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Variational quantum algorithms provide a direct, physics-based approach to protein structure prediction, but their accuracy is limited by the coarse resolution of the energy landscapes generated on current noisy devices. We propose a hybrid…

Emerging Technologies · Computer Science 2025-10-09 Yuqi Zhang , Yuxin Yang , Feixiong Chen , Cheng-Chang Lu , Nima Saeidi , Samuel L. Volchenboum , Junhan Zhao , Siwei Chen , Weiwen Jiang , Qiang Guan

Quantum computing has gained a lot of attention recently, and scientists have seen potential applications in this field using quantum computing for Cryptography and Communication to Machine Learning and Healthcare. Protein folding has been…

Quantum Physics · Physics 2022-11-16 Hasan Mustafa , Sai Nandan Morapakula , Prateek Jain , Srinjoy Ganguly

Quantum annealing is a heuristic optimization algorithm that exploits quantum evolution to approximately find lowest energy states. Quantum annealers have scaled up in recent years to tackle increasingly larger and more highly connected…

Quantum Physics · Physics 2025-07-04 Humberto Munoz Bauza , Daniel A. Lidar

Most non-relativistic interacting quantum many-body systems, such as atomic and molecular ensembles or materials, are naturally described in terms of continuous-space Hamiltonians. The simulation of their ground-state properties on digital…

Quantum Physics · Physics 2024-09-11 Friederike Metz , Gabriel Pescia , Giuseppe Carleo

Quantum error detection can produce unbiased expectation values that exponentially converge to noiseless results as the code distance is increased. Despite this, its performance as an error mitigation technique is relatively understudied on…

Quantum Physics · Physics 2026-05-05 Yanis Le Fur , Ethan Egger , Hong-Ye Hu , Vincent Russo , William J. Zeng , Ryan LaRose

We explore the potential application of quantum annealing to address the protein structure problem. To this end, we compare several proposed ab initio protein folding models for quantum computers and analyze their scaling and performance…

Quantum Physics · Physics 2026-04-27 Timon Scheiber , Matthias Heller , Andreas Giebel

Quantum computers promise to efficiently solve important problems that are intractable on a conventional computer. Quantum computational algorithms have the potential to be an exciting new way of studying quantum cosmology. In quantum…

Quantum Physics · Physics 2019-12-03 Anirban Ganguly , Bikash K. Behera , Prasanta K. Panigrahi

In recent years, there has been a growing interest in the development of quantum emulation. However, existing studies often struggle to achieve broad applicability, high performance, and efficient resource and memory utilization. To address…

Quantum Physics · Physics 2025-11-06 Tran Van Duy , Tuan Hai Vu , Vu Trung Duong Le , Hoai Luan Pham , Yasuhiko Nakashima

Quantum computing is an emerging field on the multidisciplinary interface between physics, engineering, and computer science with the potential to make a large impact on computational intelligence (CI). The aim of this paper is to introduce…

Quantum annealing is an emerging metaheuristic used for solving combinatorial optimisation problems. However, hardware based physical quantum annealers are primarily limited to a single vendor. As an alternative, we can discretise the…

Quantum Physics · Physics 2023-07-20 Ameya Bhave , Ajinkya Borle

Accurately describing strongly correlated systems with affordable quantum resources remains a central challenge for quantum chemistry applications on near and intermediate-term quantum computers. The localized active space self-consistent…

Stochastic Unit Commitment (SUC) has been proposed to manage the uncertainties driven by renewable integration, but it leads to significant computational complexity. When accelerated by Benders Decomposition (BD), the master problem becomes…

Quantum Physics · Physics 2026-02-25 Wei Hong , Wangkun Xu , Fei Teng

Variational quantum algorithms offer fascinating prospects for the solution of combinatorial optimization problems using digital quantum computers. However, the achievable performance in such algorithms and the role of quantum correlations…

Quantum Physics · Physics 2024-01-10 Gopal Chandra Santra , Fred Jendrzejewski , Philipp Hauke , Daniel J. Egger

Quantum annealing has shown promise for finding solutions to difficult optimization problems, including protein folding. Recently, we used the D-Wave Advantage quantum annealer to explore the folding problem in a coarse-grained lattice…

Quantum Physics · Physics 2024-02-15 Anders Irbäck , Lucas Knuthson , Sandipan Mohanty , Carsten Peterson

Symmetry is fundamental in the description and simulation of quantum systems. Leveraging symmetries in classical simulations of many-body quantum systems can results in significant overhead due to the exponentially growing size of some…

Numerous challenges persist in High Energy Physics (HEP), the addressing of which requires advancements in detection technology, computational methods, data analysis frameworks, and phenomenological designs. We provide a concise yet…

High Energy Physics - Phenomenology · Physics 2025-03-11 Yaquan Fang , Christina Gao , Ying-Ying Li , Jing Shu , Yusheng Wu , Hongxi Xing , Bin Xu , Lailin Xu , Chen Zhou

Variational algorithms have received significant attention in recent years due to their potential to solve practical problems using noisy intermediate-scale quantum (NISQ) devices. A fundamental step of these algorithms is the evaluation of…

The quantum approximate optimization algorithm (QAOA) is a hybrid variational quantum-classical algorithm that solves combinatorial optimization problems. While there is evidence suggesting that the fixed form of the standard QAOA ansatz is…

Simulating electronic structure on a quantum computer requires encoding of fermionic systems onto qubits. Common encoding methods transform a fermionic system of $N$ spin-orbitals into an $N$-qubit system, but many of the fermionic…

Quantum Physics · Physics 2022-06-07 Yu Shee , Pei-Kai Tsai , Cheng-Lin Hong , Hao-Chung Cheng , Hsi-Sheng Goan

Physical design refers to mathematical optimization of a desired objective (e.g. strong light--matter interactions, or complete quantum state transfer) subject to the governing dynamical equations, such as Maxwell's or Schrodinger's…

Optics · Physics 2023-04-03 Shai Gertler , Zeyu Kuang , Colin Christie , Owen D. Miller
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