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Deep learning has become a popular tool for medical image analysis, but the limited availability of training data remains a major challenge, particularly in the medical field where data acquisition can be costly and subject to privacy…

Image and Video Processing · Electrical Eng. & Systems 2024-06-11 Aghiles Kebaili , Jérôme Lapuyade-Lahorgue , Su Ruan

Diffusion models have shown an impressive ability to model complex data distributions, with several key advantages over GANs, such as stable training, better coverage of the training distribution's modes, and the ability to solve inverse…

Computer Vision and Pattern Recognition · Computer Science 2024-06-12 Yinbo Chen , Oliver Wang , Richard Zhang , Eli Shechtman , Xiaolong Wang , Michael Gharbi

Temporal volume images with 3D+t (4D) information are often used in medical imaging to statistically analyze temporal dynamics or capture disease progression. Although deep-learning-based generative models for natural images have been…

Image and Video Processing · Electrical Eng. & Systems 2022-06-28 Boah Kim , Jong Chul Ye

Deep generative modeling has emerged as a powerful tool for synthesizing realistic medical images, driving advances in medical image analysis, disease diagnosis, and treatment planning. This chapter explores various deep generative models…

Image and Video Processing · Electrical Eng. & Systems 2024-10-24 Paul Friedrich , Yannik Frisch , Philippe C. Cattin

Diffusion generative models have emerged as a powerful framework for addressing problems in structural biology and structure-based drug design. These models operate directly on 3D molecular structures. Due to the unfavorable scaling of…

Biomolecules · Quantitative Biology 2024-05-10 Ian Dunn , David Ryan Koes

Deep learning algorithms require extensive data to achieve robust performance. However, data availability is often restricted in the medical domain due to patient privacy concerns. Synthetic data presents a possible solution to these…

Diffusion models have shown strong performance in generating high-quality tabular data, but they carry privacy risks by reproducing exact training samples. While prior work focuses on dataset-level augmentation to reduce memorization,…

Machine Learning · Computer Science 2026-05-26 Zhengyu Fang , Zhimeng Jiang , Huiyuan Chen , Xiaoge Zhang , Kaiyu Tang , Xiao Li , Jing Li

Generative AI has seen remarkable growth over the past few years, with diffusion models being state-of-the-art for image generation. This study investigates the use of diffusion models in generating artificial data generation for electronic…

Machine Learning · Computer Science 2023-10-18 Prasha Srivastava , Pawan Kumar , Zia Abbas

Latent Video Diffusion Models can easily deceive casual observers and domain experts alike thanks to the produced image quality and temporal consistency. Beyond entertainment, this creates opportunities around safe data sharing of fully…

Computer Vision and Pattern Recognition · Computer Science 2024-12-13 Mischa Dombrowski , Hadrien Reynaud , Bernhard Kainz

In this study we develop dimension-reduction techniques to accelerate diffusion model inference in the context of synthetic data generation. The idea is to integrate compressed sensing into diffusion models (hence, CSDM): First, compress…

Machine Learning · Statistics 2025-09-30 Zhengyi Guo , Jiatu Li , Wenpin Tang , David D. Yao

Latent diffusion models (LDMs) dominate high-quality image generation, yet integrating representation learning with generative modeling remains a challenge. We introduce a novel generative image modeling framework that seamlessly bridges…

Computer Vision and Pattern Recognition · Computer Science 2026-01-23 Theodoros Kouzelis , Efstathios Karypidis , Ioannis Kakogeorgiou , Spyros Gidaris , Nikos Komodakis

This paper introduces an innovative methodology for producing high-quality 3D lung CT images guided by textual information. While diffusion-based generative models are increasingly used in medical imaging, current state-of-the-art…

Image and Video Processing · Electrical Eng. & Systems 2024-10-16 Yanwu Xu , Li Sun , Wei Peng , Shuyue Jia , Katelyn Morrison , Adam Perer , Afrooz Zandifar , Shyam Visweswaran , Motahhare Eslami , Kayhan Batmanghelich

Latent diffusion models achieve state-of-the-art performance on a variety of generative tasks, such as image synthesis and image editing. However, the robustness of latent diffusion models is not well studied. Previous works only focus on…

Computer Vision and Pattern Recognition · Computer Science 2023-06-16 Jianping Zhang , Zhuoer Xu , Shiwen Cui , Changhua Meng , Weibin Wu , Michael R. Lyu

This position paper argues that understanding generalization in diffusion models requires fundamentally new theoretical frameworks that go beyond both classical statistical learning theory and the benign overfitting paradigm developed for…

Machine Learning · Computer Science 2026-05-08 Pierre Marion , Yu-Han Wu

The latent space of diffusion model mostly still remains unexplored, despite its great success and potential in the field of generative modeling. In fact, the latent space of existing diffusion models are entangled, with a distorted mapping…

Machine Learning · Computer Science 2024-07-17 Jaehoon Hahm , Junho Lee , Sunghyun Kim , Joonseok Lee

Recent work has shown improved lesion detectability and flexibility to reconstruction hyperparameters (e.g. scanner geometry or dose level) when PET images are reconstructed by leveraging pre-trained diffusion models. Such methods train a…

Medical Physics · Physics 2025-08-28 George Webber , Alexander Hammers , Andrew P. King , Andrew J. Reader

Current volumetric biomedical foundation models struggle to generalize as public 3D datasets are small and do not cover the broad diversity of medical procedures, conditions, anatomical regions, and imaging protocols. We address this by…

Computer Vision and Pattern Recognition · Computer Science 2025-03-04 Neel Dey , Benjamin Billot , Hallee E. Wong , Clinton J. Wang , Mengwei Ren , P. Ellen Grant , Adrian V. Dalca , Polina Golland

Face recognition models are trained on large-scale datasets, which have privacy and ethical concerns. Lately, the use of synthetic data to complement or replace genuine data for the training of face recognition models has been proposed.…

Computer Vision and Pattern Recognition · Computer Science 2025-06-10 David Geissbühler , Hatef Otroshi Shahreza , Sébastien Marcel

Fashionable image generation aims to synthesize images of diverse fashion prevalent around the globe, helping fashion designers in real-time visualization by giving them a basic customized structure of how a specific design preference would…

Computer Vision and Pattern Recognition · Computer Science 2023-06-14 Krishna Sri Ipsit Mantri , Nevasini Sasikumar

n this work, we propose a latent molecular diffusion model that can make the generated 3D molecules rich in diversity and maintain rich geometric features. The model captures the information of the forces and local constraints between atoms…

Machine Learning · Computer Science 2024-12-06 Xiang Chen