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Brain imaging of mental health, neurodevelopmental and learning disorders has coupled with machine learning to identify patients based only on their brain activation, and ultimately identify features that generalize from smaller samples of…

Image and Video Processing · Electrical Eng. & Systems 2020-07-21 Laura Tomaz Da Silva , Nathalia Bianchini Esper , Duncan D. Ruiz , Felipe Meneguzzi , Augusto Buchweitz

Pathological brain appearances may be so heterogeneous as to be intelligible only as anomalies, defined by their deviation from normality rather than any specific pathological characteristic. Amongst the hardest tasks in medical imaging,…

Image and Video Processing · Electrical Eng. & Systems 2021-02-24 Walter Hugo Lopez Pinaya , Petru-Daniel Tudosiu , Robert Gray , Geraint Rees , Parashkev Nachev , Sebastien Ourselin , M. Jorge Cardoso

For the brain to recognize local orientations within images, neurons must spontaneously break the translation and rotation symmetry of their response functions -- an archetypal example of unsupervised learning. The dominant framework for…

Neurons and Cognition · Quantitative Biology 2021-09-07 Francesco Fumarola , Bettina Hein , Kenneth D. Miller

Unsupervised anomaly detection in brain imaging is challenging. In this paper, we propose self-supervised masked mesh learning for unsupervised anomaly detection on 3D cortical surfaces. Our framework leverages the intrinsic geometry of the…

Image and Video Processing · Electrical Eng. & Systems 2025-04-01 Hao-Chun Yang , Sicheng Dai , Saige Rutherford , Christian Gaser , Andre F Marquand , Christian F Beckmann , Thomas Wolfers

In clinical practice, medical segmentation datasets are often limited and heterogeneous, with variations in modalities, protocols, and anatomical targets across institutions. Existing deep learning models struggle to jointly learn from such…

Computer Vision and Pattern Recognition · Computer Science 2026-01-22 Weiwei Ma , Xiaobing Yu , Peijie Qiu , Jin Yang , Pan Xiao , Xiaoqi Zhao , Xiaofeng Liu , Tomo Miyazaki , Shinichiro Omachi , Yongsong Huang

Hippocampal atrophy in Alzheimer's disease (AD) is asymmetric and spatially inhomogeneous. While extensive work has been done on volume and shape analysis of atrophy of the hippocampus in AD, less attention has been given to hippocampal…

Image and Video Processing · Electrical Eng. & Systems 2024-09-20 Shen Zhu , Ifrah Zawar , Jaideep Kapur , P. Thomas Fletcher

Synthetic training has recently advanced brain MRI segmentation by enabling contrast-agnostic models trained entirely on generated data. However, most existing approaches rely on hundreds of automatically labeled templates, introducing…

Computer Vision and Pattern Recognition · Computer Science 2026-05-05 Romain Valabregue , Ines Khemir , Eric Badinet , François Rousseau , Guillaume Auzias , Reuben Dorent

We explore encoding brain symmetry into a neural network for a brain tumor segmentation task. A healthy human brain is symmetric at a high level of abstraction, and the high-level asymmetric parts are more likely to be tumor regions. Paying…

Computer Vision and Pattern Recognition · Computer Science 2017-11-20 Hejia Zhang , Xia Zhu , Theodore L. Willke

To study neurodegenerative diseases, longitudinal studies are carried on volunteer patients. During a time span of several months to several years, they go through regular medical visits to acquire data from different modalities, such as…

Computer Vision and Pattern Recognition · Computer Science 2020-11-03 Cecilia Ostertag , Marie Beurton-Aimar , Muriel Visani , Thierry Urruty , Karell Bertet

Human bodies exhibit various shapes for different identities or poses, but the body shape has certain similarities in structure and thus can be embedded in a low-dimensional space. This paper presents an autoencoder-like network…

Computer Vision and Pattern Recognition · Computer Science 2020-04-20 Boyi Jiang , Juyong Zhang , Jianfei Cai , Jianmin Zheng

Radiomic representations can quantify properties of regions of interest in medical image data. Classically, they account for pre-defined statistics of shape, texture, and other low-level image features. Alternatively, deep learning-based…

Computer Vision and Pattern Recognition · Computer Science 2021-07-14 Hongwei Li , Fei-Fei Xue , Krishna Chaitanya , Shengda Luo , Ivan Ezhov , Benedikt Wiestler , Jianguo Zhang , Bjoern Menze

Catastrophic forgetting is a critical challenge in training deep neural networks. Although continual learning has been investigated as a countermeasure to the problem, it often suffers from the requirements of additional network components…

Machine Learning · Computer Science 2019-10-23 Dongmin Park , Seokil Hong , Bohyung Han , Kyoung Mu Lee

Melanoma brain metastases (MBM) are common and spatially heterogeneous lesions, complicating cohort-level analyses due to anatomical variability and differing MRI protocols. We propose a fully differentiable, deep-learning-based deformable…

Computer Vision and Pattern Recognition · Computer Science 2026-02-16 Nanna E. Wielenberg , Ilinca Popp , Oliver Blanck , Lucas Zander , Jan C. Peeken , Stephanie E. Combs , Anca-Ligia Grosu , Dimos Baltas , Tobias Fechter

The differential diagnosis of neurodegenerative diseases, characterized by overlapping symptoms, may be challenging. Brain imaging coupled with artificial intelligence has been previously proposed for diagnostic support, but most of these…

Image and Video Processing · Electrical Eng. & Systems 2025-02-21 Pierrick Coupé , Boris Mansencal , José V. Manjón , Patrice Péran , Wassilios G. Meissner , Thomas Tourdias , Vincent Planche

Brain lesions, including stroke and tumours, have a high degree of variability in terms of location, size, intensity and form, making automatic segmentation difficult. We propose an improvement to existing segmentation methods by exploiting…

Image and Video Processing · Electrical Eng. & Systems 2019-07-22 Kevin Raina , Uladzimir Yahorau , Tanya Schmah

Autism Spectrum Disorder(ASD) is a set of neurodevelopmental conditions that affect patients' social abilities. In recent years, many studies have employed deep learning to diagnose this brain dysfunction through functional MRI (fMRI).…

Image and Video Processing · Electrical Eng. & Systems 2021-10-26 Li Pan , Jundong Liu , Mingqin Shi , Chi Wah Wong , Kei Hang Katie Chan

Machine learning-based medical anomaly detection is an important problem that has been extensively studied. Numerous approaches have been proposed across various medical application domains and we observe several similarities across these…

Machine Learning · Computer Science 2021-04-14 Tharindu Fernando , Harshala Gammulle , Simon Denman , Sridha Sridharan , Clinton Fookes

Anomaly detection on attributed networks aims at finding nodes whose patterns deviate significantly from the majority of reference nodes, which is pervasive in many applications such as network intrusion detection and social spammer…

Machine Learning · Computer Science 2020-02-13 Haoyi Fan , Fengbin Zhang , Zuoyong Li

Quantifying similarity between neural representations -- e.g. hidden layer activation vectors -- is a perennial problem in deep learning and neuroscience research. Existing methods compare deterministic responses (e.g. artificial networks…

Machine Learning · Computer Science 2023-02-07 Lyndon R. Duong , Jingyang Zhou , Josue Nassar , Jules Berman , Jeroen Olieslagers , Alex H. Williams

We develop a Bayesian bivariate spatial model for multivariate regression analysis applicable to studies examining the influence of genetic variation on brain structure. Our model is motivated by an imaging genetics study of the Alzheimer's…

Methodology · Statistics 2020-05-26 Yin Song , Shufei Ge , Jiguo Cao , Liangliang Wang , Farouk S. Nathoo