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To make informative public policy decisions in battling the ongoing COVID-19 pandemic, it is important to know the disease prevalence in a population. There are two intertwined difficulties in estimating this prevalence based on testing…

Methodology · Statistics 2020-12-01 Bryan Cai , John P. A. Ioannidis , Eran Bendavid , Lu Tian

We propose a mathematical model based on probability theory to optimize COVID-19 testing by a multi-step batch testing approach with variable batch sizes. This model and simulation tool dramatically increase the efficiency and efficacy of…

Methodology · Statistics 2021-01-11 Hongshik Ahn , Haoran Jiang , Xiaolin Li

The outbreak of the novel coronavirus (COVID-19) is unfolding as a major international crisis whose influence extends to every aspect of our daily lives. Effective testing allows infected individuals to be quarantined, thus reducing the…

Machine Learning · Computer Science 2020-07-28 Rahul Singh , Fang Liu , Ness B. Shroff

Matched case-control studies are commonly employed in epidemiological research for their convenience and efficiency. Analysis of secondary outcomes can yield valuable insights into biological pathways and help identify genetic variants of…

Methodology · Statistics 2026-02-24 Shanshan Liu , Guoqing Diao

We study a statistical procedure based on higher criticism (HC) to address the sparse multi-stream quickest change-point detection problem. Namely, we aim to detect a potential change in the distribution of multiple data streams at some…

Methodology · Statistics 2025-04-22 Tingnan Gong , Alon Kipnis , Yao Xie

We present the Small-Coupling Dynamic Cavity (SCDC) method, a novel generalized mean-field approximation for epidemic inference and risk assessment within a fully Bayesian framework. SCDC accounts for non-causal effects of observations and…

Disordered Systems and Neural Networks · Physics 2025-05-01 Alfredo Braunstein , Giovanni Catania , Luca Dall'Asta , Matteo Mariani , Fabio Mazza , Mattia Tarabolo

While non-invasive sampling is more and more commonly used in capture-recapture (CR) experiments, it carries a higher risk of misidentifications than direct observations. As a consequence, one must screen the data to retain only the…

Quantitative Methods · Quantitative Biology 2023-04-04 Rémi Fraysse , Rémi Choquet , Carlo Costantini , Roger Pradel

We consider a network where an infection cascade has taken place and a subset of infected nodes has been partially observed. Our goal is to reconstruct the underlying cascade that is likely to have generated these observations. We reduce…

Social and Information Networks · Computer Science 2018-11-21 Han Xiao , Cigdem Aslay , Aristides Gionis

Early outbreak detection is a key aspect in the containment of infectious diseases, as it enables the identification and isolation of infected individuals before the disease can spread to a larger population. Instead of detecting unexpected…

Machine Learning · Computer Science 2021-10-19 Michael Rapp , Moritz Kulessa , Eneldo Loza Mencía , Johannes Fürnkranz

We argue that frequent sampling of the fraction of infected people (either by random testing or by analysis of sewage water), is central to managing the COVID-19 pandemic because it both measures in real time the key variable controlled by…

Populations and Evolution · Quantitative Biology 2020-07-24 Markus Müller , Peter M. Derlet , Christopher Mudry , Gabriel Aeppli

Detecting occupied subbands is a key task for wireless applications such as unlicensed spectrum access. Recently, detection methods were proposed that extract per-subband features from sub-Nyquist baseband samples and then apply…

Signal Processing · Electrical Eng. & Systems 2024-05-28 Hyojin Lee , Sangwoo Park , Osvaldo Simeone , Yonina C. Eldar , Joonhyuk Kang

Count-valued autoregressions are widely used to analyse time-series of reported infectious-disease cases because of their close connection with discrete-time transmission models. However, when such models are applied directly to…

Applications · Statistics 2025-09-16 Justin J. Slater , Sindi Bebeziqi

Conformal risk control (CRC) is a recently proposed technique that applies post-hoc to a conventional point predictor to provide calibration guarantees. Generalizing conformal prediction (CP), with CRC, calibration is ensured for a set…

Machine Learning · Computer Science 2024-05-02 Kfir M. Cohen , Sangwoo Park , Osvaldo Simeone , Shlomo Shamai

We intend to create a new risk assessment methodology that combines the best characteristics of both risk score and machine learning models. More specifically, we aim to develop a method that, besides having a good performance, offers a…

Machine Learning · Computer Science 2021-10-19 Francisco Valente , Jorge Henriques , Simão Paredes , Teresa Rocha , Paulo de Carvalho , João Morais

Given the urgent informational needs connected with the diffusion of infection with regard to the COVID-19 pandemic, in this paper, we propose a sampling design for building a continuous-time surveillance system. Compared with other…

We investigate adaptive strategies to robustly and optimally control the COVID-19 pandemic via social distancing measures based on the example of Germany. Our goal is to minimize the number of fatalities over the course of two years without…

Populations and Evolution · Quantitative Biology 2021-02-09 Johannes Köhler , Lukas Schwenkel , Anne Koch , Julian Berberich , Patricia Pauli , Frank Allgöwer

The case-cohort design is a commonly used cost-effective sampling strategy for large cohort studies, where some covariates are expensive to measure or obtain. In this paper, we consider regression analysis under a case-cohort study with…

Methodology · Statistics 2023-10-24 Qingning Zhou , Kin Yau Wong

Relative abundance, measured as the number of animals caught per unit of sampling effort (CPUE), is commonly used to monitor fish and wildlife populations, largely because sampling methods are cost-effective to implement. Modeling relative…

Applications · Statistics 2026-05-12 Kevin M. Collins , Erin M. Schliep , Tyler Wagner , Christopher K. Wikle

Regression test case prioritization (RTCP) aims to improve the rate of fault detection by executing more important test cases as early as possible. Various RTCP techniques have been proposed based on different coverage criteria. Among them,…

Software Engineering · Computer Science 2020-07-02 Rubing Huang , Quanjun Zhang , Dave Towey , Weifeng Sun , Jinfu Chen

In the post-pandemic era of COVID-19, hospitalization remains a primary public health concern and wastewater surveillance has become an important tool for monitoring its dynamics at the level of community. However, there is usually no…

Methodology · Statistics 2026-01-14 K. Ken Peng , Charmaine B. Dean , Robert Delatolla , X. Joan Hu , Elizabeth Renouf