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Activity cliffs, which refer to pairs of molecules that are structurally similar but show significant differences in their potency, can lead to model representation collapse and make the model challenging to distinguish them. Our research…

Computer Vision and Pattern Recognition · Computer Science 2024-09-20 Zhixiang Cheng , Hongxin Xiang , Pengsen Ma , Li Zeng , Xin Jin , Xixi Yang , Jianxin Lin , Yang Deng , Bosheng Song , Xinxin Feng , Changhui Deng , Xiangxiang Zeng

Recent advancements in digital pathology have enabled comprehensive analysis of Whole-Slide Images (WSI) from tissue samples, leveraging high-resolution microscopy and computational capabilities. Despite this progress, there is a lack of…

Masked image modeling (MIM) has achieved promising results on various vision tasks. However, the limited discriminability of learned representation manifests there is still plenty to go for making a stronger vision learner. Towards this…

Computer Vision and Pattern Recognition · Computer Science 2024-01-30 Zhicheng Huang , Xiaojie Jin , Chengze Lu , Qibin Hou , Ming-Ming Cheng , Dongmei Fu , Xiaohui Shen , Jiashi Feng

Masked autoencoders (MAEs) have established themselves as a powerful method for unsupervised pre-training for computer vision tasks. While vanilla MAEs put equal emphasis on reconstructing the individual parts of the image, we propose to…

Computer Vision and Pattern Recognition · Computer Science 2024-02-26 Leon Sick , Dominik Engel , Pedro Hermosilla , Timo Ropinski

In this work, we explore regions as a potential visual analogue of words for self-supervised image representation learning. Inspired by Masked Autoencoding (MAE), a generative pre-training baseline, we propose masked region autoencoding to…

Computer Vision and Pattern Recognition · Computer Science 2024-01-08 Duy-Kien Nguyen , Vaibhav Aggarwal , Yanghao Li , Martin R. Oswald , Alexander Kirillov , Cees G. M. Snoek , Xinlei Chen

Neural fields excel in computer vision and robotics due to their ability to understand the 3D visual world such as inferring semantics, geometry, and dynamics. Given the capabilities of neural fields in densely representing a 3D scene from…

Computer Vision and Pattern Recognition · Computer Science 2024-07-19 Muhammad Zubair Irshad , Sergey Zakharov , Vitor Guizilini , Adrien Gaidon , Zsolt Kira , Rares Ambrus

Referring image segmentation is a typical multi-modal task, which aims at generating a binary mask for referent described in given language expressions. Prior arts adopt a bimodal solution, taking images and languages as two modalities…

Computer Vision and Pattern Recognition · Computer Science 2021-11-29 Zizhang Li , Mengmeng Wang , Jianbiao Mei , Yong Liu

This work contributes to breast cancer sub-type classification using histopathological images. We utilize masked autoencoders (MAEs) to learn a self-supervised embedding tailored for computer vision tasks in this domain. This embedding…

Computer Vision and Pattern Recognition · Computer Science 2025-06-10 Annalisa Chiocchetti , Marco Dossena , Christopher Irwin , Luigi Portinale

Featurizing microscopy images for use in biological research remains a significant challenge, especially for large-scale experiments spanning millions of images. This work explores the scaling properties of weakly supervised classifiers and…

Implicit neural representations (INRs) have emerged as a powerful paradigm for medical imaging via physics-informed unsupervised learning. Classical INRs optimize an entire network from scratch for each subject, leading to inefficient…

Computer Vision and Pattern Recognition · Computer Science 2026-05-07 Qing Wu , Xuanyu Tian , Chenhe Du , Haonan Zhang , Xiao Wang , Le Lu , Yuyao Zhang

Masked Autoencoders (MAEs) have been shown to be effective in pre-training Vision Transformers (ViTs) for natural and medical image analysis problems. By reconstructing missing pixel/voxel information in visible patches, a ViT encoder can…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Pengfei Gu , Huimin Li , Yejia Zhang , Chaoli Wang , Danny Z. Chen

We present an efficient approach for Masked Image Modeling (MIM) with hierarchical Vision Transformers (ViTs), allowing the hierarchical ViTs to discard masked patches and operate only on the visible ones. Our approach consists of three key…

Computer Vision and Pattern Recognition · Computer Science 2022-10-17 Lang Huang , Shan You , Mingkai Zheng , Fei Wang , Chen Qian , Toshihiko Yamasaki

Semantic segmentation of electron microscopy (EM) is an essential step to efficiently obtain reliable morphological statistics. Despite the great success achieved using deep convolutional neural networks (CNNs), they still produce coarse…

Computer Vision and Pattern Recognition · Computer Science 2021-01-11 Zhimin Yuan , Xiaofen Ma , Jiajin Yi , Zhengrong Luo , Jialin Peng

Masked Autoencoders (MAE) have shown great potentials in self-supervised pre-training for language and 2D image transformers. However, it still remains an open question on how to exploit masked autoencoding for learning 3D representations…

Computer Vision and Pattern Recognition · Computer Science 2022-10-17 Renrui Zhang , Ziyu Guo , Rongyao Fang , Bin Zhao , Dong Wang , Yu Qiao , Hongsheng Li , Peng Gao

AI-assisted nuclei segmentation in histopathological images is a crucial task in the diagnosis and treatment of cancer diseases. It decreases the time required to manually screen microscopic tissue images and can resolve the conflict…

Image and Video Processing · Electrical Eng. & Systems 2023-11-21 Hesham Ali , Idriss Tondji , Mennatullah Siam

Many real-world tasks such as classification of digital histopathology images and 3D object detection involve learning from a set of instances. In these cases, only a group of instances or a set, collectively, contains meaningful…

Machine Learning · Computer Science 2020-07-06 Shivam Kalra , Mohammed Adnan , Graham Taylor , Hamid Tizhoosh

Semi-supervised learning is of great significance in medical image segmentation by exploiting unlabeled data. Among its strategies, the co-training framework is prominent. However, previous co-training studies predominantly concentrate on…

Computer Vision and Pattern Recognition · Computer Science 2025-03-19 Pengcheng Zhou , Lantian Zhang , Wei Li

Multimodal MRI offers complementary information for brain tumor segmentation, but clinical scans often lack one or more modalities, which degrades segmentation performance. In this paper, we propose UniME (Uni-Encoder Meets Multi-Encoders),…

Computer Vision and Pattern Recognition · Computer Science 2026-04-27 Peibo Song , Xiaotian Xue , Jinshuo Zhang , Zihao Wang , Jinhua Liu , Shujun Fu , Fangxun Bao , Si Yong Yeo

Medical image segmentation typically adopts a point-wise convolutional segmentation head to predict dense labels, where each output channel is heuristically tied to a specific class. This rigid design limits both feature sharing and…

Computer Vision and Pattern Recognition · Computer Science 2025-11-20 Bin Xie , Gady Agam

Masked image modeling (MIM) methods typically operate in either raw pixel space (reconstructing masked patches) or latent feature space (aligning with a pre-trained teacher). We present MEDiC (Multi-objective Exploration of Distillation…

Computer Vision and Pattern Recognition · Computer Science 2026-04-01 Konstantinos Georgiou , Maofeng Tang , Hairong Qi
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