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Histopathology remains the gold standard for cancer diagnosis because it provides detailed cellular-level assessment of tissue morphology. However, manual histopathological examination is time-consuming, labour-intensive, and subject to…

Computer Vision and Pattern Recognition · Computer Science 2026-03-13 Ravi Mosalpuri , Mohammed Abdelsamea , Ahmed Karam Eldaly

Nuclear segmentation, classification and quantification within Haematoxylin & Eosin stained histology images enables the extraction of interpretable cell-based features that can be used in downstream explainable models in computational…

Image and Video Processing · Electrical Eng. & Systems 2022-02-25 Satoshi Kondo , Satoshi Kasai

With the rapid development of deep learning, CNN-based U-shaped networks have succeeded in medical image segmentation and are widely applied for various tasks. However, their limitations in capturing global features hinder their performance…

Image and Video Processing · Electrical Eng. & Systems 2024-10-22 Xin Li , Wenhui Zhu , Xuanzhao Dong , Oana M. Dumitrascu , Yalin Wang

Manual Pap smear analysis for cervical cancer screening is limited by inter-observer variability, time constraints, and restricted expert availability. Although convolutional neural networks (CNNs) have automated cervical cell…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Nisreen Albzour , Sarah S. Lam

Instance segmentation and classification of nuclei is an important task in computational pathology. We show that StarDist, a deep learning nuclei segmentation method originally developed for fluorescence microscopy, can be extended and…

Computer Vision and Pattern Recognition · Computer Science 2022-08-22 Martin Weigert , Uwe Schmidt

Skin cancer is a common and fast rising malignancy worldwide. Early detection is critical for improving outcomes. Deep learning models trained on dermoscopic and clinical images can support automated and fast triage. However, many studies…

Computer Vision and Pattern Recognition · Computer Science 2026-05-27 Durjoy Dey , Yuhong Yan , Hassan Hajjdiab

Cell nuclei instance segmentation is a crucial task in digital kidney pathology. Traditional automatic segmentation methods often lack generalizability when applied to unseen datasets. Recently, the success of foundation models (FMs) has…

Accurate skin-lesion segmentation remains a key technical challenge for computer-aided diagnosis of skin cancer. Convolutional neural networks, while effective, are constrained by limited receptive fields and thus struggle to model…

Computer Vision and Pattern Recognition · Computer Science 2025-09-04 Pengyang Yu , Haoquan Wang , Gerard Marks , Tahar Kechadi , Laurence T. Yang , Sahraoui Dhelim , Nyothiri Aung

Deep learning models are increasingly utilized on resource-constrained edge devices for real-time data analytics. Recently, Vision Transformer and their variants have shown exceptional performance in various computer vision tasks. However,…

Computer Vision and Pattern Recognition · Computer Science 2025-05-22 Xiang Liu , Yijun Song , Xia Li , Yifei Sun , Huiying Lan , Zemin Liu , Linshan Jiang , Jialin Li

Cell and nucleus segmentation are fundamental tasks for quantitative bioimage analysis. Despite progress in recent years, biologists and other domain experts still require novel algorithms to handle increasingly large and complex real-world…

Computer Vision and Pattern Recognition · Computer Science 2024-08-29 Thibaut Goldsborough , Ben Philps , Alan O'Callaghan , Fiona Inglis , Leo Leplat , Andrew Filby , Hakan Bilen , Peter Bankhead

Nuclei appear small in size, yet, in real clinical practice, the global spatial information and correlation of the color or brightness contrast between nuclei and background, have been considered a crucial component for accurate nuclei…

Image and Video Processing · Electrical Eng. & Systems 2023-07-18 Zhenqi He , Mathias Unberath , Jing Ke , Yiqing Shen

Accurate nuclei segmentation in histopathological images is crucial for cancer diagnosis. Automating this process offers valuable support to clinical experts, as manual annotation is time-consuming and prone to human errors. However,…

Computer Vision and Pattern Recognition · Computer Science 2024-06-13 Ayush Roy , Payel Pramanik , Dmitrii Kaplun , Sergei Antonov , Ram Sarkar

Histological subtype of papillary (p) renal cell carcinoma (RCC), type 1 vs. type 2, is an essential prognostic factor. The two subtypes of pRCC have a similar pattern, i.e., the papillary architecture, yet some subtle differences,…

Computer Vision and Pattern Recognition · Computer Science 2021-06-24 Zeyu Gao , Bangyang Hong , Xianli Zhang , Yang Li , Chang Jia , Jialun Wu , Chunbao Wang , Deyu Meng , Chen Li

Masked image modelling (MIM) is a powerful self-supervised representation learning paradigm, whose potential has not been widely demonstrated in medical image analysis. In this work, we show the capacity of MIM to capture rich semantic…

Computer Vision and Pattern Recognition · Computer Science 2023-06-30 Piotr Wójcik , Hussein Naji , Adrian Simon , Reinhard Büttner , Katarzyna Bożek

Accurate grading of corn kernels is critical for seed certification, directional seeding, and breeding, yet it is still predominantly performed by manual inspection. This work introduces CornViT, a three-stage Convolutional Vision…

Computer Vision and Pattern Recognition · Computer Science 2026-01-06 Sai Teja Erukude , Jane Mascarenhas , Lior Shamir

This study evaluates the effectiveness of deep learning models in classifying histopathological images for early and accurate detection of breast cancer. Eight advanced models, including ResNet-50, DenseNet-121, ResNeXt-50, Vision…

Image and Video Processing · Electrical Eng. & Systems 2025-05-09 Sania Eskandari , Ali Eslamian , Nusrat Munia , Amjad Alqarni , Qiang Cheng

Numerous deep learning based methods have been developed for nuclei segmentation for H&E images and have achieved close to human performance. However, direct application of such methods to another modality of images, such as…

Computer Vision and Pattern Recognition · Computer Science 2022-08-15 Roger Trullo , Quoc-Anh Bui , Qi Tang , Reza Olfati-Saber

In computational pathology, automatic nuclei instance segmentation plays an essential role in whole slide image analysis. While many computerized approaches have been proposed for this task, supervised deep learning (DL) methods have shown…

Image and Video Processing · Electrical Eng. & Systems 2023-08-04 Amirreza Mahbod , Christine Polak , Katharina Feldmann , Rumsha Khan , Katharina Gelles , Georg Dorffner , Ramona Woitek , Sepideh Hatamikia , Isabella Ellinger

Nuclei segmentation and classification is the first and most crucial step that is utilized for many different microscopy medical analysis applications. However, it suffers from many issues such as the segmentation of small objects,…

Image and Video Processing · Electrical Eng. & Systems 2022-03-07 Hussam Azzuni , Muhammad Ridzuan , Min Xu , Mohammad Yaqub

Detecting and segmenting object instances is a common task in biomedical applications. Examples range from detecting lesions on functional magnetic resonance images, to the detection of tumours in histopathological images and extracting…

Computer Vision and Pattern Recognition · Computer Science 2021-04-12 Tim Prangemeier , Christoph Reich , Heinz Koeppl