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Many rare diseases offer limited established treatment options, leading patients to switch therapies when new medications emerge. To analyze the impact of such treatment switches within the low sample size limitations of rare disease…

Field observations form the basis of many scientific studies, especially in ecological and social sciences. Despite efforts to conduct such surveys in a standardized way, observations can be prone to systematic measurement errors. The…

Methodology · Statistics 2021-08-31 Shiv Shankar , Daniel Sheldon

We analyze the disordered Riemannian geometry resulting from random perturbations of the Euclidean metric. We focus on geodesics, the paths traced out by a particle traveling in this quenched random environment. By taking the point of the…

Probability · Mathematics 2016-06-21 Tom LaGatta , Jan Wehr

Joint modelling of longitudinal observations and event times continues to remain a topic of considerable interest in biomedical research. For example, in HIV studies, the longitudinal bio-marker such as CD4 cell count in a patient's blood…

Methodology · Statistics 2024-07-19 Srimanti Dutta , Arindom Chakraborty , Dipankar Bandyopadhyay

High-dimensional multivariate longitudinal data, which arise when many outcome variables are measured repeatedly over time, are becoming increasingly common in social, behavioral and health sciences. We propose a latent variable model for…

Methodology · Statistics 2025-12-09 Sze Ming Lee , Yunxiao Chen , Tony Sit

Joint models for longitudinal and time-to-event data have seen many developments in recent years. Though spatial joint models are still rare and the traditional proportional hazards formulation of the time-to-event part of the model is…

Methodology · Statistics 2024-06-25 Anja Rappl , Thomas Kneib , Stefan Lang , Elisabeth Bergherr

In this work, we propose to study the global geometrical properties of generative models. We introduce a new Riemannian metric to assess the similarity between any two data points. Importantly, our metric is agnostic to the parametrization…

Machine Learning · Computer Science 2024-07-17 Beomsu Kim , Michael Puthawala , Jong Chul Ye , Emanuele Sansone

We present a novel framework for variable selection in Fr\'echet regression with responses in general metric spaces, a setting increasingly relevant for analyzing non-Euclidean data such as probability distributions and covariance matrices.…

Statistics Theory · Mathematics 2025-09-18 Haoyi Yang , Satarupa Bhattacharjee , Lingzhou Xue , Bing Li

We propose a versatile and computationally efficient estimating equation method for a class of hierarchical multiplicative generalized linear mixed models with additive dispersion components, based on explicit modelling of the covariance…

Methodology · Statistics 2010-08-18 René Holst , Bent Jørgensen

This monograph resolves - in a dense class of cases - several open problems concerning geodesics in i.i.d. first-passage percolation on $\mathbb{Z}^d$. Our primary interest is in the empirical measures of edge-weights observed along…

Probability · Mathematics 2021-10-04 Erik Bates

A methodology is developed for data analysis based on empirically constructed geodesic metric spaces. For a probability distribution, the length along a path between two points can be defined as the amount of probability mass accumulated…

Statistics Theory · Mathematics 2019-03-18 Kei Kobayashi , Henry P. Wynn

We consider weighted geodesic random walks in a complete Riemannian manifold $(M,g)$. We show that for almost all sequences of weights (with respect to a suitable measure), these weighted geodesic random walks satisfy, when suitably scaled,…

Probability · Mathematics 2026-02-20 Rik Versendaal

In generalized regression models the effect of continuous covariates is commonly assumed to be linear. This assumption, however, may be too restrictive in applications and may lead to biased effect estimates and decreased predictive…

Methodology · Statistics 2023-11-01 Nikolai Spuck , Matthias Schmid , Moritz Berger

Matrix-valued covariance functions are crucial to geostatistical modeling of multivariate spatial data. The classical assumption of symmetry of a multivariate covariance function is overlay restrictive and has been considered as unrealistic…

Statistics Theory · Mathematics 2017-11-28 Alfredo Alegría , Emilio Porcu , Reinhard Furrer

We study the asymptotic properties of geodesically convex $M$-estimation on non-linear spaces. Namely, we prove that under very minimal assumptions besides geodesic convexity of the cost function, one can obtain consistency and asymptotic…

Statistics Theory · Mathematics 2023-05-08 Victor-Emmanuel Brunel

Regression is an essential and fundamental methodology in statistical analysis. The majority of the literature focuses on linear and nonlinear regression in the context of the Euclidean space. However, regression models in non-Euclidean…

Methodology · Statistics 2024-09-06 Jinzhao Liu , Chao Liu , Jian Qing Shi , Tom Nye

This paper is concerned with the problem of distributed extended object tracking, which aims to collaboratively estimate the state and extension of an object by a network of nodes. In traditional tracking applications, most approaches…

Systems and Control · Computer Science 2019-03-04 Junhao Hua , Chunguang Li

We develop a new method for visualizing and refining the invariances of learned representations. Specifically, we test for a general form of invariance, linearization, in which the action of a transformation is confined to a low-dimensional…

Computer Vision and Pattern Recognition · Computer Science 2020-07-28 Olivier J. Hénaff , Eero P. Simoncelli

We study uniform consistency in nonparametric mixture models as well as closely related mixture of regression (also known as mixed regression) models, where the regression functions are allowed to be nonparametric and the error…

Statistics Theory · Mathematics 2022-12-29 Bryon Aragam , Ruiyi Yang

Missing data and noisy observations pose significant challenges for reliably predicting events from irregularly sampled multivariate time series (longitudinal) data. Imputation methods, which are typically used for completing the data prior…

Machine Learning · Statistics 2017-08-17 Hossein Soleimani , James Hensman , Suchi Saria