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Alzheimer's disease (AD) and sleep disorders exhibit a close association, where disruptions in sleep patterns often precede the onset of Mild Cognitive Impairment (MCI) and early-stage AD. This study delves into the potential of utilizing…

Speech-based automatic detection of Alzheimer's disease (AD) and depression has attracted increased attention. Confidence estimation is crucial for a trust-worthy automatic diagnostic system which informs the clinician about the confidence…

Computation and Language · Computer Science 2024-09-10 Wen Wu , Chao Zhang , Philip C. Woodland

Alzheimer's disease (AD) is a progressive neurodegenerative disorder and a major cause of dementia. Structural MRI is widely used to analyze AD-related brain atrophy; however, most deep learning methods rely on computationally expensive 3D…

Computer Vision and Pattern Recognition · Computer Science 2026-04-28 Towhidul Islam , Mufti Mahmud

Introduction- This paper mainly describes a way to detect with high accuracy patients with early-stage Alzheimer's disease (ES-AD) versus healthy control (HC) subjects, from datasets built with handwriting and drawing task records. Method-…

Machine Learning · Computer Science 2021-03-19 Alain Petrowski

Alzheimer's disease (AD) emerges from a complex interplay of molecular, cellular, and network-level disturbances that are not easily captured by traditional reductionist frameworks. Conventional analyses of gene expression often rely on…

Quantitative Methods · Quantitative Biology 2025-12-11 Aya Samadzelkava

Over the past decade, machine learning techniques especially predictive modeling and pattern recognition in biomedical sciences from drug delivery system to medical imaging has become one of the important methods which are assisting…

Computer Vision and Pattern Recognition · Computer Science 2016-03-30 Saman Sarraf , Ghassem Tofighi

Retinal optical coherence tomography (OCT) images are the biomarkers for neurodegenerative diseases, which are rising in prevalence. Early detection of Alzheimer's disease using retinal OCT is a primary challenging task. This work utilizes…

Image and Video Processing · Electrical Eng. & Systems 2025-08-19 Siva Manohar Reddy Kesu , Neelam Sinha , Hariharan Ramasangu , Thomas Gregor Issac

Early diagnosis of Alzheimer's disease (AD) is crucial in facilitating preventive care and delay progression. Speech based automatic AD screening systems provide a non-intrusive and more scalable alternative to other clinical screening…

Machine Learning · Computer Science 2022-08-09 Yi Wang , Tianzi Wang , Zi Ye , Lingwei Meng , Shoukang Hu , Xixin Wu , Xunying Liu , Helen Meng

The accurate diagnosis of Alzheimer's disease (AD) and prognosis of mild cognitive impairment (MCI) conversion are crucial for early intervention. However, existing multimodal methods face several challenges, from the heterogeneity of input…

Machine Learning · Computer Science 2025-03-20 Chenyu Liu , Luca Rossi

Anomaly detection (AD) has been extensively studied and applied in a wide range of scenarios in the recent past. However, there are still gaps between achieved and desirable levels of recognition accuracy for making AD for practical…

Computer Vision and Pattern Recognition · Computer Science 2024-06-10 Peng Xing , Dong Zhang , Jinhui Tang , Zechao li

Advances in deep learning (DL)-based models for brain image analysis have significantly enhanced the accuracy of Alzheimer's disease (AD) diagnosis, allowing for more timely interventions. Despite these advancements, most current DL models…

Image and Video Processing · Electrical Eng. & Systems 2024-10-18 Yooseung Shin , Kwanseok Oh , Heung-Il Suk

Alzheimer's disease is a progressive form of dementia that results in problems with memory, thinking, and behavior. It often starts with abnormal aggregation and deposition of beta amyloid and tau, followed by neuronal damage such as…

Applications · Statistics 2022-06-03 Dengdeng Yu , Linbo Wang , Dehan Kong , Hongtu Zhu

Alzheimer's disease and Frontotemporal dementia are two major types of dementia. Their accurate diagnosis and differentiation is crucial for determining specific intervention and treatment. However, differential diagnosis of these two types…

Image and Video Processing · Electrical Eng. & Systems 2022-06-16 Huy-Dung Nguyen , Michaël Clément , Boris Mansencal , Pierrick Coupé

Alzheimer's disease (AD) stands as the predominant cause of dementia, characterized by a gradual decline in speech and language capabilities. Recent deep-learning advancements have facilitated automated AD detection through spontaneous…

Computation and Language · Computer Science 2024-09-20 Chin-Po Chen , Jeng-Lin Li

Alzheimer's disease (AD) is a progressive neurodegenerative disorder that severely impairs survival and quality of life. While anti-amyloid beta (Abeta) therapies can slow disease progression, their efficacy depends on personalized dosing…

Optimization and Control · Mathematics 2025-11-10 Sun Lee , Chiu-Yen Kao , Zhiyuan Li , Tingting Dan , Guorong Wu , Wenrui Hao

Objective Alzheimer disease (AD) is the most common cause of dementia, a syndrome characterized by cognitive impairment severe enough to interfere with activities of daily life. We aimed to conduct a systematic literature review (SLR) of…

Quantitative Methods · Quantitative Biology 2021-08-31 Sayantan Kumar , Inez Oh , Suzanne Schindler , Albert M Lai , Philip R O Payne , Aditi Gupta

Alzheimer's disease is a debilitating disorder marked by a decline in cognitive function. Timely identification of the disease is essential for the development of personalized treatment strategies that aim to mitigate its progression. The…

Computer Vision and Pattern Recognition · Computer Science 2025-11-27 Xin Hong , Kaifeng Huang

Alzheimer's disease is a common cognitive disorder in the elderly. Early and accurate diagnosis of Alzheimer's disease (AD) has a major impact on the progress of research on dementia. At present, researchers have used machine learning…

Sound · Computer Science 2024-02-20 Xiaohui Zhang , Wenjie Fu , Mangui Liang

The evolution of deep learning and artificial intelligence has significantly reshaped technological landscapes. However, their effective application in crucial sectors such as medicine demands more than just superior performance, but…

Computer Vision and Pattern Recognition · Computer Science 2024-02-27 Yasmine Mustafa , Tie Luo

Alzheimer's disease is the most common dementia leading to an irreversible neurodegenerative process. To date, subject revealed advanced brain structural alterations when the diagnosis is established. Therefore, an earlier diagnosis of this…

Computer Vision and Pattern Recognition · Computer Science 2018-07-10 Kilian Hett , Vinh-Thong Ta , Jose Vicente Manjon , Pierrick Coupé
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