Related papers: Bubble Cloud Characteristics and Ablation Efficien…
A variety of approaches have been used to model the dynamics of a single, isolated bubble nucleated by a microsecond length high-amplitude ultrasound pulse (e.g., a histotripsy pulse). Until recently, the lack of single--bubble experimental…
Thrombolytic occlusions in stroke, pulmonary embolism and the peripheral vasculature are increasingly treated with aspiration, a catheter-based approach that employs suction to extract clots through a hollow catheter lumen. Unfortunately,…
To address existing challenges with intravascular mechanical thrombectomy devices, a novel ultrasound-enhanced aspiration approach is being developed to mechanically degrade clots using cavitation. This method employs standing waves within…
Heat enhancement at the target in a High Intensity Focused Ultrasound (HIFU) field is investigated by considering the effects of the injection of microbubbles in the vicinity of the tumor to be ablated. The interaction between the bubble…
Femtosecond pulses hold great promise for high-precision tissue removal. However, ablation rates are severely limited by the need to keep average laser power low to avoid collateral damage due to heat accumulation. Furthermore, previously…
The dynamics of bubble clouds induced by high-intensity focused ultrasound are investigated in a regime where the cloud size is similar to the ultrasound wavelength. High-speed images show that the cloud is asymmetrical; the bubbles nearest…
This work investigates the fundamental role of cavitation bubble clouds in stone comminution by focused ultrasound. The fragmentation of stones by ultrasound has applications in medical lithotripsy for the comminution of kidney stones or…
While the ultrasound and cavitation based therapies have mushroomed over the years, there is a lack of online monitoring the cavitation bubble dynamics in biological tissue. {\color{black}Here we demonstrate that with ultrasonic plane wave…
Focused ultrasound stimulated microbubbles have been shown to be capable of inducing blood flow shutdown and necrosis in a range of tissue types in an approach termed antivascular ultrasound or mechanical ablation. In oncology, this…
We conduct experiments and numerical simulations of the dynamics of bubble clouds nucleated on the surface of an epoxy cylindrical stone model during burst wave lithotripsy (BWL). In the experiment, the bubble clouds are visualized and…
Transparent biological tissues can be precisely dissected with ultrafast lasers using optical breakdown in the tight focal zone. Typically, tissues are cut by sequential application of pulses, each of which produces a single cavitation…
We investigate the process of cloud cavitation collapse through large-scale simulation of a cloud composed of 12500 gas bubbles. A finite volume scheme is used on a structured Cartesian grid to solve the Euler equations, and the bubbles are…
A large-scale molecular dynamics (MD) simulation of acoustic cavitation in a simple liquid was performed using the supercomputer Fugaku. The system, consisting of approximately 100 billion atoms, was subjected to ultrasonic irradiation.…
Current interstitial techniques of tumor ablation face challenges that ultrasound technologies could meet. The ablation radius and directionality of the ultrasound beam could improve the efficiency and precision. Here, a 9gauge…
High Intensity Focused Ultrasound (HIFU) is a promising therapy for thermal ablation and hyperthermia, characterised by it noninvasiveness, high penetration depth. Effective HIFU thermo-therapy requires the ability to accurately predict…
Acoustic waves are dissipated when they pass through bubbly media. Dissipation by bubbles takes place through thermal damping (Td), radiation damping (Rd) and damping due to the friction of the liquid (Ld) and friction of the coating (Cd).…
Ultrasonic irradiation of liquids, such as water-alcohol solutions, results in cavitation or the formation of small bubbles. Cavitation bubbles are generated in real solutions without the use of optical traps making our system as close to…
Mechanisms for non-invasive target drug delivery using microbubbles and ultrasound have attracted growing interest. Microbubbles can be loaded with a therapeutic payload and tracked via ultrasound imaging to selectively release their…
The influence of initial shape imperfections on the post-buckling and translational behavior of encapsulated microbubbles is investigated subject to acoustic excitation in an unbounded flow. Bifurcation analysis reveals that imperfections…
The acoustic bubble is an example of a highly nonlinear system which is the building block of several applications and phenomena ranging from underwater acoustics to sonochemistry and medicine. Nonlinear behavior of bubbles, and most…