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Recently, Masked Image Modeling (MIM) achieves great success in self-supervised visual recognition. However, as a reconstruction-based framework, it is still an open question to understand how MIM works, since MIM appears very different…

Computer Vision and Pattern Recognition · Computer Science 2022-08-09 Xiangwen Kong , Xiangyu Zhang

For personalized medicines, very crucial intrinsic information is present in high dimensional omics data which is difficult to capture due to the large number of molecular features and small number of available samples. Different types of…

Machine Learning · Computer Science 2022-02-04 Sayed Hashim , Muhammad Ali , Karthik Nandakumar , Mohammad Yaqub

Automatic nuclei segmentation and classification play a vital role in digital pathology. However, previous works are mostly built on data with limited diversity and small sizes, making the results questionable or misleading in actual…

Image and Video Processing · Electrical Eng. & Systems 2023-05-31 Kai Yao , Kaizhu Huang , Jie Sun , Amir Hussain

Masked image modeling has been demonstrated as a powerful pretext task for generating robust representations that can be effectively generalized across multiple downstream tasks. Typically, this approach involves randomly masking patches…

Computer Vision and Pattern Recognition · Computer Science 2024-02-29 Neelu Madan , Nicolae-Catalin Ristea , Kamal Nasrollahi , Thomas B. Moeslund , Radu Tudor Ionescu

Due to its superior efficiency in utilizing annotations and addressing gigapixel-sized images, multiple instance learning (MIL) has shown great promise as a framework for whole slide image (WSI) classification in digital pathology…

Quantitative Methods · Quantitative Biology 2023-07-14 Qiehe Sun , Jiawen Li , Jin Xu , Junru Cheng , Tian Guan , Yonghong He

We address the problem of automated nuclear segmentation, classification, and quantification from Haematoxylin and Eosin stained histology images, which is of great relevance for several downstream computational pathology applications. In…

Computer Vision and Pattern Recognition · Computer Science 2022-04-19 Lihao Liu , Chenyang Hong , Angelica I. Aviles-Rivero , Carola-Bibiane Schönlieb

Unsupervised image segmentation is an important task in many real-world scenarios where labelled data is of scarce availability. In this paper we propose a novel approach that harnesses recent advances in unsupervised learning using a…

Computer Vision and Pattern Recognition · Computer Science 2022-10-24 Moshe Eliasof , Nir Ben Zikri , Eran Treister

Masking strategies commonly employed in natural language processing are still underexplored in vision tasks such as concept learning, where conventional methods typically rely on full images. However, using masked images diversifies…

Computer Vision and Pattern Recognition · Computer Science 2025-11-14 Yuwei Sun , Lu Mi , Ippei Fujisawa , Ruiqiao Mei , Jimin Chen , Siyu Zhu , Ryota Kanai

There has been significant progress in Masked Image Modeling (MIM). Existing MIM methods can be broadly categorized into two groups based on the reconstruction target: pixel-based and tokenizer-based approaches. The former offers a simpler…

Computer Vision and Pattern Recognition · Computer Science 2023-08-02 Yuan Liu , Songyang Zhang , Jiacheng Chen , Zhaohui Yu , Kai Chen , Dahua Lin

For diagnosing melanoma, hematoxylin and eosin (H&E) stained tissue slides remains the gold standard. These images contain quantitative information in different magnifications. In the present study, we investigated whether deep…

Tissues and Organs · Quantitative Biology 2019-04-15 Peizhen Xie , Ke Zuo , Yu Zhang , Fangfang Li , Mingzhu Yin , Kai Lu

Text images are unique in their dual nature, encompassing both visual and linguistic information. The visual component encompasses structural and appearance-based features, while the linguistic dimension incorporates contextual and semantic…

Computer Vision and Pattern Recognition · Computer Science 2025-03-25 Yifei Zhang , Chang Liu , Jin Wei , Xiaomeng Yang , Yu Zhou , Can Ma , Xiangyang Ji

Conventional deep learning models deal with images one-by-one, requiring costly and time-consuming expert labeling in the field of medical imaging, and domain-specific restriction limits model generalizability. Visual in-context learning…

The success of language Transformers is primarily attributed to the pretext task of masked language modeling (MLM), where texts are first tokenized into semantically meaningful pieces. In this work, we study masked image modeling (MIM) and…

Computer Vision and Pattern Recognition · Computer Science 2022-01-28 Jinghao Zhou , Chen Wei , Huiyu Wang , Wei Shen , Cihang Xie , Alan Yuille , Tao Kong

Generally, microscopy image analysis in biology relies on the segmentation of individual nuclei, using a dedicated stained image, to identify individual cells. However stained nuclei have drawbacks like the need for sample preparation, and…

Image and Video Processing · Electrical Eng. & Systems 2022-11-08 Gendarme Mathieu , Lambert Annika M. , El Debs Bachir

Segmentation of nuclei regions from histological images is an important task for automated computer-aided analysis of histological images, particularly in the presence of impermissible color variation in the color appearance of stained…

Image and Video Processing · Electrical Eng. & Systems 2025-06-10 Suman Mahapatra , Pradipta Maji

Multiplexed tissue imaging measures dozens of protein markers per cell, yet most deep learning models still apply early channel fusion, assuming shared structure across markers. We investigate whether preserving marker independence,…

Computer Vision and Pattern Recognition · Computer Science 2025-12-18 Simon Gutwein , Arthur Longuefosse , Jun Seita , Sabine Taschner-Mandl , Roxane Licandro

Masked Image Modeling (MIM) has achieved impressive representative performance with the aim of reconstructing randomly masked images. Despite the empirical success, most previous works have neglected the important fact that it is…

Computer Vision and Pattern Recognition · Computer Science 2023-03-28 Junde Xu , Zikai Lin , Donghao Zhou , Yaodong Yang , Xiangyun Liao , Bian Wu , Guangyong Chen , Pheng-Ann Heng

Quantitative analysis of cell nuclei in microscopic images is an essential yet challenging source of biological and pathological information. The major challenge is accurate detection and segmentation of densely packed nuclei in images…

Quantitative Methods · Quantitative Biology 2019-11-14 Linqing Feng , Jun Ho Song , Jiwon Kim , Soomin Jeong , Jin Sung Park , Jinhyun Kim

The interactions between tumor cells and the tumor microenvironment (TME) dictate therapeutic efficacy of radiation and many systemic therapies in breast cancer. However, to date, there is not a widely available method to reproducibly…

How to learn discriminative video representation from unlabeled videos is challenging but crucial for video analysis. The latest attempts seek to learn a representation model by predicting the appearance contents in the masked regions.…

Computer Vision and Pattern Recognition · Computer Science 2023-03-24 Xinyu Sun , Peihao Chen , Liangwei Chen , Changhao Li , Thomas H. Li , Mingkui Tan , Chuang Gan
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