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In this paper we propose a novel method for the segmentation of longitudinal brain MRI scans of patients suffering from Multiple Sclerosis. The method builds upon an existing cross-sectional method for simultaneous whole-brain and lesion…

Image and Video Processing · Electrical Eng. & Systems 2021-01-05 Stefano Cerri , Andrew Hoopes , Douglas N. Greve , Mark Mühlau , Koen Van Leemput

Medical image segmentation is critical for computer-aided diagnosis. However, dense pixel-level annotation is time-consuming and expensive, and medical datasets often exhibit severe class imbalance. Such imbalance causes minority structures…

Computer Vision and Pattern Recognition · Computer Science 2026-03-06 Yingxue Su , Yiheng Zhong , Keying Zhu , Zimu Zhang , Zhuoru Zhang , Yifang Wang , Yuxin Zhang , Jingxin Liu

Noisy labels can significantly affect the performance of deep neural networks (DNNs). In medical image segmentation tasks, annotations are error-prone due to the high demand in annotation time and in the annotators' expertise. Existing…

Image and Video Processing · Electrical Eng. & Systems 2023-08-08 Jiachen Yao , Yikai Zhang , Songzhu Zheng , Mayank Goswami , Prateek Prasanna , Chao Chen

This paper proposes a novel approach to spectral computed tomography (CT) material decomposition that uses the recent advances in generative diffusion models (DMs) for inverse problems. Spectral CT and more particularly photon-counting CT…

We investigate whether synthetic images generated by diffusion models can enhance multi-label classification of protein subcellular localization. Specifically, we implement a simplified class-conditional denoising diffusion probabilistic…

Computer Vision and Pattern Recognition · Computer Science 2025-05-30 Sylvey Lin , Zhi-Yi Cao

Remote sensing image super-resolution (SR) is a crucial task to restore high-resolution (HR) images from low-resolution (LR) observations. Recently, the Denoising Diffusion Probabilistic Model (DDPM) has shown promising performance in image…

Image and Video Processing · Electrical Eng. & Systems 2024-03-19 Jialu Sui , Xianping Ma , Xiaokang Zhang , Man-On Pun

The statistical properties of the density map (DM) approach to counting microbiological objects on images are studied in detail. The DM is given by U$^2$-Net. Two statistical methods for deep neural networks are utilized: the bootstrap and…

Computer Vision and Pattern Recognition · Computer Science 2022-07-07 Krzysztof M. Graczyk , Jaroslaw Pawlowski , Sylwia Majchrowska , Tomasz Golan

Detecting anomalies in brain MRI scans using supervised deep learning methods presents challenges due to anatomical diversity and labor-intensive requirement of pixel-level annotations. Generative models like Denoising Diffusion…

Image and Video Processing · Electrical Eng. & Systems 2024-10-01 Vivek Kumar Trivedi , Bheeshm Sharma , P. Balamurugan

The volume of a brain lesion (e.g. infarct or tumor) is a powerful indicator of patient prognosis and can be used to guide the therapeutic strategy. Lesional volume estimation is usually performed by segmentation with deep convolutional…

Image and Video Processing · Electrical Eng. & Systems 2023-07-31 Benjamin Lambert , Florence Forbes , Senan Doyle , Michel Dojat

We propose a novel and unified method, measurement-conditioned denoising diffusion probabilistic model (MC-DDPM), for under-sampled medical image reconstruction based on DDPM. Different from previous works, MC-DDPM is defined in measurement…

Image and Video Processing · Electrical Eng. & Systems 2022-03-09 Yutong Xie , Quanzheng Li

Stroke is the second leading cause of death and the third leading cause of disability worldwide. Clinical guidelines establish diffusion resonance imaging (DWI, ADC) as the standard for localizing, characterizing, and measuring infarct…

Image and Video Processing · Electrical Eng. & Systems 2025-08-27 Edgar Rangel , Fabio Martinez

Computed Tomography (CT) is commonly used to image acute ischemic stroke (AIS) patients, but its interpretation by radiologists is time-consuming and subject to inter-observer variability. Deep learning (DL) techniques can provide automated…

Image and Video Processing · Electrical Eng. & Systems 2023-10-02 Alessandro Fontanella , Wenwen Li , Grant Mair , Antreas Antoniou , Eleanor Platt , Paul Armitage , Emanuele Trucco , Joanna Wardlaw , Amos Storkey

Scanning Transmission Electron Microscopy (STEM) is a critical tool for imaging the properties of materials and biological specimens at atomic scale, yet our understanding of relevant electron beam damage mechanisms is incomplete. Recent…

Signal Processing · Electrical Eng. & Systems 2025-07-02 Amir Javadi Rad , Amirafshar Moshtaghpour , Dongdong Chen , Angus I. Kirkland

Brain midline shift (MLS) is one of the most critical factors to be considered for clinical diagnosis and treatment decision-making for intracranial hemorrhage. Existing computational methods on MLS quantification not only require intensive…

Computer Vision and Pattern Recognition · Computer Science 2023-01-03 Shizhan Gong , Cheng Chen , Yuqi Gong , Nga Yan Chan , Wenao Ma , Calvin Hoi-Kwan Mak , Jill Abrigo , Qi Dou

Recent advances in deep learning algorithms have led to significant benefits for solving many medical image analysis problems. Training deep learning models commonly requires large datasets with expert-labeled annotations. However,…

Computer Vision and Pattern Recognition · Computer Science 2023-09-19 Banafshe Felfeliyan , Abhilash Hareendranathan , Gregor Kuntze , Stephanie Wichuk , Nils D. Forkert , Jacob L. Jaremko , Janet L. Ronsky

Accelerated MRI reconstruction plays a vital role in reducing scan time while preserving image quality. While most existing methods rely on complex-valued image-space or k-space data, these formats are often inaccessible in clinical…

Image and Video Processing · Electrical Eng. & Systems 2025-04-29 Tao Song , Yicheng Wu , Minhao Hu , Xiangde Luo , Guoting Luo , Guotai Wang , Yi Guo , Feng Xu , Shaoting Zhang

At present, the majority of the proposed Deep Learning (DL) methods provide point predictions without quantifying the models uncertainty. However, a quantification of the reliability of automated image analysis is essential, in particular…

Image and Video Processing · Electrical Eng. & Systems 2020-08-17 Lisa Herzog , Elvis Murina , Oliver Dürr , Susanne Wegener , Beate Sick

Recent advancements in diffusion probabilistic models (DPMs) have revolutionized image processing, demonstrating significant potential in medical applications. Accurate segmentation of the left ventricle (LV) in echocardiograms is crucial…

Computer Vision and Pattern Recognition · Computer Science 2025-06-19 Abdur Rahman , Keerthiveena Balraj , Manojkumar Ramteke , Anurag Singh Rathore

Despite the ever-increasing interest in applying deep learning (DL) models to medical imaging, the typical scarcity and imbalance of medical datasets can severely impact the performance of DL models. The generation of synthetic data that…

Image and Video Processing · Electrical Eng. & Systems 2023-04-03 Pouria Rouzrokh , Bardia Khosravi , Shahriar Faghani , Mana Moassefi , Sanaz Vahdati , Bradley J. Erickson

Denoising Diffusion Probabilistic Models (DDPMs) represent a contemporary class of generative models with exceptional qualities in both synthesis and maximizing the data likelihood. These models work by traversing a forward Markov Chain…

Machine Learning · Computer Science 2024-09-16 Hang Li , Wei Jin , Geri Skenderi , Harry Shomer , Wenzhuo Tang , Wenqi Fan , Jiliang Tang