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DNA amplification is the process of replication of a specified DNA sequence \emph{in vitro} through time-dependent manipulation of its external environment. A theoretical framework for determination of the optimal dynamic operating…

Biological Physics · Physics 2015-06-23 Karthikeyan Marimuthu , Raj Chakrabarti

Despite their topological complexity almost all functional properties of metabolic networks can be derived from steady-state dynamics. Indeed, many theoretical investigations (like flux-balance analysis) rely on extracting function from…

Molecular Networks · Quantitative Biology 2009-11-13 Carsten Marr , Mark Mueller-Linow , Marc-Thorsten Huett

We present a protocol for the study of the dynamics and thermodynamics of quantum systems strongly coupled to a bath and subject to an external modulation. Our protocol quantifies the evolution of the system-bath composite by expanding the…

Statistical Mechanics · Physics 2018-10-24 Wenjie Dou , Maicol A. Ochoa , Abraham Nitzan , Joseph E. Subotnik

For multilayer materials in thin substrate systems, interfacial failure is one of the most challenges. The traction-separation relations (TSR) quantitatively describe the mechanical behavior of a material interface undergoing openings,…

Computational Engineering, Finance, and Science · Computer Science 2020-12-01 Jiaxin Zhang , Congjie Wei , Chenglin Wu

Power law dynamics is used to describe the stability behavior in metabolic networks such as chemical reaction networks (CRN's). These systems allow multiple steady states within a single stoichiometric class. On the other side thermodynamic…

Dynamical Systems · Mathematics 2020-07-10 Gunther Friedrich Neumann

The dynamics of Boolean networks (BN) with quenched disorder and thermal noise is studied via the generating functional method. A general formulation, suitable for BN with any distribution of Boolean functions, is developed. It provides…

Disordered Systems and Neural Networks · Physics 2015-05-27 Alexander Mozeika , David Saad

Numerical computations have become a pillar of all modern quantitative sciences. Any computation involves modeling--even if often this step is not made explicit--and any model has to neglect details while still being physically accurate.…

Statistical Mechanics · Physics 2022-11-08 Thomas Speck

Quantitative studies of cell metabolism are often based on large chemical reaction network models. A steady state approach is suited to analyze phenomena on the timescale of cell growth and circumvents the problem of incomplete experimental…

Molecular Networks · Quantitative Biology 2019-02-20 A. De Martino , D. De Martino , E. Marinari

A number of successful theoretical models of hardness have been developed recently. A thermodynamic model of hardness, which supposes the intrinsic character of correlation between hardness and thermodynamic properties of solids, allows one…

Materials Science · Physics 2018-04-20 V. A. Mukhanov , O. O. Kurakevych , V. L. Solozhenko

In the development of equations of state for polyatomic molecules, thermodynamic perturbation theory (TPT) is widely used to calculate the change in free energy due to chain formation. TPT is a simplification of a more general and exact…

Soft Condensed Matter · Physics 2016-07-13 Bennett D. Marshall

We investigate the thermoelectric response of single-molecule junctions composed of acyclic cross-conjugated molecules, including dendralene analogues and related iso-poly(diacetylene) (iso-PDA) motifs, in which node-possessing repeat units…

Mesoscale and Nanoscale Physics · Physics 2025-10-10 Justin P. Bergfield

A great many observables seen in intermediate energy heavy ion collisions can be explained on the basis of statistical equilibrium. Calculations based on statistical equilibrium can be implemented in microcanonical ensemble (energy and…

Nuclear Theory · Physics 2009-11-10 C. B. Das , S. Das Gupta , W. G. Lynch , A. Z. Mekjian , M. B. Tsang

Tensor-based modulation (TBM) provides a multi-linear spreading framework for blind multi-user separation in unsourced random access. In this paper, we show that TBM is a coded modulation built on a non-binary linear block code over…

Information Theory · Computer Science 2026-03-10 Sweta Suresh , Charly Poulliat , Claire Goursaud , Maxime Guillaud

In living systems, collective molecular behavior is driven by thermodynamic forces in the form of chemical gradients. Leveraging recent advances in the field of nonequilibrium physics, I show that increasing the thermodynamic force alone…

Subcellular Processes · Quantitative Biology 2022-09-21 Milo M. Lin

Modern thermodynamic theories can be used to study highly complex quantum dynamics. Here, we experimentally demonstrate that the violation of thermodynamic constraints allows to detect the coupling of a quantum system to a hidden…

Quantum Physics · Physics 2021-03-10 Ivan Henao , Raam Uzdin , Nadav Katz

We present the molecular hyperdynamics algorithm and its implementation to the nonorthogonal tight-binding model NTBM and the corresponding software. Due to its multiscale structure, the proposed approach provides the long time scale…

Equilibrating proteins and other biomacromolecules is cardinal for molecular dynamics simulation of such biological systems in which they perform free dynamics without any externally-applied mechanical constraint, until thermodynamic…

Soft Condensed Matter · Physics 2021-02-11 Ashkan Shekaari , Mahmoud Jafari

We investigate the thermodynamic properties of a Restricted Boltzmann Machine (RBM), a simple energy-based generative model used in the context of unsupervised learning. Assuming the information content of this model to be mainly reflected…

Disordered Systems and Neural Networks · Physics 2018-08-20 Aurélien Decelle , Giancarlo Fissore , Cyril Furtlehner

Complex molecules and mesoscopic structures are naturally described by general networks of elementary building blocks and tight-binding is one of the simplest quantum model suitable for studying the physical properties arising from the…

Condensed Matter · Physics 2009-11-07 P. Buonsante , R. Burioni , D. Cassi

The ATLAS experiment at the Large Hadron Collider explores the use of modern neural networks for a multi-dimensional calibration of its calorimeter signal defined by clusters of topologically connected cells (topo-clusters). The Bayesian…

High Energy Physics - Experiment · Physics 2026-02-03 ATLAS Collaboration