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Multilayer networks preserve full information about the different interactions among the constituents of a complex system, and have recently proven quite useful in modelling transportation networks, social circles, and the human brain. A…

Physics and Society · Physics 2020-06-29 Andrea Santoro , Vincenzo Nicosia

Chemical reaction network theory is a field of applied mathematics concerned with modeling chemical systems, and can be used in other contexts such as in systems biology to study cellular signaling pathways or epidemiology to study the…

Algebraic Geometry · Mathematics 2024-06-17 Maize Curiel , Elise Farr , Galileo Fries , Luis David García Puente , Julian Hutchins , Vuong Nguyen Hoang

In analogy of classical Kolmogorov complexity we develop a theory of the algorithmic information in bits contained in any one of continuously many pure quantum states: quantum Kolmogorov complexity. Classical Kolmogorov complexity coincides…

Quantum Physics · Physics 2007-05-23 Paul Vitanyi

Can a micron sized sack of interacting molecules autonomously learn an internal model of a complex and fluctuating environment? We draw insights from control theory, machine learning theory, chemical reaction network theory, and statistical…

Molecular Networks · Quantitative Biology 2023-11-08 William Poole , Thomas E. Ouldridge , Manoj Gopalkrishnan

We survey and introduce concepts and tools located at the intersection of information theory and network biology. We show that Shannon's information entropy, compressibility and algorithmic complexity quantify different local and global…

Molecular Networks · Quantitative Biology 2015-12-14 Hector Zenil , Narsis A. Kiani , Jesper Tegnér

Chemical reaction networks (CRNs) formally model chemistry in a well-mixed solution. CRNs are widely used to describe information processing occurring in natural cellular regulatory networks, and with upcoming advances in synthetic biology,…

Computational Complexity · Computer Science 2015-03-20 Ho-Lin Chen , David Doty , David Soloveichik

An algorithm is given in this paper for the computation of dynamically equivalent weakly reversible realizations with the maximal number of reactions, for chemical reaction networks (CRNs) with mass action kinetics. The original problem…

Dynamical Systems · Mathematics 2011-07-05 Gabor Szederkenyi , Katalin M. Hangos , Zsolt Tuza

One of the most fundamental problems in science is to define {\it quantitatively} the complexity of organized matters, i.e., {\it organized complexity}. Although many measures have been proposed toward this aim in previous decades, there is…

Information Theory · Computer Science 2016-08-03 Tatsuaki Okamoto

Autonomous computations that rely on automated reaction network elucidation algorithms may pave the way to make computational catalysis on a par with experimental research in the field. Several advantages of this approach are key to…

Materials Science · Physics 2022-03-18 Miguel Steiner , Markus Reiher

In this paper, we present a theoretical effort to connect the theory of program size to psychology by implementing a concrete language of thought with Turing-computable Kolmogorov complexity (LT^2C^2) satisfying the following requirements:…

Neurons and Cognition · Quantitative Biology 2013-03-06 Sergio Romano , Mariano Sigman , Santiago Figueira

There are (at least) three approaches to quantifying information. The first, algorithmic information or Kolmogorov complexity, takes events as strings and, given a universal Turing machine, quantifies the information content of a string as…

Information Theory · Computer Science 2011-11-29 David Balduzzi

Formal methods have enabled breakthroughs in many fields, such as in hardware verification, machine learning and biological systems. The key object of interest in systems biology, synthetic biology, and molecular programming is chemical…

Emerging Technologies · Computer Science 2020-08-11 Marko Vasic , David Soloveichik , Sarfraz Khurshid

Chemical reaction networks are widely used to model stochastic dynamics in chemical kinetics, systems biology and epidemiology. Solving the chemical master equation that governs these systems poses a significant challenge due to the large…

Molecular Networks · Quantitative Biology 2025-12-16 Jiayu Weng , Xinyi Zhu , Jing Liu , Linyuan Lü , Pan Zhang , Ying Tang

We present efficient and practical algorithms for a large, distributed system of processors to achieve reliable computations in a secure manner. Specifically, we address the problem of computing a general function of several private inputs…

Cryptography and Security · Computer Science 2021-01-29 Donald Rozinak Beaver

Biological regulatory networks depend upon chemical interactions to process information. Engineering such molecular computing systems is a major challenge for synthetic biology and related fields. The chemical reaction network (CRN) model…

Emerging Technologies · Computer Science 2020-09-23 Cameron Chalk , Niels Kornerup , Wyatt Reeves , David Soloveichik

Chemical Reaction Optimization (CRO) is a powerful metaheuristic which mimics the interactions of molecules in chemical reactions to search for the global optimum. The perturbation function greatly influences the performance of CRO on…

Neural and Evolutionary Computing · Computer Science 2015-02-03 James J. Q. Yu , Albert Y. S. Lam , Victor O. K. Li

For a simple model of mutually interacting qubits it is shown how the errors induced by mutual interactions can be eliminated using concatenated coding. The model is solved exactly for arbitrary interaction strength, for two well-known…

Quantum Physics · Physics 2009-11-06 Julio Gea-Banacloche

Molecular recognition, which is essential in processing information in biological systems, takes place in a crowded noisy biochemical environment and requires the recognition of a specific target within a background of various similar…

Biomolecules · Quantitative Biology 2010-07-27 Yonatan Savir , Tsvi Tlusty

Efficient and accurate decoding of quantum error-correcting codes is essential for fault-tolerant quantum computation, however, it is challenging due to the degeneracy of errors, the complex code topology, and the large space for logical…

Quantum Physics · Physics 2025-03-28 Hanyan Cao , Feng Pan , Dongyang Feng , Yijia Wang , Pan Zhang

Stochasticity is a key characteristic of intracellular processes such as gene regulation and chemical signalling. Therefore, characterising stochastic effects in biochemical systems is essential to understand the complex dynamics of living…

Molecular Networks · Quantitative Biology 2019-03-04 David J. Warne , Ruth E. Baker , Matthew J. Simpson
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