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We propose a monitoring strategy for efficient and robust estimation of disease prevalence and case numbers within closed and enumerated populations such as schools, workplaces, or retirement communities. The proposed design relies largely…

Methodology · Statistics 2024-04-22 Robert H. Lyles , Yuzi Zhang , Lin Ge , Lance A. Waller

We extend recently proposed design-based capture-recapture (CRC) methods for prevalence estimation among registry participants, in order to enhance treatment effect evaluation among a trial-eligible target population. The so-called ``anchor…

Methodology · Statistics 2025-10-28 Lin Ge , Yuzi Zhang , Lance A. Waller , Robert H. Lyles

Surveillance research is of great importance for effective and efficient epidemiological monitoring of case counts and disease prevalence. Taking specific motivation from ongoing efforts to identify recurrent cases based on the Georgia…

Methodology · Statistics 2023-07-04 Lin Ge , Yuzi Zhang , Kevin C. Ward , Timothy L. Lash , Lance A. Waller , Robert H. Lyles

In this paper, we expand upon and refine a monitoring strategy proposed for surveillance of diseases in finite, closed populations. This monitoring strategy consists of augmenting an arbitrarily non-representative data stream (such as a…

In epidemiological studies, the capture-recapture (CRC) method is a powerful tool that can be used to estimate the number of diseased cases or potentially disease prevalence based on data from overlapping surveillance systems. Estimators…

Applications · Statistics 2023-06-21 Yuzi Zhang , Lin Ge , Lance A. Waller , Robert H. Lyles

Capture-recapture (CRC) surveys are used to estimate the size of a population whose members cannot be enumerated directly. CRC surveys have been used to estimate the number of Covid-19 infections, people who use drugs, sex workers, conflict…

Methodology · Statistics 2022-10-17 Jinghao Sun , Luk Van Baelen , Els Plettinckx , Forrest W. Crawford

As the COVID-19 pandemic puts pressure on healthcare systems worldwide, the computed tomography image based AI diagnostic system has become a sustainable solution for early diagnosis. However, the model-wise vulnerability under adversarial…

Image and Video Processing · Electrical Eng. & Systems 2022-12-01 Kun Xiang , Xing Zhang , Jinwen She , Jinpeng Liu , Haohan Wang , Shiqi Deng , Shancheng Jiang

Formulating accurate and robust classification strategies is a key challenge of developing diagnostic and antibody tests. Methods that do not explicitly account for disease prevalence and uncertainty therein can lead to significant…

Methodology · Statistics 2022-02-01 Paul N. Patrone , Anthony J. Kearsley

The pandemic linked to COVID-19 infection represents an unprecedented clinical and healthcare challenge for many medical researchers attempting to prevent its worldwide spread. This pandemic also represents a major challenge for…

The spread of COVID-19 makes it essential to investigate its prevalence. In such investigation research, as far as we know, the widely-used sampling methods didn't use the information sufficiently about the numbers of the previously…

Applications · Statistics 2022-01-04 Ze Liu , Siyu Yi , Jianghu , Dong , Min-Qian Liu , Yongdao Zhou

Epidemiologic screening programs often make use of tests with small, but non-zero probabilities of misdiagnosis. In this article, we assume the target population is finite with a fixed number of true cases, and that we apply an imperfect…

Methodology · Statistics 2024-04-22 Lin Ge , Yuzi Zhang , Lance A. Waller , Robert H. Lyles

The interpretation of sampling data plays a crucial role in policy response to the spread of a disease during an epidemic, such as the COVID-19 epidemic of 2020. However, this is a non-trivial endeavor due to the complexity of real world…

Populations and Evolution · Quantitative Biology 2020-07-30 James D. Brunner , Nicholas Chia

Unsupervised anomaly detection is a promising technique for identifying unusual patterns in data without the need for labeled training examples. This approach is particularly valuable for early case detection in epidemic management,…

Machine Learning · Computer Science 2025-05-06 Ghazal Ghajari , Mithun Kumar PK , Fathi Amsaad

Early detection of patients vulnerable to infections acquired in the hospital environment is a challenge in current health systems given the impact that such infections have on patient mortality and healthcare costs. This work is focused on…

Incidence vs Cumulative Cases (ICC) curves are introduced and shown to provide a simple framework for parameter identification in the case of the most elementary epidemiological model, consisting of susceptible, infected, and removed…

Populations and Evolution · Quantitative Biology 2021-04-14 Joceline Lega

With the ongoing COVID-19 pandemic, understanding the characteristics of the virus has become an important and challenging task in the scientific community. While tests do exist for COVID-19, the goal of our research is to explore other…

Computer Vision and Pattern Recognition · Computer Science 2021-12-02 Jacob Householder , Andrew Householder , John Paul Gomez-Reed , Fredrick Park , Shuai Zhang

COVID-19, a viral respiratory pandemic, has rapidly spread throughout the globe. Large scale and rapid testing of the population is required to contain the disease, but such testing is prohibitive in terms of resources, cost and time.…

Populations and Evolution · Quantitative Biology 2020-07-21 Abhishek Srivastava , Anurag Mishra , Trusha Jayant Parekh , Sampreeti Jena

Continuous diagnosis and prognosis are essential for intensive care patients. It can provide more opportunities for timely treatment and rational resource allocation, especially for sepsis, a main cause of death in ICU, and COVID-19, a new…

Machine Learning · Computer Science 2022-10-07 Chenxi Sun , Hongyan Li , Moxian Song , Derun Cai , Baofeng Zhang , Shenda Hong

There is a constant need for many healthcare programs to timely address problems with infection prevention and control (IP&C). For example, pathogens can be transmitted among patients with cystic fibrosis (CF) in both the inpatient and…

Methodology · Statistics 2022-07-27 Xiaotong Jiang , William Stoudemire , Marianne S. Muhlebach , Michael R. Kosorok

Real-world classification domains, such as medicine, health and safety, and finance, often exhibit imbalanced class priors and have asynchronous misclassification costs. In such cases, the classification model must achieve a high recall…

Machine Learning · Computer Science 2021-05-11 Michał Koziarski , Colin Bellinger , Michał Woźniak
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