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Related papers: DNABERT-2: Efficient Foundation Model and Benchmar…

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Tokenization is the first step in modern neural language model pipelines where an input text is converted to a sequence of subword tokens. We introduce from first principles a finite-state transduction framework which can efficiently encode…

Computation and Language · Computer Science 2024-10-22 Marco Cognetta , Naoaki Okazaki

We now need more than ever to make genome analysis more intelligent. We need to read, analyze, and interpret our genomes not only quickly, but also accurately and efficiently enough to scale the analysis to population level. There currently…

Transformer-based models have achieved dominant performance in numerous NLP tasks. Despite their remarkable successes, pre-trained transformers such as BERT suffer from a computationally expensive self-attention mechanism that interacts…

Computation and Language · Computer Science 2024-06-04 Jungmin Yun , Mihyeon Kim , Youngbin Kim

Background: Advances in high throughput sequencing technologies provide a huge number of genomes to be analyzed. Thus, computational methods play a crucial role in analyzing and extracting knowledge from the data generated. Investigating…

Encoder-only transformers remain indispensable in retrieval, classification, and ranking systems where latency, stability, and cost are paramount. Most general purpose encoders, however, are trained on generic corpora with limited coverage…

Computation and Language · Computer Science 2026-02-05 Rahul Bajaj , Anuj Garg

We propose a novel neural architecture named TextGraphFuseGAT, which integrates a pretrained transformer encoder (PhoBERT) with Graph Attention Networks for token-level classification tasks. The proposed model constructs a fully connected…

Computation and Language · Computer Science 2025-10-14 Ba-Quang Nguyen

To handle the scarcity and heterogeneity of electroencephalography (EEG) data for Brain-Computer Interface (BCI) tasks, and to harness the power of large publicly available data sets, we propose Neuro-GPT, a foundation model consisting of…

Machine Learning · Computer Science 2024-03-05 Wenhui Cui , Woojae Jeong , Philipp Thölke , Takfarinas Medani , Karim Jerbi , Anand A. Joshi , Richard M. Leahy

The predictions of question answering (QA)systems are typically evaluated against manually annotated finite sets of one or more answers. This leads to a coverage limitation that results in underestimating the true performance of systems,…

Computation and Language · Computer Science 2022-10-27 Jannis Bulian , Christian Buck , Wojciech Gajewski , Benjamin Boerschinger , Tal Schuster

Byte pair encoding (BPE) emerges as an effective tokenization method for tackling the out-of-vocabulary (OOV) challenge in various natural language and speech processing tasks. Recent research highlights the dependency of BPE subword…

Computation and Language · Computer Science 2024-01-30 Ahnaf Mozib Samin

Open Named Entity Recognition (NER), which involves identifying arbitrary types of entities from arbitrary domains, remains challenging for Large Language Models (LLMs). Recent studies suggest that fine-tuning LLMs on extensive NER data can…

The HeartBert model is introduced with three primary objectives: reducing the need for labeled data, minimizing computational resources, and simultaneously improving performance in machine learning systems that analyze Electrocardiogram…

Signal Processing · Electrical Eng. & Systems 2026-04-29 Saedeh Tahery , Fatemeh Hamid Akhlaghi , Termeh Amirsoleimani

Tokenization is an important text preprocessing step to prepare input tokens for deep language models. WordPiece and BPE are de facto methods employed by important models, such as BERT and GPT. However, the impact of tokenization can be…

Computation and Language · Computer Science 2023-03-28 Cagri Toraman , Eyup Halit Yilmaz , Furkan Şahinuç , Oguzhan Ozcelik

State-of-the-art language models are autoregressive and operate on subword units known as tokens. Specifically, one must encode the conditioning string into a list of tokens before passing to the language models for next-token prediction.…

Computation and Language · Computer Science 2024-07-09 Buu Phan , Marton Havasi , Matthew Muckley , Karen Ullrich

Foundation models have made significant strides in understanding the genomic language of DNA sequences. However, previous models typically adopt the tokenization methods designed for natural language, which are unsuitable for DNA sequences…

Genomics · Quantitative Biology 2024-12-19 Lifeng Qiao , Peng Ye , Yuchen Ren , Weiqiang Bai , Chaoqi Liang , Xinzhu Ma , Nanqing Dong , Wanli Ouyang

We pretrain METAGENE-1, a 7-billion-parameter autoregressive transformer model, which we refer to as a metagenomic foundation model, on a novel corpus of diverse metagenomic DNA and RNA sequences comprising over 1.5 trillion base pairs.…

Genomics · Quantitative Biology 2025-01-07 Ollie Liu , Sami Jaghouar , Johannes Hagemann , Shangshang Wang , Jason Wiemels , Jeff Kaufman , Willie Neiswanger

The emergence of Next Generation Sequencing (NGS) platforms has increased the throughput of genomic sequencing and in turn the amount of data that needs to be processed, requiring highly efficient computation for its analysis. In this…

Distributed, Parallel, and Cluster Computing · Computer Science 2017-12-12 Nicola Cadenelli , Jorda Polo , David Carrera

Recent advances in the area of long document matching have primarily focused on using transformer-based models for long document encoding and matching. There are two primary challenges associated with these models. Firstly, the performance…

Computation and Language · Computer Science 2023-02-09 Akshita Jha , Adithya Samavedhi , Vineeth Rakesh , Jaideep Chandrashekar , Chandan K. Reddy

Identification of cancer driver genes is fundamental for the development of targeted therapeutic interventions. The integration of mutational profiles with protein-protein interaction (PPI) networks offers a promising avenue for their…

Quantum Physics · Physics 2025-11-05 Patricia Marques , Andreas Wichert , Duarte Magano , Bruno Coutinho

Gene finding is the task of identifying the locations of coding sequences within the vast amount of genetic code contained in the genome. With an ever increasing quantity of raw genome sequences, gene finding is an important avenue towards…

Genomics · Quantitative Biology 2025-05-07 Frederikke I. Marin , Dennis Pultz , Wouter Boomsma

Deep learning research for binary analysis faces a critical infrastructure gap. Today, existing datasets target single platforms, require specialized tooling, or provide only hand-engineered features incompatible with modern neural…

Cryptography and Security · Computer Science 2025-12-01 Michael J. Bommarito