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Understanding the emergent behavior of chemical reaction networks (CRNs) is a fundamental aspect of biology and its origin from inanimate matter. A closed CRN monotonically tends to thermal equilibrium, but when it is opened to external…

Molecular Networks · Quantitative Biology 2024-05-16 Masanari Shimada , Pegah Behrad , Eric De Giuli

We analyze the thermodynamic properties of a simplified model for folded RNA molecules recently studied by G. Vernizzi, H. Orland, A. Zee (in {\it Phys. Rev. Lett.} {\bf 94} (2005) 168103). The model consists of a chain of one-flavor base…

Biomolecules · Quantitative Biology 2009-11-13 Matias dell'Erba , Guillermo R. Zemba

The connection between entanglement dynamics and non-equilibrium statistics in isolated many-body quantum systems has been established both theoretically and experimentally. Many-Body Localization (MBL), a phenomenon where interacting…

Quantum Physics · Physics 2025-07-04 Peyman Azodi , Herschel A. Rabitz

Thermodynamic simulation of chemical and metallurgical systems is the only method to predict their equilibrium composition and is the most important application of chemical thermodynamics. The conventional strategy of simulation is always…

Chemical Physics · Physics 2007-05-23 B. Zilbergleyt

Water management is one of the most critical aspects of our society, together with population increase and climate change. Water scarcity requires a better characterization and monitoring of Water Distribution Networks (WDNs). This paper…

Signal Processing · Electrical Eng. & Systems 2025-05-13 Tiziana Cattai , Stefania Sardellitti , Stefania Colonnese , Francesca Cuomo , Sergio Barbarossa

When we consider canonical average for classical discrete systems under constant composition (specifically, substitutional alloys) as a map phi from a set of many-body interatomic interactions to that of microscopic configuration in…

Statistical Mechanics · Physics 2025-05-12 Ryu Tomitaka , Koretaka Yuge

Thermalization is a ubiquitous process of statistical physics, in which details of few-body observables are washed out in favor of a featureless steady state. Even in isolated quantum many-body systems, limited to reversible dynamics,…

Quantum Physics · Physics 2022-05-19 W. Morong , F. Liu , P. Becker , K. S. Collins , L. Feng , A. Kyprianidis , G. Pagano , T. You , A. V. Gorshkov , C. Monroe

Thermal boundary conductance (TBC) is critical in many thermal and energy applications. A decades-old puzzle has been that many of the measured TBCs, such as those well characterized across Al/Si and ZnO/GaN interfaces, significantly exceed…

Mesoscale and Nanoscale Physics · Physics 2019-04-16 Jingjing Shi , Xiaolong Yang , Timothy S. Fisher , Xiulin Ruan

Understanding how protein mutations affect protein-nucleic acid binding is critical for unraveling disease mechanisms and advancing therapies. Current experimental approaches are laborious, and computational methods remain limited in…

Quantitative Methods · Quantitative Biology 2025-05-30 Xiang Liu , Junjie Wee , Guo-Wei Wei

Exact and approximate expressions for thermodynamic characteristics of heated matter, which consists of particles with finite mass-widths, are constructed. They are expressed in terms of Fermi/Bose distributions and spectral functions,…

Nuclear Theory · Physics 2008-11-26 D. N. Voskresensky

The deep connection between thermodynamics, computation, and information is now well established both theoretically and experimentally. Here, we extend these ideas to show that thermodynamics also places fundamental constraints on…

Biological Physics · Physics 2014-10-08 Alex H. Lang , Charles K. Fisher , Thierry Mora , Pankaj Mehta

Interactions between biomolecules, electrons and protons are essential to many fundamental processes sustaining life. It is therefore of interest to build mathematical models of these bioelectrical processes not only to enhance…

Molecular Networks · Quantitative Biology 2020-12-08 Peter J. Gawthrop , Michael Pan

Molecular communication (MC) is a promising paradigm for applications where traditional electromagnetic communications are impractical. However, decoding chemical signals, especially in multi-transmitter systems, remains a key challenge due…

Signal Processing · Electrical Eng. & Systems 2025-11-05 Vivien Walter , Dadi Bi , Daniel L. Ruiz Blanco , Yansha Deng

From the crystal structure data and using the concept of equilbrium statistical mechanics we show how to calculate the thermodynamics of protein/DNA complexes. We apply the method to the TATA-box binding protein (TBP)/TATA sequence complex.…

Biological Physics · Physics 2007-05-23 Sudipta Samanta , J. Chakrabarti , Dhananjay Bhattacharyya

Due to inter-subunit communication, multisubunit enzymes usually hydrolyze ATP in a concerted fashion. However, so far the principle of this process remains poorly understood. In this study, from the viewpoint of statistical thermodynamics,…

Mathematical Physics · Physics 2015-06-04 Yunxin Zhang

Due to its non-crystalline nature, the glassy state has remained one the most exciting scientific challenges. To study such materials, Molecular Dynamics (MD) simulations have been extensively used because they provide a direct view into…

Materials Science · Physics 2015-06-23 Mathieu Bauchy

Ultra-precision machining of metals, the breaking of nanowires under tensile stress and fracture of nanoscale materials are examples of technologically important processes which are both extremely difficult and costly to investigate…

Materials Science · Physics 2007-05-23 Maciej Bobrowski , Jacek Dziedzic , Jaroslaw Rybicki

RNA function crucially depends on its structure. Thermodynamic models currently used for secondary structure prediction rely on computing the partition function of folding ensembles, and can thus estimate minimum free-energy structures and…

Biomolecules · Quantitative Biology 2022-07-26 Nicola Calonaci , Alisha Jones , Francesca Cuturello , Michael Sattler , Giovanni Bussi

Thermodynamics with internal variables is a common approach in continuum mechanics to model inelastic (i.e., non-equilibrium) material behavior. While this approach is computationally and theoretically attractive, it currently lacks a…

Statistical Mechanics · Physics 2025-01-31 Weilun Qiu , Shenglin Huang , Celia Reina

Chemical space is routinely explored by machine learning methods to discover interesting molecules, before time-consuming experimental synthesizing is attempted. However, these methods often rely on a graph representation, ignoring 3D…