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Score-based diffusion models, which generate new data by learning to reverse a diffusion process that perturbs data from the target distribution into noise, have achieved remarkable success across various generative tasks. Despite their…

Machine Learning · Computer Science 2025-01-23 Gen Li , Yuling Yan

In recent years, computational pathology has seen tremendous progress driven by deep learning methods in segmentation and classification tasks aiding prognostic and diagnostic settings. Nuclei segmentation, for instance, is an important…

Image and Video Processing · Electrical Eng. & Systems 2023-03-22 Aman Shrivastava , P. Thomas Fletcher

Deep learning and generative models are advancing rapidly, with synthetic data increasingly being integrated into training pipelines for downstream analysis tasks. However, in medical imaging, their adoption remains constrained by the…

Computer Vision and Pattern Recognition · Computer Science 2026-03-26 Kyeonghun Kim , Jaehyeok Bae , Youngung Han , Joo Young Bae , Seoyoung Ju , Junsu Lim , Gyeongmin Kim , Nam-Joon Kim , Woo Kyoung Jeong , Ken Ying-Kai Liao , Won Jae Lee , Pa Hong , Hyuk-Jae Lee

Accurate stroke lesion segmentation plays a pivotal role in stroke rehabilitation research, to provide lesion shape and size information which can be used for quantification of the extent of the stroke and to assess treatment efficacy.…

Image and Video Processing · Electrical Eng. & Systems 2022-11-29 Jiayu Huo , Liyun Chen , Yang Liu , Maxence Boels , Alejandro Granados , Sebastien Ourselin , Rachel Sparks

Efficient and accurate whole-brain lesion segmentation remains a challenge in medical image analysis. In this work, we revisit MeshNet, a parameter-efficient segmentation model, and introduce a novel multi-scale dilation pattern with an…

Image and Video Processing · Electrical Eng. & Systems 2025-03-10 Alex Fedorov , Yutong Bu , Xiao Hu , Chris Rorden , Sergey Plis

Accurate segmentation of Multiple Sclerosis (MS) lesions in longitudinal MRI scans is crucial for monitoring disease progression and treatment efficacy. Although changes across time are taken into account when assessing images in clinical…

The existing barely-supervised medical image segmentation (BSS) methods, adopting a registration-segmentation paradigm, aim to learn from data with very few annotations to mitigate the extreme label scarcity problem. However, this paradigm…

Computer Vision and Pattern Recognition · Computer Science 2024-07-09 Junming Su , Zhiqiang Shen , Peng Cao , Jinzhu Yang , Osmar R. Zaiane

Data limitation is a significant challenge in applying deep learning to medical images. Recently, the diffusion probabilistic model (DPM) has shown the potential to generate high-quality images by converting Gaussian random noise into…

Computer Vision and Pattern Recognition · Computer Science 2024-08-26 Sepehr Salem Ghahfarokhi , Tyrell To , Julie Jorns , Tina Yen , Bing Yu , Dong Hye Ye

Semi-supervised learning (SSL) is a promising machine learning paradigm to address the issue of label scarcity in medical imaging. SSL methods were originally developed in image classification. The state-of-the-art SSL methods in image…

Computer Vision and Pattern Recognition · Computer Science 2023-05-03 Mou-Cheng Xu , Yukun Zhou , Chen Jin , Marius De Groot , Neil P. Oxtoby , Daniel C. Alexander , Joseph Jacob

Denoising Diffusion Probabilistic Models (DDPMs) can generate high-quality samples such as image and audio samples. However, DDPMs require hundreds to thousands of iterations to produce final samples. Several prior works have successfully…

Computer Vision and Pattern Recognition · Computer Science 2022-11-01 Luping Liu , Yi Ren , Zhijie Lin , Zhou Zhao

Accurate detection and segmentation of brain tumors in magnetic resonance imaging (MRI) are critical for effective diagnosis and treatment planning. Despite advances in convolutional neural networks (CNNs) such as U-Net, existing models…

Computer Vision and Pattern Recognition · Computer Science 2025-10-14 Sashank Makanaboyina

Sequential whole-body 18F-Fluorodeoxyglucose (FDG) positron emission tomography (PET) scans are regarded as the imaging modality of choice for the assessment of treatment response in the lymphomas because they detect treatment response when…

Image and Video Processing · Electrical Eng. & Systems 2021-06-10 Kai-Chieh Liang , Lei Bi , Ashnil Kumar , Michael Fulham , Jinman Kim

Existing segmentation models trained on a single medical imaging dataset often lack robustness when encountering unseen organs or tumors. Developing a robust model capable of identifying rare or novel tumor categories not present during…

Computer Vision and Pattern Recognition · Computer Science 2025-07-02 Rong Wu , Ziqi Chen , Liming Zhong , Heng Li , Hai Shu

Remote sensing change detection is crucial for understanding the dynamics of our planet's surface, facilitating the monitoring of environmental changes, evaluating human impact, predicting future trends, and supporting decision-making. In…

Computer Vision and Pattern Recognition · Computer Science 2024-01-15 Wele Gedara Chaminda Bandara , Nithin Gopalakrishnan Nair , Vishal M. Patel

Weakly supervised semantic segmentation (WSSS) methods using class labels often rely on class activation maps (CAMs) to localize objects. However, traditional CAM-based methods struggle with partial activations and imprecise object…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Dewen Zeng , Xinrong Hu , Yu-Jen Chen , Yawen Wu , Xiaowei Xu , Yiyu Shi

Stepwise signals are ubiquitous in single-molecule detections, where abrupt changes in signal levels typically correspond to molecular conformational changes or state transitions. However, these features are inevitably obscured by noise,…

Signal Processing · Electrical Eng. & Systems 2026-02-10 Xingdi Tong , Chenyu Wen

It has always been a big challenge to identify subtle changes in Electroencephalogram (EEG) signals. Minor differences often lead to vital decisions, for example, which grade a certain tumour belong to or whether a haemorrhage can result in…

Systems and Control · Electrical Eng. & Systems 2022-06-01 Debojyoti Seth

The instability is shown in the existing methods of representation learning based on Euclidean distance under a broad set of conditions. Furthermore, the scarcity and high cost of labels prompt us to explore more expressive representation…

Machine Learning · Computer Science 2021-10-07 Jielei Chu , Jing Liu , Hongjun Wang , Meng Hua , Zhiguo Gong , Tianrui Li

Segmentation of lymphoma lesions is challenging due to their varied sizes and locations in whole-body PET scans. This work presents a fully-automated segmentation technique using a multi-center dataset of diffuse large B-cell lymphoma…

The soft Dice loss (SDL) has taken a pivotal role in numerous automated segmentation pipelines in the medical imaging community. Over the last years, some reasons behind its superior functioning have been uncovered and further optimizations…

Computer Vision and Pattern Recognition · Computer Science 2024-03-21 Zifu Wang , Teodora Popordanoska , Jeroen Bertels , Robin Lemmens , Matthew B. Blaschko
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