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We introduce an interacting particle system that models the spread of an epidemic in terms of heterogeneous diffusive dynamics, rather than exogenous contact and transmission rates at the population level as in classical compartmental…

Probability · Mathematics 2026-05-20 Eliana Fausti , Andreas Sojmark

This paper investigates the dynamics of infectious diseases with a non-exponentially distributed infectious period. This is achieved by considering a multi-stage infection model on networks. Using pairwise approximation with a standard…

Physics and Society · Physics 2015-11-23 N. Sherborne , K. B. Blyuss , I. Z. Kiss

Deterministic continuum models formulated in terms of non-local partial differential equations for the evolutionary dynamics of populations structured by phenotypic traits have been used recently to address open questions concerning the…

Populations and Evolution · Quantitative Biology 2020-10-14 Aleksandra Ardaševa , Robert A. Gatenby , Alexander R. A. Anderson , Helen M. Byrne , Philip K. Maini , Tommaso Lorenzi

Models of disease spreading are critical for predicting infection growth in a population and evaluating public health policies. However, standard models typically represent the dynamics of disease transmission between individuals using…

Physics and Society · Physics 2022-06-07 Christopher A. Browne , Daniel B. Amchin , Joanna Schneider , Sujit S. Datta

Coinfection phenomena are common in nature, yet there is a lack of analytical approaches for coinfection systems with a high number of circulating and interacting strains. In this paper, we investigated a coinfection SIS framework applied…

Populations and Evolution · Quantitative Biology 2026-02-06 Sten Madec , Nicola Cinardi , Erida Gjini

Existing studies comparing individual-based models of growing cell populations and their continuum counterparts have mainly focused on homogeneous populations, in which all cells have the same phenotypic characteristics. However,…

Populations and Evolution · Quantitative Biology 2022-06-06 Fiona R Macfarlane , Xinran Ruan , Tommaso Lorenzi

We introduce a minimal multiscale framework that links within-host virus dynamics to population-level SIRS epidemiology through explicit, bidirectional coupling. At the microscopic layer, a two variant quasispecies (master and mutant…

Dynamical Systems · Mathematics 2026-01-28 Juan C. Muñoz-Sánchez , J. Tomás Lázaro , Josep Sardanyés , Santiago F. Elena

Simple models of infectious diseases tend to assume random mixing of individuals, but real interactions are not random pairwise encounters: they occur within various types of gatherings such as workplaces, households, schools, and concerts,…

Human behavior plays a critical role in shaping epidemic trajectories. During health crises, people respond in diverse ways in terms of self-protection and adherence to recommended measures, largely reflecting differences in how individuals…

Physics and Society · Physics 2026-01-30 Fabio Mazza , Gabriele Ricci , Francesca Colaiori , Stefano Guarino , Sandro Meloni , Fabio Saracco

We present a methodology providing a one-directional link from within-host individual heterogeneity to population-level disease transmission dynamics. The methodology works in several steps. A within-host model is investigated numerically…

Populations and Evolution · Quantitative Biology 2026-05-19 Julien Arino , Morgan Craig , Clotilde Djuikem , Kang-Ling Liao , Stéphanie Portet

Risk-driven behavior provides a feedback mechanism through which individuals both shape and are collectively affected by an epidemic. We introduce a general and flexible compartmental model to study the effect of heterogeneity in the…

Capturing the structured mixing within a population is key to the reliable projection of infectious disease dynamics and hence informed control. Both heterogeneity in the number of contacts and age-structured mixing have been repeatedly…

Social and Information Networks · Computer Science 2026-03-17 Luke Murray Kearney , Emma L Davis , Matt J Keeling

It is well recognised that animal and plant pathogens form complex ecological communities of interacting organisms within their hosts. Although community ecology approaches have been applied to determine pathogen interactions at the…

To better predict the dynamics of epidemics such as COVID-19, it is important not only to investigate the network of local and long-range contagious contacts but also to understand the temporal dynamics of infectiousness and detectable…

Populations and Evolution · Quantitative Biology 2025-09-03 Miguel A. Cajahuanca Ricaldi , Yaroslav Ispolatov

In this paper, a susceptible-infected-susceptible (SIS) model with identical infectivity, where each node is assigned with the same capability of active contacts, $A$, at each time step, is presented. We found that on scale-free networks,…

Physics and Society · Physics 2007-05-23 Rui Yang , Jie Ren , Wen-Jie Bai , Tao Zhou , Ming-Feng Zhang , Bing-Hong Wang

We study a stochastic epidemic model with multiple patches (locations), where individuals in each patch are categorized into three compartments, Susceptible, Infected and Recovered/Removed, and may migrate from one patch to another in any…

Probability · Mathematics 2023-08-21 Guodong Pang , Etienne Pardoux

We develop a stochastic epidemic model progressing over dynamic networks, where infection rates are heterogeneous and may vary with individual-level covariates. The joint dynamics are modeled as a continuous-time Markov chain such that…

Methodology · Statistics 2021-12-16 Fan Bu , Allison E. Aiello , Alexander Volfovsky , Jason Xu

In this paper, we are concerned with two SIS epidemic reaction-diffusion models with mass action infection mechanism of the form $SI$, and study the spatial profile of population distribution as the movement rate of the infected individuals…

Analysis of PDEs · Mathematics 2023-01-04 Rui Peng , Zhi-an Wang , Guanghui Zhang , Maolin Zhou

It is essential to understand the dynamics of epidemics in the presence of coexisting pathogens. There are various phenomenon that can effect the dynamics. In this paper, we formulate a mathematical model using different assumptions to…

Populations and Evolution · Quantitative Biology 2021-11-02 S. Ghersheen , V. Kozlov , U. Wennergren

We consider the qualitative behavior of a mathematical model for transmission dynamics with two nonlinear stages of contagion. The proposed model is inspired by phenomena occurring in epidemiology (spread of infectious diseases) or social…

Dynamical Systems · Mathematics 2021-05-04 Julian Heidecke , Maria Vittoria Barbarossa