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In high-dimensional genomic data, the curse of dimensionality (d >> n) and limited sampling make feature selection inherently unstable - a critical barrier to biomarker discovery. We introduce StackFeat, an iterative algorithm that…

Other Quantitative Biology · Quantitative Biology 2026-04-28 Akbar Yermekov , D. A. Herrera-Martí

Tokenization is associated with many poorly understood shortcomings in language models (LMs), yet remains an important component for long sequence scaling purposes. This work studies how tokenization impacts model performance by analyzing…

Computation and Language · Computer Science 2025-04-15 Buu Phan , Brandon Amos , Itai Gat , Marton Havasi , Matthew Muckley , Karen Ullrich

Neural program embedding can be helpful in analyzing large software, a task that is challenging for traditional logic-based program analyses due to their limited scalability. A key focus of recent machine-learning advances in this area is…

Machine Learning · Computer Science 2019-05-29 Ke Wang , Mihai Christodorescu

In biomedical natural language processing, named entity recognition (NER) and named entity normalization (NEN) are key tasks that enable the automatic extraction of biomedical entities (e.g. diseases and drugs) from the ever-growing…

Computation and Language · Computer Science 2022-10-07 Mujeen Sung , Minbyul Jeong , Yonghwa Choi , Donghyeon Kim , Jinhyuk Lee , Jaewoo Kang

The analysis of biological sequencing data has been one of the biggest applications of string algorithms. The approaches used in many such applications are based on the analysis of k-mers, which are short fixed-length strings present in a…

Data Structures and Algorithms · Computer Science 2020-06-15 Rayan Chikhi , Jan Holub , Paul Medvedev

Exploring the predictive capabilities of language models in material science is an ongoing interest. This study investigates the application of language model embeddings to enhance material property prediction in materials science. By…

Computation and Language · Computer Science 2024-11-05 Yuwei Wan , Tong Xie , Nan Wu , Wenjie Zhang , Chunyu Kit , Bram Hoex

While large general-purpose Transformer-based encoders excel at general language understanding, their performance diminishes in specialized domains like manufacturing due to a lack of exposure to domain-specific terminology and semantics.…

Computation and Language · Computer Science 2025-11-10 Robin Armingaud , Romaric Besançon

This study introduces a novel knowledge enhanced tokenisation mechanism, K-Tokeniser, for clinical text processing. Technically, at initialisation stage, K-Tokeniser populates global representations of tokens based on semantic types of…

Computation and Language · Computer Science 2024-06-21 Abul Hasan , Jinge Wu , Quang Ngoc Nguyen , Salomé Andres , Imane Guellil , Huayu Zhang , Arlene Casey , Beatrice Alex , Bruce Guthrie , Honghan Wu

Entity resolution (ER) is the process of identifying records that refer to the same entities within one or across multiple databases. Numerous techniques have been developed to tackle ER challenges over the years, with recent emphasis…

Databases · Computer Science 2023-11-14 George Papadakis , Nishadi Kirielle , Peter Christen , Themis Palpanas

Nepali, a low-resource language spoken by over 32 million people, continues to face challenges in natural language processing (NLP) due to its complex grammar, agglutinative morphology, and limited availability of high-quality corpora. Most…

Computation and Language · Computer Science 2025-12-17 Adarsha Shrestha , Basanta Pokharel , Binit Shrestha , Smriti Adhikari , Dinesh Gothe

Metagenomics characterizes the taxonomic diversity of microbial communities by sequencing DNA directly from an environmental sample. One of the main challenges in metagenomics data analysis is the binning step, where each sequenced read is…

Quantitative Methods · Quantitative Biology 2015-05-27 Kévin Vervier , Pierre Mahé , Maud Tournoud , Jean-Baptiste Veyrieras , Jean-Philippe Vert

Knowledge graph (KG) embedding methods which map entities and relations to unique embeddings in the KG have shown promising results on many reasoning tasks. However, the same embedding dimension for both dense entities and sparse entities…

Computation and Language · Computer Science 2022-05-06 Linlin Chao , Xiexiong Lin , Taifeng Wang , Wei Chu

Named entity recognition (NER) stands as a fundamental and pivotal task within the realm of Natural Language Processing. Particularly within the domain of Biomedical Method NER, this task presents notable challenges, stemming from the…

Computation and Language · Computer Science 2024-07-01 Chen Tang , Bohao Yang , Kun Zhao , Bo Lv , Chenghao Xiao , Frank Guerin , Chenghua Lin

Autoregressive language models like GPT aim to predict next tokens, while autoencoding models such as BERT are trained on tasks such as predicting masked tokens. We train a decoder-only architecture for predicting the second to last token…

Computation and Language · Computer Science 2025-02-17 Johannes Schneider

Despite the availability of various sequence analysis models, comparative genomic analysis remains a challenge in genomics, genetics, and phylogenetics. Commutative algebra, a fundamental tool in algebraic geometry and number theory, has…

Quantitative Methods · Quantitative Biology 2025-08-14 Faisal Suwayyid , Yuta Hozumi , Hongsong Feng , Mushal Zia , JunJie Wee , Guo-Wei Wei

Bioinformatics tools have been developed to interpret gene expression data at the gene set level, and these gene set based analyses improve the biologists' capability to discover functional relevance of their experiment design. While…

Machine Learning · Statistics 2019-01-01 Hung-I Harry Chen , Yu-Chiao Chiu , Tinghe Zhang , Songyao Zhang , Yufei Huang , Yidong Chen

This research introduces a novel text generation model that combines BERT's semantic interpretation strengths with GPT-4's generative capabilities, establishing a high standard in generating coherent, contextually accurate language. Through…

Computation and Language · Computer Science 2024-11-20 Jiajing Chen , Shuo Wang , Zhen Qi , Zhenhong Zhang , Chihang Wang , Hongye Zheng

Computing the similarity between two DNA sequences is of vital importance in bioscience, yet it can be computationally expensive on classical hardware. For example, the edit distance with move operations (EDM), a DNA similarity measure of…

Quantum Physics · Physics 2025-12-03 Chenyu Shi , Gabriele Leoni , Mauro Petrillo , Antonio Puertas Gallardo , Hao Wang

Neurophysiological decoding, fundamental to advancing brain-computer interface (BCI) technologies, has significantly benefited from recent advances in deep learning. However, existing decoding approaches largely remain constrained to…

Signal Processing · Electrical Eng. & Systems 2025-08-07 Di Wu , Yifei Jia , Siyuan Li , Shiqi Zhao , Jie Yang , Mohamad Sawan
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