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Generative data augmentation with latent diffusion models is a promising strategy for addressing class imbalance in medical imaging, yet current approaches focus on perceptual fidelity and domain-specific autoencoder fine-tuning while…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Mischa Dombrowski , Felix Nützel , Bernhard Kainz

While hundreds of artificial intelligence (AI) algorithms are now approved or cleared by the US Food and Drugs Administration (FDA), many studies have shown inconsistent generalization or latent bias, particularly for underrepresented…

Computer Vision and Pattern Recognition · Computer Science 2023-08-25 Luke W. Sagers , James A. Diao , Luke Melas-Kyriazi , Matthew Groh , Pranav Rajpurkar , Adewole S. Adamson , Veronica Rotemberg , Roxana Daneshjou , Arjun K. Manrai

Generative neural networks learn how to produce highly realistic images from a large, but finite number of examples - or do they simply memorise their training set? To settle this question, Kadkhodaie, Guth, Simoncelli and Mallat (ICLR '24)…

Machine Learning · Statistics 2026-05-21 Antoine Maillard , Sebastian Goldt

The scarcity of publicly available medical imaging data limits the development of effective AI models. This work proposes a memory-efficient patch-wise denoising diffusion probabilistic model (DDPM) for generating synthetic medical images,…

Image and Video Processing · Electrical Eng. & Systems 2024-10-17 Kathrin Khadra , Utku Türkbey

Acquiring large quantities of data and annotations is known to be effective for developing high-performing deep learning models, but is difficult and expensive to do in the healthcare context. Adding synthetic training data using generative…

Image and Video Processing · Electrical Eng. & Systems 2023-10-06 Menghan Yu , Sourabh Kulhare , Courosh Mehanian , Charles B Delahunt , Daniel E Shea , Zohreh Laverriere , Ishan Shah , Matthew P Horning

Diffusion models have recently achieved astonishing performance in generating high-fidelity photo-realistic images. Given their huge success, it is still unclear whether synthetic images are applicable for knowledge distillation when real…

Computer Vision and Pattern Recognition · Computer Science 2023-05-23 Zheng Li , Yuxuan Li , Penghai Zhao , Renjie Song , Xiang Li , Jian Yang

Incorporating diffusion-generated synthetic data into adversarial training (AT) has been shown to substantially improve the training of robust image classifiers. In this work, we extend the role of diffusion models beyond merely generating…

Machine Learning · Computer Science 2026-02-24 Pin-Han Huang , Shang-Tse Chen , Hsuan-Tien Lin

Modern learning-based approaches to 3D-aware image synthesis achieve high photorealism and 3D-consistent viewpoint changes for the generated images. Existing approaches represent instances in a shared canonical space. However, for…

Computer Vision and Pattern Recognition · Computer Science 2024-04-15 Katja Schwarz , Seung Wook Kim , Jun Gao , Sanja Fidler , Andreas Geiger , Karsten Kreis

Diffusion models achieve state-of-the-art image generation but remain computationally costly due to iterative denoising. Latent-space models like Stable Diffusion reduce overhead yet lose fine detail, while retrieval-augmented methods…

Machine Learning · Computer Science 2025-12-23 Bilal Faye , Hanane Azzag , Mustapha Lebbah

Synthetic data generation is an important application of machine learning in the field of medical imaging. While existing approaches have successfully applied fine-tuned diffusion models for synthesizing medical images, we explore potential…

Computer Vision and Pattern Recognition · Computer Science 2024-10-04 Lakshmi Nair

Medical imaging plays a vital role in modern diagnostics and treatment. The temporal nature of disease or treatment progression often results in longitudinal data. Due to the cost and potential harm, acquiring large medical datasets…

Computer Vision and Pattern Recognition · Computer Science 2023-01-16 Julian Schön , Raghavendra Selvan , Lotte Nygård , Ivan Richter Vogelius , Jens Petersen

Diffusion models are central to modern generative modeling, and understanding how they balance memorization and generalization is critical for reliable deployment. Recent work has shown that memorization in diffusion models is shaped by…

Machine Learning · Computer Science 2026-04-28 Bingqing Jiang , Difan Zou

Generative models have demonstrated strong performance in conditional settings and can be viewed as a form of data compression, where the condition serves as a compact representation. However, their limited controllability and…

Machine Learning · Computer Science 2025-07-04 Xiao Li , Liangji Zhu , Anand Rangarajan , Sanjay Ranka

Recent advancements in text-to-image diffusion models have demonstrated their remarkable capability to generate high-quality images from textual prompts. However, increasing research indicates that these models memorize and replicate images…

Computer Vision and Pattern Recognition · Computer Science 2025-07-01 Jie Ren , Yaxin Li , Shenglai Zeng , Han Xu , Lingjuan Lyu , Yue Xing , Jiliang Tang

Magnetic resonance (MR) imaging, including cardiac MR, is prone to domain shift due to variations in imaging devices and acquisition protocols. This challenge limits the deployment of trained AI models in real-world scenarios, where…

Computer Vision and Pattern Recognition · Computer Science 2025-08-11 Xin Ci Wong , Duygu Sarikaya , Kieran Zucker , Marc De Kamps , Nishant Ravikumar

Medical image processing has been highlighted as an area where deep learning-based models have the greatest potential. However, in the medical field in particular, problems of data availability and privacy are hampering research progress…

Image and Video Processing · Electrical Eng. & Systems 2023-10-27 Christoph Angermann , Johannes Bereiter-Payr , Kerstin Stock , Markus Haltmeier , Gerald Degenhart

Generative modelling and synthetic data can be a surrogate for real medical imaging datasets, whose scarcity and difficulty to share can be a nuisance when delivering accurate deep learning models for healthcare applications. In recent…

Image and Video Processing · Electrical Eng. & Systems 2024-02-27 Virginia Fernandez , Walter Hugo Lopez Pinaya , Pedro Borges , Mark S. Graham , Tom Vercauteren , M. Jorge Cardoso

Diffusion models (DMs) are one of the most widely used generative models for producing high quality images. However, a flurry of recent papers points out that DMs are least private forms of image generators, by extracting a significant…

Machine Learning · Statistics 2025-03-06 Michael F. Liu , Saiyue Lyu , Margarita Vinaroz , Mijung Park

Diffusion models, a family of generative models based on deep learning, have become increasingly prominent in cutting-edge machine learning research. With a distinguished performance in generating samples that resemble the observed data,…

Machine Learning · Computer Science 2023-05-02 Lequan Lin , Zhengkun Li , Ruikun Li , Xuliang Li , Junbin Gao

Many approaches have been proposed to use diffusion models to augment training datasets for downstream tasks, such as classification. However, diffusion models are themselves trained on large datasets, often with noisy annotations, and it…

Computer Vision and Pattern Recognition · Computer Science 2023-12-01 Max F. Burg , Florian Wenzel , Dominik Zietlow , Max Horn , Osama Makansi , Francesco Locatello , Chris Russell