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Cell instance segmentation is a fundamental task in digital pathology with broad clinical applications. Recently, vision foundation models, which are predominantly based on Vision Transformers (ViTs), have achieved remarkable success in…

Computer Vision and Pattern Recognition · Computer Science 2025-04-02 Yang Yang , Xijie Xu , Yixun Zhou , Jie Zheng

In pathology, accurate and efficient analysis of Hematoxylin and Eosin (H\&E) slides is crucial for timely and effective cancer diagnosis. Although many deep learning solutions for nuclei instance segmentation and classification exist in…

Image and Video Processing · Electrical Eng. & Systems 2024-08-12 Cristian Tommasino , Cristiano Russo , Antonio Maria Rinaldi

Digital Pathology is a cornerstone in the diagnosis and treatment of diseases. A key task in this field is the identification and segmentation of cells in hematoxylin and eosin-stained images. Existing methods for cell segmentation often…

Computer Vision and Pattern Recognition · Computer Science 2025-01-10 Fabian Hörst , Moritz Rempe , Helmut Becker , Lukas Heine , Julius Keyl , Jens Kleesiek

Skin cancer is a global health concern, necessitating early and accurate diagnosis for improved patient outcomes. This study introduces a groundbreaking approach to skin cancer classification, employing the Vision Transformer, a…

Image and Video Processing · Electrical Eng. & Systems 2024-01-11 Galib Muhammad Shahriar Himel , Md. Masudul Islam , Kh Abdullah Al-Aff , Shams Ibne Karim , Md. Kabir Uddin Sikder

Automatic nuclei segmentation and classification play a vital role in digital pathology. However, previous works are mostly built on data with limited diversity and small sizes, making the results questionable or misleading in actual…

Image and Video Processing · Electrical Eng. & Systems 2023-05-31 Kai Yao , Kaizhu Huang , Jie Sun , Amir Hussain

Accurate and scalable cancer diagnosis remains a critical challenge in modern pathology, particularly for malignancies such as breast, prostate, bone, and cervical, which exhibit complex histological variability. In this study, we propose a…

Image and Video Processing · Electrical Eng. & Systems 2025-08-18 Faisal Ahmed

Accurate and efficient cell nuclei detection and classification in histopathological Whole Slide Images (WSIs) are pivotal for digital pathology applications. Traditional cell segmentation approaches, while commonly used, are…

Computer Vision and Pattern Recognition · Computer Science 2025-02-11 Oscar Pina , Eduard Dorca , Verónica Vilaplana

Automatic tissue segmentation and nuclei detection is an important task in pathology, aiding in biomarker extraction and discovery. The panoptic segmentation of nuclei and tissue in advanced melanoma (PUMA) challenge aims to improve tissue…

Computer Vision and Pattern Recognition · Computer Science 2025-03-18 Negar Shahamiri , Moritz Rempe , Lukas Heine , Jens Kleesiek , Fabian Hörst

Skin cancer detection still represents a major challenge in healthcare. Common detection methods can be lengthy and require human assistance which falls short in many countries. Previous research demonstrates how convolutional neural…

Computer Vision and Pattern Recognition · Computer Science 2024-08-27 Carolin Flosdorf , Justin Engelker , Igor Keller , Nicolas Mohr

Accurate nuclei segmentation is an essential foundation for various applications in computational pathology, including cancer diagnosis and treatment planning. Even slight variations in nuclei representations can significantly impact these…

Image and Video Processing · Electrical Eng. & Systems 2024-07-30 Zunaira Rauf , Abdul Rehman Khan , Asifullah Khan

Cell instance segmentation in fluorescence microscopy images is becoming essential for cancer dynamics and prognosis. Data extracted from cancer dynamics allows to understand and accurately model different metabolic processes such as…

The segmentation of cell nuclei in tissue images stained with the blood dye hematoxylin and eosin (H$\&$E) is essential for various clinical applications and analyses. Due to the complex characteristics of cellular morphology, a large…

Image and Video Processing · Electrical Eng. & Systems 2024-07-26 Ziwei Cui , Jingfeng Yao , Lunbin Zeng , Juan Yang , Wenyu Liu , Xinggang Wang

Identify the cells' nuclei is the important point for most medical analyses. To assist doctors finding the accurate cell' nuclei location automatically is highly demanded in the clinical practice. Recently, fully convolutional neural…

Computer Vision and Pattern Recognition · Computer Science 2019-11-25 Tianyang Zhang , Rui Ma

Nuclear segmentation and classification within Haematoxylin & Eosin stained histology images is a fundamental prerequisite in the digital pathology work-flow. The development of automated methods for nuclear segmentation and classification…

Computer Vision and Pattern Recognition · Computer Science 2019-11-14 Simon Graham , Quoc Dang Vu , Shan E Ahmed Raza , Ayesha Azam , Yee Wah Tsang , Jin Tae Kwak , Nasir Rajpoot

The emergence of Vision Transformers (ViTs) has revolutionized computer vision, yet their effectiveness compared to traditional Convolutional Neural Networks (CNNs) in medical imaging remains under-explored. This study presents a…

Image and Video Processing · Electrical Eng. & Systems 2025-07-30 Kunal Kawadkar

Medical image segmentation plays a crucial role in various healthcare applications, enabling accurate diagnosis, treatment planning, and disease monitoring. Traditionally, convolutional neural networks (CNNs) dominated this domain,…

We propose a 3D convolutional neural network to simultaneously segment and detect cell nuclei in confocal microscopy images. Mirroring the co-dependency of these tasks, our proposed model consists of two serial components: the first part…

Image and Video Processing · Electrical Eng. & Systems 2018-09-07 Sundaresh Ram , Vicky T. Nguyen , Kirsten H. Limesand , Mert R. Sabuncu

Cell detection in microscopy images is important to study how cells move and interact with their environment. Most recent deep learning-based methods for cell detection use convolutional neural networks (CNNs). However, inspired by the…

Image and Video Processing · Electrical Eng. & Systems 2022-06-15 Royden Wagner , Karl Rohr

Nuclei instance segmentation in hematoxylin and eosin (H&E)-stained images plays an important role in automated histological image analysis, with various applications in downstream tasks. While several machine learning and deep learning…

Computer Vision and Pattern Recognition · Computer Science 2026-01-29 Nima Torbati , Anastasia Meshcheryakova , Ramona Woitek , Sepideh Hatamikia , Diana Mechtcheriakova , Amirreza Mahbod

Skin cancer is a treatable disease if discovered early. We provide a production-specific solution to the skin cancer classification problem that matches human performance in melanoma identification by training a vision transformer on…

Computer Vision and Pattern Recognition · Computer Science 2023-08-21 Vlad-Constantin Lungu-Stan , Dumitru-Clementin Cercel , Florin Pop
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