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Over the past years, the ever-growing trend on data storage demand, more specifically for "cold" data (rarely accessed data), has motivated research for alternative systems of data storage. Because of its biochemical characteristics,…

Machine Learning · Computer Science 2022-03-21 Xavier Pic , Marc Antonini

Digital information can be encoded in the building-block sequence of macro-molecules, such as RNA and single-stranded DNA. Methods of "writing" and "reading" macromolecular strands are currently available, but they are slow and expensive.…

Emerging Technologies · Computer Science 2017-09-14 Masud Mansuripur , Pramod Khulbe

Motivated by applications in polymer-based data storage we introduced the new problem of characterizing the code rate and designing constant-weight binary $B_2$-sequences. Binary $B_2$-sequences are collections of binary strings of length…

Information Theory · Computer Science 2023-03-24 Jin Sima , Yun-Han Li , Ilan Shomorony , Olgica Milenkovic

Digital information can be encoded in the building-block sequence of macromolecules, such as RNA and single-stranded DNA. Methods of "writing" and "reading" macromolecular strands are currently available, but they are slow and expensive. In…

Emerging Technologies · Computer Science 2017-09-14 Pramod K. Khulbe , Raphael Gruener , Masud Mansuripur

In this paper, we describe a new type of DNA codes over two noncommutative rings $E$ and $F$ of order four with characteristic 2. Our DNA codes are based on quasi self-dual codes over $E$ and $F$. Using quasi self-duality, we can describe…

Information Theory · Computer Science 2021-05-17 Jon-Lark Kim , Dong Eun Ohk

Regenerating codes are a class of codes proposed for providing reliability of data and efficient repair of failed nodes in distributed storage systems. In this paper, we address the fundamental problem of handling errors and erasures during…

Information Theory · Computer Science 2015-03-20 K. V. Rashmi , Nihar B. Shah , Kannan Ramchandran , P. Vijay Kumar

Herein it is shown that in order to study the statistical properties of DNA sequences in bacterial chromosomes it suffices to consider only one half of the chromosome because they are similar to its corresponding complementary sequence in…

Genomics · Quantitative Biology 2009-11-10 Marco V. Jose , Tzipe Govezensky , Juan R. Bobadilla

Motivated by DNA storage in living organisms, and by known biological mutation processes, we study the reverse-complement string-duplication system. We fully classify the conditions under which the system has full expressiveness, for all…

Information Theory · Computer Science 2021-12-23 Eyar Ben-Tolila , Moshe Schwartz

Efficiently realizing logical operations on general stabilizer codes remains a long-standing challenge in fault tolerant quantum computing. While code surgery provides a general framework with provable guarantees by joint logical…

Quantum Physics · Physics 2026-05-22 Junyu Zhou , Ali Javadi-Abhari , Gushu Li

Phase-change memory (PCM) is a promising non-volatile solid-state memory technology. A PCM cell stores data by using its amorphous and crystalline states. The cell changes between these two states using high temperature. However, since the…

Information Theory · Computer Science 2012-07-20 Minghai Qin , Eitan Yaakobi , Paul H. Siegel

Designing short DNA words is a problem of constructing a set (i.e., code) of n DNA strings (i.e., words) with the minimum length such that the Hamming distance between each pair of words is at least k and the n words satisfy a set of…

Data Structures and Algorithms · Computer Science 2012-02-01 Ming-Yang Kao , Henry C. M. Leung , He Sun , Yong Zhang

We investigate the fundamental limits of the recently proposed random access coverage depth problem for DNA data storage. Under this paradigm, it is assumed that the user information consists of $k$ information strands, which are encoded…

Information Theory · Computer Science 2025-09-25 Anina Gruica , Daniella Bar-Lev , Alberto Ravagnani , Eitan Yaakobi

Constrained codes are used to prevent errors from occurring in various data storage and data transmission systems. They can help in increasing the storage density of magnetic storage devices, in managing the lifetime of electronic storage…

Information Theory · Computer Science 2022-09-07 Ahmed Hareedy , Beyza Dabak , Robert Calderbank

In this paper, we develop the theory for constructing DNA cyclic codes of odd length over $R=\Z_4[u]/\langle u^2-1 \rangle$ based on the deletion distance. Firstly, we relate DNA pairs with a special 16 elements of ring $R$. Cyclic codes of…

Information Theory · Computer Science 2016-03-15 Sukhamoy Pattanayak , Abhay Kumar Singh

The efficient storage of digital data is becoming very challenging over the years due to the exponential increase in the generation of data which can't compete with the existing storage resources. Furthermore, the infrequently accessed data…

Emerging Technologies · Computer Science 2021-03-18 Melpomeni Dimopoulou , Eva Gil San Antonio , Marc Antonini

DNA-synthesis providers screen incoming orders by searching the requested sequence against curated hazard lists. We show that this baseline collapses to a 100% false-flag rate when the hazardous sequence comes from a taxonomic family absent…

Genomics · Quantitative Biology 2026-05-04 Najmul Hasan

In this paper, we quantify how much codes can reduce the data retrieval latency in storage systems. By combining a simple linear code with a novel request scheduling algorithm, which we call Blocking-one Scheduling (BoS), we show…

Optimization and Control · Mathematics 2012-02-08 Longbo Huang , Sameer Pawar , Hao Zhang , Kannan Ramchandran

Maximum distance separable (MDS) codes have the optimal trade-off between storage efficiency and fault tolerance, which are widely used in distributed storage systems. As typical non-MDS codes, simple regenerating codes (SRCs) can achieve…

Information Theory · Computer Science 2023-09-06 Zhengyi Jiang , Hao Shi , Zhongyi Huang , Bo Bai , Gong Zhang , Hanxu Hou

Sequencing a DNA strand, as part of the read process in DNA storage, produces multiple noisy copies which can be combined to produce better estimates of the original strand; this is called trace reconstruction. One can reduce the error rate…

Information Theory · Computer Science 2024-08-22 Sundara Rajan Srinivasavaradhan , Sivakanth Gopi , Henry D. Pfister , Sergey Yekhanin

Regenerating codes allow distributed storage systems to recover from the loss of a storage node while transmitting the minimum possible amount of data across the network. We present a systematic computer search for optimal systematic…

Information Theory · Computer Science 2009-10-14 Daniel Cullina , Alexandros G. Dimakis , Tracey Ho
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