English
Related papers

Related papers: DNAGPT: A Generalized Pre-trained Tool for Versati…

200 papers

Recent work on time-series models has leveraged self-supervised training to learn meaningful features and patterns in order to improve performance on downstream tasks and generalize to unseen modalities. While these pretraining methods have…

Machine Learning · Computer Science 2026-04-10 Paul Quinlan , Qingguo Li , Xiaodan Zhu

Language models, especially transformer-based ones, have achieved colossal success in NLP. To be precise, studies like BERT for NLU and works like GPT-3 for NLG are very important. If we consider DNA sequences as a text written with an…

Genomics · Quantitative Biology 2026-01-21 Musa Nuri Ihtiyar , Arzucan Ozgur

With the success of large-scale pre-training in language tasks, there is an increasing trend of applying it to the domain of life sciences. In particular, pre-training methods based on DNA sequences have received increasing attention…

Artificial Intelligence · Computer Science 2024-09-10 Chaoqi Liang , Lifeng Qiao , Peng Ye , Nanqing Dong , Jianle Sun , Weiqiang Bai , Yuchen Ren , Xinzhu Ma , Hongliang Yan , Chunfeng Song , Wanli Ouyang , Wangmeng Zuo

Distantly supervised relation extraction is widely used to extract relational facts from text, but suffers from noisy labels. Current relation extraction methods try to alleviate the noise by multi-instance learning and by providing…

Computation and Language · Computer Science 2019-06-21 Christoph Alt , Marc Hübner , Leonhard Hennig

We propose a novel domain-specific generative pre-training (DS-GPT) method for text generation and apply it to the product titleand review summarization problems on E-commerce mobile display.First, we adopt a decoder-only transformer…

Computation and Language · Computer Science 2021-12-17 Xueying Zhang , Yunjiang Jiang , Yue Shang , Zhaomeng Cheng , Chi Zhang , Xiaochuan Fan , Yun Xiao , Bo Long

Large Language Models (LLMs) demonstrate remarkable generalizability across diverse tasks, yet genomic foundation models (GFMs) still require separate finetuning for each downstream application, creating significant overhead as model sizes…

Genomics · Quantitative Biology 2025-02-07 Zehui Li , Vallijah Subasri , Yifei Shen , Dongsheng Li , Yiren Zhao , Guy-Bart Stan , Caihua Shan

For protein sequence datasets, unlabeled data has greatly outpaced labeled data due to the high cost of wet-lab characterization. Recent deep-learning approaches to protein prediction have shown that pre-training on unlabeled data can yield…

Machine Learning · Computer Science 2020-12-02 Pascal Sturmfels , Jesse Vig , Ali Madani , Nazneen Fatema Rajani

The future development of an AI scientist, a tool that is capable of integrating a variety of experimental data and generating testable hypotheses, holds immense potential. So far, bespoke machine learning models have been created to…

Quantitative Methods · Quantitative Biology 2024-03-05 Tyler D. Ross , Ashwin Gopinath

This paper presents DNAct, a language-conditioned multi-task policy framework that integrates neural rendering pre-training and diffusion training to enforce multi-modality learning in action sequence spaces. To learn a generalizable…

Robotics · Computer Science 2024-03-11 Ge Yan , Yueh-Hua Wu , Xiaolong Wang

Molecules play a crucial role in biomedical research and discovery, particularly in the field of small molecule drug development. Given the rapid advancements in large language models, especially the recent emergence of reasoning models, it…

Artificial Intelligence · Computer Science 2025-12-12 Chenyang Zuo , Siqi Fan , Zaiqing Nie

This open access book provides a comprehensive overview of the state of the art in research and applications of Foundation Models and is intended for readers familiar with basic Natural Language Processing (NLP) concepts. Over the recent…

Computation and Language · Computer Science 2023-02-20 Gerhard Paaß , Sven Giesselbach

Graph pre-training has been concentrated on graph-level tasks involving small graphs (e.g., molecular graphs) or learning node representations on a fixed graph. Extending graph pre-trained models to web-scale graphs with billions of nodes…

Machine Learning · Computer Science 2025-11-07 Yufei He , Zhenyu Hou , Yukuo Cen , Jun Hu , Feng He , Xu Cheng , Jie Tang , Bryan Hooi

The Generative Pre-trained Transformer (GPT) represents a notable breakthrough in the domain of natural language processing, which is propelling us toward the development of machines that can understand and communicate using language in a…

Currently, the construction of large language models in specific domains is done by fine-tuning on a base model. Some models also incorporate knowledge bases without the need for pre-training. This is because the base model already contains…

Computation and Language · Computer Science 2023-08-22 Zhixiao Qi , Yijiong Yu , Meiqi Tu , Junyi Tan , Yongfeng Huang

Unsupervised pre-training of large neural models has recently revolutionized Natural Language Processing. By warm-starting from the publicly released checkpoints, NLP practitioners have pushed the state-of-the-art on multiple benchmarks…

Computation and Language · Computer Science 2022-08-10 Sascha Rothe , Shashi Narayan , Aliaksei Severyn

Given the ubiquity of graph data, it is intriguing to ask: Is it possible to train a graph foundation model on a broad range of graph data across diverse domains? A major hurdle toward this goal lies in the fact that graphs from different…

Machine Learning · Computer Science 2024-09-24 Xingtong Yu , Chang Zhou , Yuan Fang , Xinming Zhang

A foundation model like GPT elicits many emergent abilities, owing to the pre-training with broad inclusion of data and the use of the powerful Transformer architecture. While foundation models in natural languages are prevalent, can we…

Machine Learning · Computer Science 2025-06-18 Ziyuan Tang , Jie Chen

Large language models (LLMs) have notably enhanced the fluency and diversity of machine-generated text. However, this progress also presents a significant challenge in detecting the origin of a given text, and current research on detection…

Computation and Language · Computer Science 2023-10-05 Xianjun Yang , Wei Cheng , Yue Wu , Linda Petzold , William Yang Wang , Haifeng Chen

The pre-training on the graph neural network model can learn the general features of large-scale networks or networks of the same type by self-supervised methods, which allows the model to work even when node labels are missing. However,…

Machine Learning · Computer Science 2022-04-19 Ke-jia Chen , Jiajun Zhang , Linpu Jiang , Yunyun Wang , Yuxuan Dai

Fine-tuning pre-trained Neural Machine Translation (NMT) models is the dominant approach for adapting to new languages and domains. However, fine-tuning requires adapting and maintaining a separate model for each target task. We propose a…

Computation and Language · Computer Science 2019-09-19 Ankur Bapna , Naveen Arivazhagan , Orhan Firat