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Asymmetry is a crucial characteristic of bilateral mammograms (Bi-MG) when abnormalities are developing. It is widely utilized by radiologists for diagnosis. The question of 'what the symmetrical Bi-MG would look like when the asymmetrical…

Computer Vision and Pattern Recognition · Computer Science 2023-07-07 Xin Wang , Tao Tan , Yuan Gao , Luyi Han , Tianyu Zhang , Chunyao Lu , Regina Beets-Tan , Ruisheng Su , Ritse Mann

Symmetries (transformations by group actions) are present in many datasets, and leveraging them holds considerable promise for improving predictions in machine learning. In this work, we aim to understand when and how deep networks -- with…

Machine Learning · Computer Science 2025-06-27 Andrea Perin , Stephane Deny

Latent representations learned by neural networks often exhibit semantic structure, where concept similarity is reflected by geometric proximity in embedding space. However, comparing such spaces across models remains difficult: changes in…

Longitudinal MRIs are often used to capture the gradual deterioration of brain structure and function caused by aging or neurological diseases. Analyzing this data via machine learning generally requires a large number of ground-truth…

Computer Vision and Pattern Recognition · Computer Science 2021-06-21 Jiahong Ouyang , Qingyu Zhao , Ehsan Adeli , Edith V Sullivan , Adolf Pfefferbaum , Greg Zaharchuk , Kilian M Pohl

This paper introduces the Neural Differential Manifold (NDM), a novel neural network architecture that explicitly incorporates geometric structure into its fundamental design. Departing from conventional Euclidean parameter spaces, the NDM…

Machine Learning · Computer Science 2025-10-30 Di Zhang

We propose a method of aligning a source image to a target image, where the transform is specified by a dense vector field. The two images are encoded as feature hierarchies by siamese convolutional nets. Then a hierarchy of aligner modules…

Computer Vision and Pattern Recognition · Computer Science 2019-04-05 Eric Mitchell , Stefan Keselj , Sergiy Popovych , Davit Buniatyan , H. Sebastian Seung

Neuroimaging biomarkers that distinguish between typical brain aging and Alzheimer's disease (AD) are valuable for determining how much each contributes to cognitive decline. Machine learning models can derive multi-variate brain change…

Diagnosing Autism Spectrum Disorder (ASD) is a challenging problem, and is based purely on behavioral descriptions of symptomology (DSM-5/ICD-10), and requires informants to observe children with disorder across different settings (e.g.…

Neurons and Cognition · Quantitative Biology 2020-03-04 Taban Eslami , Joseph S. Raiker , Fahad Saeed

Statistical shape modeling (SSM) directly from 3D medical images is an underutilized tool for detecting pathology, diagnosing disease, and conducting population-level morphology analysis. Deep learning frameworks have increased the…

Computer Vision and Pattern Recognition · Computer Science 2022-05-17 Jadie Adams , Shireen Elhabian

Deep learning has been successfully applied to human activity recognition. However, training deep neural networks requires explicitly labeled data which is difficult to acquire. In this paper, we present a model with multiple siamese…

Human-Computer Interaction · Computer Science 2023-07-19 Taoran Sheng , Manfred Huber

Recent advances in deep learning have improved the segmentation accuracy of subcortical brain structures, which would be useful in neuroimaging studies of many neurological disorders. However, most of the previous deep learning work does…

Computer Vision and Pattern Recognition · Computer Science 2019-02-21 Yilin Liu , Gengyan Zhao , Brendon M. Nacewicz , Nagesh Adluru , Gregory R. Kirk , Peter A Ferrazzano , Martin Styner , Andrew L. Alexander

In neuroscience, functional brain connectivity describes the connectivity between brain regions that share functional properties. Neuroscientists often characterize it by a time series of covariance matrices between functional measurements…

Methodology · Statistics 2019-07-09 Zhenhua Lin , Dehan Kong , Qiang Sun

Alterations in structural brain laterality are reported in attention-deficit/hyperactivity disorder (ADHD). However, few studies examined differences within presentations of ADHD. We investigate asymmetry index (AI) across 13 subcortical…

Neurons and Cognition · Quantitative Biology 2020-10-27 Cintya Nirvana Dutta , Pamela K. Douglas , Hernando Ombao

With the development of medical imaging technology, medical images have become an important basis for doctors to diagnose patients. The brain structure in the collected data is complicated, thence, doctors are required to spend plentiful…

Image and Video Processing · Electrical Eng. & Systems 2020-07-10 Nan Wang , Chengwei Chen , Yuan Xie , Lizhuang Ma

Learning the manifold structure of remote sensing images is of paramount relevance for modeling and understanding processes, as well as to encapsulate the high dimensionality in a reduced set of informative features for subsequent…

Computer Vision and Pattern Recognition · Computer Science 2022-05-04 Gulsen Taskin , Gustau Camps-Valls

Anomaly detection consists in identifying, within a dataset, those samples that significantly differ from the majority of the data, representing the normal class. It has many practical applications, e.g. ranging from defective product…

Computer Vision and Pattern Recognition · Computer Science 2020-11-13 Pankaj Mishra , Claudio Piciarelli , Gian Luca Foresti

While the prevalence of Autism Spectrum Disorder (ASD) is increasing, research continues in an effort to identify common etiological and pathophysiological bases. In this regard, modern machine learning and network science pave the way for…

Image and Video Processing · Electrical Eng. & Systems 2020-08-06 Sarah Itani , Dorina Thanou

A robust and informative local shape descriptor plays an important role in mesh registration. In this regard, spectral descriptors that are based on the spectrum of the Laplace-Beltrami operator have been a popular subject of research for…

Graphics · Computer Science 2019-10-21 Zhiyu Sun , Yusen He , Andrey Gritsenko , Amaury Lendasse , Stephen Baek

Brain morphology is shaped by genetic and mechanical factors and is linked to biological development and diseases. Its fractal-like features, regional anisotropy, and complex curvature distributions hinder quantitative insights in medical…

Neurons and Cognition · Quantitative Biology 2025-09-09 Yingjie Zhao , Yicheng Song , Fan Xu , Zhiping Xu

Deep unsupervised anomaly detection in brain magnetic resonance imaging offers a promising route to identify pathological deviations without requiring lesion-specific annotations. Yet, fragmented evaluations, heterogeneous datasets, and…

Computer Vision and Pattern Recognition · Computer Science 2025-12-02 Alexander Frotscher , Christian F. Baumgartner , Thomas Wolfers
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