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Transmission optical coherence tomography (OCT) enables analysis of biological specimens in vitro through detection of forward scattered light. Up to now, transmission OCT was considered as a technique that cannot directly retrieve…

Optics · Physics 2024-05-24 Wojciech Krauze , Martyna Mazur , Arkadiusz Kuś

This paper reports on advances in optical coherence tomography (OCT) for application in dermatology. Full-field OCT is a particular approach of OCT based on white-light interference microscopy. FF-OCT produces en face tomographic images by…

Medical Physics · Physics 2018-04-06 Olivier Levecq , Arthur Davis , Hicham Azimani , David Siret , Jean-Luc Perrot , Arnaud Dubois

There is an increasing need for label free methods that could reveal intracellular structures and dynamics. In this context, we develop a new optical tomography method working in transmission - Full-field optical transmission tomography…

Optical coherence tomography (OCT) uses low-coherence reflectometry to obtain cross-sectional images of inhomogeneous media, such as biological tissue. OCT is particularly useful in the biomedical ea, since the imaging can be performed…

Medical Physics · Physics 2018-03-01 Takahisa Mitsui , Kenichiro Aoki

Optical coherence tomography (OCT) is a volumetric imaging modality that empowers clinicians and scientists to noninvasively visualize the cross-sections of biological samples. As the latest generation of its kind, Fourier-domain OCT…

Image and Video Processing · Electrical Eng. & Systems 2020-05-20 Yuye Ling , Mengyuan Wang , Yu Gan , Xinwen Yao , Leopold Schmetterer , Chuanqing Zhou , Yikai Su

Traditional full-field optical coherence tomography (FF-OCT) is effective for rapid cross-sectional imaging but often suffers from incoherent signals due to imbalanced light intensities between the sample and reference arms. While the…

Optics · Physics 2024-10-17 Youlong Fan , Qingye Hu , Zhongping Wang , Zengming Zhang , Xiantao Wei

In this chapter a general mathematical model of Optical Coherence Tomography (OCT) is presented on the basis of the electromagnetic theory. OCT produces high resolution images of the inner structure of biological tissues. Images are…

Numerical Analysis · Mathematics 2016-04-19 Peter Elbau , Leonidas Mindrinos , Otmar Scherzer

Imaging airway tissue, optical coherence tomography (OCT) provides cross-sectional images of tissue structures, shows cilia movement and mucus secretion, but does not provide sufficient contrast to differentiate individual cells. By using…

We report on a theoretical model for image formation in full-field optical coherence tomography (FFOCT). Because the spatial incoherence of the illumination acts as a virtual confocal pinhole in FFOCT, its imaging performance is equivalent…

Optical Coherence Tomography (OCT) has become an indispensable tool for investigating mesoscopic features in soft matter and fluid mechanics. Its ability to provide high-resolution, non-invasive measurements in both spatial and temporal…

While optical coherence tomography (OCT) provides a resolution down to 1 micrometer it has difficulties to visualize cellular structures due to a lack of scattering contrast. By evaluating signal fluctuations, a significant contrast…

We propose a new technique, called quantum optical coherence tomography (QOCT), for carrying out tomographic measurements with dispersion-cancelled resolution. The technique can also be used to extract the frequency-dependent refractive…

Using spectrally correlated photon pairs instead of classical laser light and coincidence detection instead of light intensity detection, Quantum Optical Coherence Tomography (Q-OCT) outperforms classical OCT in several experimental terms.…

Quantum Physics · Physics 2025-10-06 Sylwia M. Kolenderska , Crislane Vieira de Brito , Piotr Kolenderski

Optical coherence tomography (OCT) is a powerful technology for rapid volumetric imaging in biomedicine. The bright field imaging approach of conventional OCT systems is based on the detection of directly backscattered light, thereby…

This dissertation relates to the transition of the state of the art of swept source optical coherence tomography (SS-OCT) systems to a new realm in which the image acquisition speed is improved by an order of magnitude. With the aid of a…

Image and Video Processing · Electrical Eng. & Systems 2020-02-21 Amir Tofighi Zavareh

We developed a new endogenous approach to reveal subcellular metabolic contrast in fresh ex vivo tissues taking advantage of the time dependence of the full field optical coherence tomography interferometric signals. This method reveals…

Medical Physics · Physics 2016-01-07 Clement Apelian , Fabrice Harms , Olivier Thouvenin , A. Claude Boccara

A recent advance in optical coherence tomography (OCT), termed swept-source OCT, is generalized into a new technique, Fourier-domain OCT. It represents a realization of a full-field OCT system in place of the conventional serial image…

Optical coherence tomography (OCT) is a label-free, non-invasive 3D imaging tool widely used in both biological research and clinical diagnosis. Current OCT modalities can only visualize specimen tomography without chemical information.…

Optical coherence tomography (OCT) is capable of non-destructively obtaining cross-sectional information of samples with micrometer spatial resolution, which plays an important role in ophthalmology and endovascular medicine. Measuring OCT…

Medical Physics · Physics 2023-11-30 Yang Jianlong , Zhang Haoran , Liu Chang , Gu Chengfu

We present an experimental demonstration of quantum optical coherence tomography (QOCT). The technique makes use of an entangled twin-photon light source to carry out axial optical sectioning. QOCT is compared to conventional optical…

Quantum Physics · Physics 2019-10-18 Magued B. Nasr , Bahaa E. A. Saleh , Alexander V. Sergienko , Malvin C. Teich
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