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We demonstrate the ability of statistical data assimilation to identify the measurements required for accurate state and parameter estimation in an epidemiological model for the novel coronavirus disease COVID-19. Our context is an effort…

Populations and Evolution · Quantitative Biology 2020-08-04 Eve Armstrong , Manuela Runge , Jaline Gerardin

We propose a robust parameter estimation method for dynamical systems based on Statistical Learning techniques which aims to estimate a set of parameters that well fit the dynamics in order to obtain robust evidences about the qualitative…

Methodology · Statistics 2021-02-26 Diego Marcondes

Accurate prediction of contagious disease outbreaks is vital for informed decision-making. Our study addresses the gap between machine learning algorithms and their epidemiological applications, noting that methods optimal for benchmark…

Machine Learning · Computer Science 2025-06-16 Suhan Guo , Zhenghao Xu , Furao Shen , Jian Zhao

To better predict the dynamics of epidemics such as COVID-19, it is important not only to investigate the network of local and long-range contagious contacts but also to understand the temporal dynamics of infectiousness and detectable…

Populations and Evolution · Quantitative Biology 2025-09-03 Miguel A. Cajahuanca Ricaldi , Yaroslav Ispolatov

The COVID-19 pandemic has emphasized the need for a robust understanding of epidemic models. Current models of epidemics are classified as either mechanistic or non-mechanistic: mechanistic models make explicit assumptions on the dynamics…

Machine Learning · Statistics 2022-01-14 Arnab Sarker , Ali Jadbabaie , Devavrat Shah

Accurate forecasts of the number of newly infected people during an epidemic are critical for making effective timely decisions. This paper addresses this challenge using the SIMLR model, which incorporates machine learning (ML) into the…

Machine Learning · Computer Science 2021-06-04 Roberto Vega , Leonardo Flores , Russell Greiner

The COVID-19 pandemic represents the most significant public health disaster since the 1918 influenza pandemic. During pandemics such as COVID-19, timely and reliable spatio-temporal forecasting of epidemic dynamics is crucial. Deep…

Machine Learning · Computer Science 2020-11-25 Lijing Wang , Aniruddha Adiga , Srinivasan Venkatramanan , Jiangzhuo Chen , Bryan Lewis , Madhav Marathe

Cyber-physical systems often consist of entities that interact with each other over time. Meanwhile, as part of the continued digitization of industrial processes, various sensor technologies are deployed that enable us to record…

Machine Learning · Computer Science 2018-09-03 Razvan-Gabriel Cirstea , Darius-Valer Micu , Gabriel-Marcel Muresan , Chenjuan Guo , Bin Yang

This paper presents a novel approach to epidemic surveillance, leveraging the power of Artificial Intelligence and Large Language Models (LLMs) for effective interpretation of unstructured big data sources, like the popular ProMED and WHO…

Computational Engineering, Finance, and Science · Computer Science 2024-08-27 Sergio Consoli , Peter Markov , Nikolaos I. Stilianakis , Lorenzo Bertolini , Antonio Puertas Gallardo , Mario Ceresa

The recent COVID-19 pandemic has thrown the importance of accurately forecasting contagion dynamics and learning infection parameters into sharp focus. At the same time, effective policy-making requires knowledge of the uncertainty on such…

Machine Learning · Computer Science 2025-07-04 Thomas Gaskin , Tim Conrad , Grigorios A. Pavliotis , Christof Schütte

Epidemic modeling is an essential tool to understand the spread of the novel coronavirus and ultimately assist in disease prevention, policymaking, and resource allocation. In this article, we establish a state of the art interface between…

Applications · Statistics 2020-12-17 Li Wang , Guannan Wang , Lei Gao , Xinyi Li , Shan Yu , Myungjin Kim , Yueying Wang , Zhiling Gu

Forecasting infectious disease outbreaks is hard. Forecasting emerging infectious diseases with limited historical data is even harder. In this paper, we investigate ways to improve emerging infectious disease forecasting under operational…

A plethora of prediction models of SARS-CoV-2 pandemic were proposed in the past. Prediction performances not only depend on the structure and features of the model, but also on its parametrization. Official databases are often biased due…

Populations and Evolution · Quantitative Biology 2021-09-27 Yuri Kheifetz , Holger Kirsten , Markus Scholz

A prompt public health response to a new epidemic relies on the ability to monitor and predict its evolution in real time as data accumulate. The 2009 A/H1N1 outbreak in the UK revealed pandemic data as noisy, contaminated, potentially…

Health-policy planning requires evidence on the burden that epidemics place on healthcare systems. Multiple, often dependent, datasets provide a noisy and fragmented signal from the unobserved epidemic process including transmission and…

Applications · Statistics 2024-09-11 Alice Corbella , Anne M Presanis , Paul J Birrell , Daniela De Angelis

Many problems in the geophysical sciences demand the ability to calibrate the parameters and predict the time evolution of complex dynamical models using sequentially-collected data. Here we introduce a general methodology for the joint…

Computation · Statistics 2018-12-12 Sara Pérez-Vieites , Inés P. Mariño , Joaquín Míguez

Computational models have become a powerful tool in the quantitative sciences to understand the behaviour of complex systems that evolve in time. However, they often contain a potentially large number of free parameters whose values cannot…

Optimization and Control · Mathematics 2023-02-13 Thomas Gaskin , Grigorios A. Pavliotis , Mark Girolami

The recent outbreak of COVID-19 has affected millions of individuals around the world and has posed a significant challenge to global healthcare. From the early days of the pandemic, it became clear that it is highly contagious and that…

Social and Information Networks · Computer Science 2021-04-13 George Panagopoulos , Giannis Nikolentzos , Michalis Vazirgiannis

In realistic scenarios, multivariate timeseries evolve over case-by-case time-scales. This is particularly clear in medicine, where the rate of clinical events varies by ward, patient, and application. Increasingly complex models have been…

Machine Learning · Computer Science 2020-03-06 Jacob Deasy , Ari Ercole , Pietro Liò

We investigate ensembling techniques in forecasting and examine their potential for use in nonseasonal time-series similar to those in the early days of the COVID-19 pandemic. Developing improved forecast methods is essential as they…

Machine Learning · Computer Science 2022-01-04 Pieter Cawood , Terence L. van Zyl