochastic constraint programming. Stochastic constraint programs contain both decision variables (which we can set) and stochastic variables…

Artificial Intelligence · Computer Science 2009-03-09 Toby Walsh

With ever-increasing dataset sizes, subset selection techniques are becoming increasingly important for a plethora of tasks. It is often necessary to guide the subset selection to achieve certain desiderata, which includes focusing or…

Computer Vision and Pattern Recognition · Computer Science 2022-03-10 Suraj Kothawade , Vishal Kaushal , Ganesh Ramakrishnan , Jeff Bilmes , Rishabh Iyer

Inspired by the use of random projections in biological sensing systems, we present a new algorithm for processing data in classification problems. This is based on observations of the human brain and the fruit fly's olfactory system and…

Machine Learning · Statistics 2022-07-28 Nina Dekoninck Bruhin , Bryn Davies

In this paper, we propose Proq, a runtime assertion scheme for testing and debugging quantum programs on a quantum computer. The predicates in Proq are represented by projections (or equivalently, closed subspaces of the state space),…

Programming Languages · Computer Science 2020-06-02 Gushu Li , Li Zhou , Nengkun Yu , Yufei Ding , Mingsheng Ying , Yuan Xie

We present EvoSort, a general-purpose adaptive parallel parallel sorting framework accessible at the Python level. EvoSort employs a Genetic Algorithm (GA) to automatically discover and refine critical parameters, including insertion sort…

Distributed, Parallel, and Cluster Computing · Computer Science 2026-01-05 Shashank Raj , Kalyanmoy Deb

In order to associate complex traits with genetic polymorphisms, genome-wide association studies process huge datasets involving tens of thousands of individuals genotyped for millions of polymorphisms. When handling these datasets, which…

Computational Engineering, Finance, and Science · Computer Science 2013-05-02 Elmar Peise , Diego Fabregat , Yurii Aulchenko , Paolo Bientinesi

This paper reviews strategies for solving problems encountered when analyzing large genomic data sets and describes the implementation of those strategies in R by packages from the Bioconductor project. We treat the scalable processing,…

Genomics · Quantitative Biology 2014-09-11 Michael Lawrence , Martin Morgan

The application of deep learning techniques in software engineering becomes increasingly popular. One key problem is developing high-quality and easy-to-use source code representations for code-related tasks. The research community has…

Software Engineering · Computer Science 2023-11-07 Zhiwei Xu , Min Zhou , Xibin Zhao , Yang Chen , Xi Cheng , Hongyu Zhang

We present a novel clustering algorithm, visClust, that is based on lower dimensional data representations and visual interpretation. Thereto, we design a transformation that allows the data to be represented by a binary integer array…

Computer Vision and Pattern Recognition · Computer Science 2024-05-31 Anna Breger , Clemens Karner , Martin Ehler

Massive volumes of high-dimensional data that evolves over time is continuously collected by contemporary information processing systems, which brings up the problem of organizing this data into clusters, i.e. achieve the purpose of…

Machine Learning · Computer Science 2019-10-22 Di Xu , Tianhang Long , Junbin Gao

Representing real-time data as a sum of complex exponentials provides a compact form that enables both denoising and extrapolation. As a fully data-driven method, the Estimation of Signal Parameters via Rotational Invariance Techniques…

Strongly Correlated Electrons · Physics 2026-03-27 Andre Erpenbeck , Yuanran Zhu , Yang Yu , Lei Zhang , Richard Gerum , Olga Goulko , Chao Yang , Guy Cohen , Emanuel Gull

Attributed graphs model real networks by enriching their nodes with attributes accounting for properties. Several techniques have been proposed for partitioning these graphs into clusters that are homogeneous with respect to both semantic…

Social and Information Networks · Computer Science 2017-08-29 Alessandro Baroni , Alessio Conte , Maurizio Patrignani , Salvatore Ruggieri