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Linking biomedical entities is an essential aspect in biomedical natural language processing tasks, such as text mining and question answering. However, a difficulty of linking the biomedical entities using current large language models…

Computation and Language · Computer Science 2023-08-29 Xi Yan , Cedric Möller , Ricardo Usbeck

Despite their strong linguistic capabilities, Large Language Models (LLMs) are computationally demanding and require substantial resources for fine-tuning, which is unadapted to privacy and budget constraints of many healthcare settings. To…

Computation and Language · Computer Science 2026-04-30 Pierre Epron , Adrien Coulet , Mehwish Alam

While model architecture and training objectives are well-studied, tokenization, particularly in multilingual contexts, remains a relatively neglected aspect of Large Language Model (LLM) development. Existing tokenizers often exhibit high…

Contextualized word embeddings derived from pre-trained language models (LMs) show significant improvements on downstream NLP tasks. Pre-training on domain-specific corpora, such as biomedical articles, further improves their performance.…

Computation and Language · Computer Science 2019-04-05 Qiao Jin , Bhuwan Dhingra , William W. Cohen , Xinghua Lu

Recently, Large Language Models (LLM) have demonstrated impressive capability to solve a wide range of tasks. However, despite their success across various tasks, no prior work has investigated their capability in the biomedical domain yet.…

Computation and Language · Computer Science 2024-02-21 Israt Jahan , Md Tahmid Rahman Laskar , Chun Peng , Jimmy Huang

Large language models (LLMs) have demonstrated dominating performance in many NLP tasks, especially on generative tasks. However, they often fall short in some information extraction tasks, particularly those requiring domain-specific…

Computation and Language · Computer Science 2023-09-22 Junyi Bian , Jiaxuan Zheng , Yuyi Zhang , Shanfeng Zhu

Neural language models typically tokenise input text into sub-word units to achieve an open vocabulary. The standard approach is to use a single canonical tokenisation at both train and test time. We suggest that this approach is…

Computation and Language · Computer Science 2021-09-22 Kris Cao , Laura Rimell

The best performing transformer-based language models use subword tokenization techniques, such as Byte-Pair-Encoding (BPE). However, these approaches often overlook linguistic principles, such as morphological segmentation, which we…

Computation and Language · Computer Science 2025-04-03 Mikkel Wildner Kildeberg , Emil Allerslev Schledermann , Nicolaj Larsen , Rob van der Goot

With the growing amount of text in health data, there have been rapid advances in large pre-trained models that can be applied to a wide variety of biomedical tasks with minimal task-specific modifications. Emphasizing the cost of these…

Biomedical question-answering (QA) has gained increased attention for its capability to provide users with high-quality information from a vast scientific literature. Although an increasing number of biomedical QA datasets has been recently…

Computation and Language · Computer Science 2021-02-17 Gabriele Pergola , Elena Kochkina , Lin Gui , Maria Liakata , Yulan He

In recent years, with the growing amount of biomedical documents, coupled with advancement in natural language processing algorithms, the research on biomedical named entity recognition (BioNER) has increased exponentially. However, BioNER…

Computation and Language · Computer Science 2020-09-22 Usman Naseem , Matloob Khushi , Vinay Reddy , Sakthivel Rajendran , Imran Razzak , Jinman Kim

The biomedical domain has sparked a significant interest in the field of Natural Language Processing (NLP), which has seen substantial advancements with pre-trained language models (PLMs). However, comparing these models has proven…

Pre-trained language models induce dense entity representations that offer strong performance on entity-centric NLP tasks, but such representations are not immediately interpretable. This can be a barrier to model uptake in important…

Computation and Language · Computer Science 2021-06-18 Diego Garcia-Olano , Yasumasa Onoe , Ioana Baldini , Joydeep Ghosh , Byron C. Wallace , Kush R. Varshney

Large language models (LLMs) have shown potential in biomedical applications, leading to efforts to fine-tune them on domain-specific data. However, the effectiveness of this approach remains unclear. This study evaluates the performance of…

The overwhelming amount of biomedical scientific texts calls for the development of effective language models able to tackle a wide range of biomedical natural language processing (NLP) tasks. The most recent dominant approaches are…

Computation and Language · Computer Science 2021-04-21 Giacomo Miolo , Giulio Mantoan , Carlotta Orsenigo

Large pretrained language models (PLMs) typically tokenize the input string into contiguous subwords before any pretraining or inference. However, previous studies have claimed that this form of subword tokenization is inadequate for…

Computation and Language · Computer Science 2022-04-12 Omri Keren , Tal Avinari , Reut Tsarfaty , Omer Levy

Background: Biomedical entity normalization is critical to biomedical research because the richness of free-text clinical data, such as progress notes, can often be fully leveraged only after translating words and phrases into structured…

Computation and Language · Computer Science 2024-05-27 Nicholas J Dobbins

Motivation: State-of-the-art biomedical named entity recognition (BioNER) systems often require handcrafted features specific to each entity type, such as genes, chemicals and diseases. Although recent studies explored using neural network…

Information Retrieval · Computer Science 2018-10-09 Xuan Wang , Yu Zhang , Xiang Ren , Yuhao Zhang , Marinka Zitnik , Jingbo Shang , Curtis Langlotz , Jiawei Han

Contextual embedding-based language models trained on large data sets, such as BERT and RoBERTa, provide strong performance across a wide range of tasks and are ubiquitous in modern NLP. It has been observed that fine-tuning these models on…

Computation and Language · Computer Science 2021-09-16 Vin Sachidananda , Jason S. Kessler , Yi-an Lai

Subword tokenization is an essential part of modern large language models (LLMs), yet its specific contributions to training efficiency and model performance remain poorly understood. In this work, we decouple the effects of subword…

Computation and Language · Computer Science 2026-05-15 Théo Gigant , Bowen Peng , Jeffrey Quesnelle