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Generative learning is a powerful tool for representation learning, and shows particular promise for problems in biomedical imaging. However, in this context, sampling from the distribution is secondary to finding representations of real…

Image and Video Processing · Electrical Eng. & Systems 2022-09-07 Simon Myles Thomas

Melanoma is one of the most aggressive forms of skin cancer, causing a large proportion of skin cancer deaths. However, melanoma diagnoses by pathologists shows low interrater reliability. As melanoma is a cancer of the melanocyte, there is…

Quantitative Methods · Quantitative Biology 2024-03-15 Mikio Tada , Ursula E. Lang , Iwei Yeh , Elizabeth S. Keiser , Maria L. Wei , Michael J. Keiser

Melanoma is the most lethal form of skin cancer, with an increasing incidence rate worldwide. Analyzing histological images of melanoma by localizing and classifying tissues and cell nuclei is considered the gold standard method for…

Computer Vision and Pattern Recognition · Computer Science 2025-09-03 Nima Torbati , Anastasia Meshcheryakova , Ramona Woitek , Sepideh Hatamikia , Diana Mechtcheriakova , Amirreza Mahbod

Nuclei instance segmentation on histopathology images is of great clinical value for disease analysis. Generally, fully-supervised algorithms for this task require pixel-wise manual annotations, which is especially time-consuming and…

Computer Vision and Pattern Recognition · Computer Science 2023-06-06 Yang Zhou , Yongjian Wu , Zihua Wang , Bingzheng Wei , Maode Lai , Jianzhong Shou , Yubo Fan , Yan Xu

Masked image modeling (MIM) has gained significant traction for its remarkable prowess in representation learning. As an alternative to the traditional approach, the reconstruction from corrupted images has recently emerged as a promising…

Computer Vision and Pattern Recognition · Computer Science 2024-07-17 Wenzhao Xiang , Chang Liu , Hang Su , Hongyang Yu

Recently, masked image modeling (MIM) has offered a new methodology of self-supervised pre-training of vision transformers. A key idea of efficient implementation is to discard the masked image patches (or tokens) throughout the target…

Computer Vision and Pattern Recognition · Computer Science 2022-05-31 Xiaosong Zhang , Yunjie Tian , Wei Huang , Qixiang Ye , Qi Dai , Lingxi Xie , Qi Tian

Model pre-training is essential in human-centric perception. In this paper, we first introduce masked image modeling (MIM) as a pre-training approach for this task. Upon revisiting the MIM training strategy, we reveal that human structure…

Computer Vision and Pattern Recognition · Computer Science 2023-11-01 Junkun Yuan , Xinyu Zhang , Hao Zhou , Jian Wang , Zhongwei Qiu , Zhiyin Shao , Shaofeng Zhang , Sifan Long , Kun Kuang , Kun Yao , Junyu Han , Errui Ding , Lanfen Lin , Fei Wu , Jingdong Wang

Medical vision-and-language pre-training provides a feasible solution to extract effective vision-and-language representations from medical images and texts. However, few studies have been dedicated to this field to facilitate medical…

Computer Vision and Pattern Recognition · Computer Science 2022-09-16 Zhihong Chen , Yuhao Du , Jinpeng Hu , Yang Liu , Guanbin Li , Xiang Wan , Tsung-Hui Chang

Vision Transformers (ViTs) outperforms convolutional neural networks (CNNs) in several vision tasks with its global modeling capabilities. However, ViT lacks the inductive bias inherent to convolution making it require a large amount of…

Computer Vision and Pattern Recognition · Computer Science 2023-01-11 Jiawei Mao , Honggu Zhou , Xuesong Yin , Yuanqi Chang. Binling Nie. Rui Xu

Tissue phenotyping is a fundamental task in learning objective characterizations of histopathologic biomarkers within the tumor-immune microenvironment in cancer pathology. However, whole-slide imaging (WSI) is a complex computer vision in…

Computer Vision and Pattern Recognition · Computer Science 2022-03-02 Richard J. Chen , Rahul G. Krishnan

This work presents a novel method of exploring human brain-visual representations, with a view towards replicating these processes in machines. The core idea is to learn plausible computational and biological representations by correlating…

Computer Vision and Pattern Recognition · Computer Science 2020-04-21 Simone Palazzo , Concetto Spampinato , Isaak Kavasidis , Daniela Giordano , Joseph Schmidt , Mubarak Shah

Nuclei classification provides valuable information for histopathology image analysis. However, the large variations in the appearance of different nuclei types cause difficulties in identifying nuclei. Most neural network based methods are…

Computer Vision and Pattern Recognition · Computer Science 2023-02-23 Wei Lou , Xiang Wan , Guanbin Li , Xiaoying Lou , Chenghang Li , Feng Gao , Haofeng Li

Brain tumor image segmentation is a challenging research topic in which deep-learning models have presented the best results. However, the traditional way of training those models from many pre-annotated images leaves several unanswered…

Computer Vision and Pattern Recognition · Computer Science 2024-03-20 Matheus A. Cerqueira , Flávia Sprenger , Bernardo C. A. Teixeira , Alexandre X. Falcão

Masked image modeling is a promising self-supervised learning method for visual data. It is typically built upon image patches with random masks, which largely ignores the variation of information density between them. The question is: Is…

Computer Vision and Pattern Recognition · Computer Science 2024-01-09 Haijian Chen , Wendong Zhang , Yunbo Wang , Xiaokang Yang

Implicit Neural Representations (INRs) aim to parameterize discrete signals through implicit continuous functions. However, formulating each image with a separate neural network~(typically, a Multi-Layer Perceptron (MLP)) leads to…

Computer Vision and Pattern Recognition · Computer Science 2025-08-20 Wenyong Zhou , Taiqiang Wu , Zhengwu Liu , Yuxin Cheng , Chen Zhang , Ngai Wong

The automated analysis of medical images is currently limited by technical and biological noise and bias. The same source tissue can be represented by vastly different images if the image acquisition or processing protocols vary. For an…

Various multi-instance learning (MIL) based approaches have been developed and successfully applied to whole-slide pathological images (WSI). Existing MIL methods emphasize the importance of feature aggregators, but largely neglect the…

Computer Vision and Pattern Recognition · Computer Science 2025-05-13 Yicheng Song , Tiancheng Lin , Die Peng , Su Yang , Yi Xu

Recently, deep neural networks have greatly advanced histopathology image segmentation but usually require abundant annotated data. However, due to the gigapixel scale of whole slide images and pathologists' heavy daily workload, obtaining…

Computer Vision and Pattern Recognition · Computer Science 2023-03-13 Wentao Pan , Jiangpeng Yan , Hanbo Chen , Jiawei Yang , Zhe Xu , Xiu Li , Jianhua Yao

We present aMUSEd, an open-source, lightweight masked image model (MIM) for text-to-image generation based on MUSE. With 10 percent of MUSE's parameters, aMUSEd is focused on fast image generation. We believe MIM is under-explored compared…

Computer Vision and Pattern Recognition · Computer Science 2024-01-04 Suraj Patil , William Berman , Robin Rombach , Patrick von Platen

Masked Image Modeling (MIM) methods, like Masked Autoencoders (MAE), efficiently learn a rich representation of the input. However, for adapting to downstream tasks, they require a sufficient amount of labeled data since their rich features…

Computer Vision and Pattern Recognition · Computer Science 2023-09-15 Johannes Lehner , Benedikt Alkin , Andreas Fürst , Elisabeth Rumetshofer , Lukas Miklautz , Sepp Hochreiter