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Can ChatGPT diagnose Alzheimer's Disease (AD)? AD is a devastating neurodegenerative condition that affects approximately 1 in 9 individuals aged 65 and older, profoundly impairing memory and cognitive function. This paper utilises 9300…

Machine Learning · Computer Science 2025-02-12 Quoc-Toan Nguyen , Linh Le , Xuan-The Tran , Thomas Do , Chin-Teng Lin

This study is based on the Alzheimer's Disease Neuroimaging Initiative (ADNI) dataset and aims to explore early detection and disease progression in Alzheimer's disease (AD). We employ innovative data preprocessing strategies, including the…

Machine Learning · Computer Science 2024-02-14 Mingyang Li , Hongyu Liu , Yixuan Li , Zejun Wang , Yuan Yuan , Honglin Dai

Alzheimer's disease (AD) is a progressive and irreversible neurodegenerative disease. Early and precise diagnosis of AD is crucial for timely intervention and treatment planning to alleviate the progressive neurodegeneration. However, most…

Image and Video Processing · Electrical Eng. & Systems 2025-07-29 Wenlong Hou , Guangqian Yang , Ye Du , Yeung Lau , Lihao Liu , Junjun He , Ling Long , Shujun Wang

Early diagnosis, playing an important role in preventing progress and treating the Alzheimer's disease (AD), is based on classification of features extracted from brain images. The features have to accurately capture main AD-related…

Machine Learning · Computer Science 2016-07-05 Ehsan Hosseini-Asl , Georgy Gimel'farb , Ayman El-Baz

Reliable detection of the prodromal stages of Alzheimer's disease (AD) remains difficult even today because, unlike other neurocognitive impairments, there is no definitive diagnosis of AD in vivo. In this context, existing research has…

Machine Learning · Computer Science 2021-08-03 Amish Mittal , Sourav Sahoo , Arnhav Datar , Juned Kadiwala , Hrithwik Shalu , Jimson Mathew

Neurodegeneration as measured through magnetic resonance imaging (MRI) is recognized as a potential biomarker for diagnosing Alzheimer's disease (AD), but is generally considered less specific than amyloid or tau based biomarkers. Due to a…

Computer Vision and Pattern Recognition · Computer Science 2024-08-06 Rosemary He , Gabriella Ang , Daniel Tward

Dementia is a growing problem as our society ages, and detection methods are often invasive and expensive. Recent deep-learning techniques can offer a faster diagnosis and have shown promising results. However, they require large amounts of…

Computation and Language · Computer Science 2022-07-19 Anna Hlédiková , Dominika Woszczyk , Alican Akman , Soteris Demetriou , Björn Schuller

Alzheimers disease is a deadly neurological condition, impairing important memory and brain functions. Alzheimers disease promotes brain shrinkage, ultimately leading to dementia. Dementia diagnosis typically takes 2.8 to 4.4 years after…

Deep learning methods based on Convolutional Neural Networks (CNNs) have shown great potential to improve early and accurate diagnosis of Alzheimer's disease (AD) dementia based on imaging data. However, these methods have yet to be widely…

Computer Vision and Pattern Recognition · Computer Science 2025-01-22 Wenjie Kang , Lize Jiskoot , Peter De Deyn , Geert Biessels , Huiberdina Koek , Jurgen Claassen , Huub Middelkoop , Wiesje Flier , Willemijn J. Jansen , Stefan Klein , Esther Bron

Diagnosing Alzheimer's disease (AD) involves a deliberate diagnostic process owing to its innate traits of irreversibility with subtle and gradual progression. These characteristics make AD biomarker identification from structural brain…

Machine Learning · Computer Science 2022-07-28 Ahmad Wisnu Mulyadi , Wonsik Jung , Kwanseok Oh , Jee Seok Yoon , Heung-Il Suk

The uncertainty of clinical examinations frequently leads to irregular observation intervals in longitudinal imaging data, posing challenges for modeling disease progression.Most existing imaging-based disease prediction models operate in…

Computer Vision and Pattern Recognition · Computer Science 2025-11-26 Xin Hong , Ying Shi , Yinhao Li , Yen-Wei Chen

Alzheimer's disease (AD) is a complex neurodegenerative disorder that affects millions of people worldwide. Due to the heterogeneous nature of AD, its diagnosis and treatment pose critical challenges. Consequently, there is a growing…

Machine Learning · Computer Science 2024-10-08 Tianyi Wei , Shu Yang , Davoud Ataee Tarzanagh , Jingxuan Bao , Jia Xu , Patryk Orzechowski , Joost B. Wagenaar , Qi Long , Li Shen

Alzheimer's disease is a human brain disease that affects a significant fraction of the population by causing problems with short-term memory, thinking, spatial orientation and behavior, memory loss and other intellectual abilities. Up to…

Neurons and Cognition · Quantitative Biology 2012-10-02 Athanasios Alexiou , Panayiotis Vlamos

Alzheimer's disease (AD) is the main cause of dementia which is accompanied by loss of memory and may lead to severe consequences in peoples' everyday life if not diagnosed on time. Very few works have exploited transformer-based networks…

Computation and Language · Computer Science 2022-08-15 Loukas Ilias , Dimitris Askounis

Alzheimer's disease (AD) is a complex neurodegenerative disorder characterized by the progressive accumulation of misfolded proteins, leading to cognitive decline. This study presents a novel stochastic modelling approach to simulate the…

Neurons and Cognition · Quantitative Biology 2024-11-06 Alec MacIver , Hina Shaheen

Alzheimer's Disease (AD) is an irreversible neurodegenerative disease affecting 50 million people worldwide. Low-cost, accurate identification of key markers of AD is crucial for timely diagnosis and intervention. Language impairment is one…

Computation and Language · Computer Science 2025-05-27 Tingyu Mo , Jacqueline C. K. Lam , Victor O. K. Li , Lawrence Y. L. Cheung

Alzheimer's disease (AD) is a neuro-degenerative disease that can cause dementia and result severe reduction in brain function inhibiting simple tasks especially if no preventative care is taken. Over 1 in 9 Americans suffer from AD induced…

Image and Video Processing · Electrical Eng. & Systems 2023-06-21 Paul K. Mandal , Rakesh Mahto

The automatic early diagnosis of prodromal stages of Alzheimer's disease is of great relevance for patient treatment to improve quality of life. We address this problem as a multi-modal classification task. Multi-modal data provides richer…

Healthcare datasets present many challenges to both machine learning and statistics as their data are typically heterogeneous, censored, high-dimensional and have missing information. Feature selection is often used to identify the…

Machine Learning · Computer Science 2022-07-06 Annette Spooner , Gelareh Mohammadi , Perminder S. Sachdev , Henry Brodaty , Arcot Sowmya

Exploring the application of deep learning technologies in the field of medical diagnostics, Magnetic Resonance Imaging (MRI) provides a unique perspective for observing and diagnosing complex neurodegenerative diseases such as Alzheimer…

Image and Video Processing · Electrical Eng. & Systems 2024-03-26 Shaojie Li , Haichen Qu , Xinqi Dong , Bo Dang , Hengyi Zang , Yulu Gong
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