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Photoacoustic image (PAI) quality improvement using a low frequency piezoelectric micromachined ultrasound transducer (PMUT) having the fundamental resonant frequency 1 MHz is being reported. Specifically, three different methods are…

Instrumentation and Detectors · Physics 2022-12-01 Kaustav Roy , Arijit Paramanik , Souradip Paul , Akshay Kalyan , Eshani Sarkar , Anuj Ashok , Rudra Pratap , M Suheshkumar Singh

Quantitative photoacoustic computed tomography (qPACT) is a promising imaging modality for estimating physiological parameters such as blood oxygen saturation. However, developing robust qPACT reconstruction methods remains challenging due…

Medical Physics · Physics 2025-10-07 Refik Mert Cam , Seonyeong Park , Umberto Villa , Mark A. Anastasio

High-quality imaging in photoacoustic computed tomography (PACT) usually requires a high-channel count system for dense spatial sampling around the object to avoid aliasing-related artefacts. To reduce system complexity, various image…

Image and Video Processing · Electrical Eng. & Systems 2024-09-24 Bowei Yao , Shilong Cui , Haizhao Dai , Qing Wu , Youshen Xiao , Fei Gao , Jingyi Yu , Yuyao Zhang , Xiran Cai

Single Photon Emission Computed Tomography (SPECT) is a non-invasive imaging modality, frequently used in myocardial perfusion imaging. The biggest challenges facing the majority of clinical SPECT systems are low sensitivity, poor…

Medical Physics · Physics 2021-03-30 Narayan Bhusal

Photoacoustic imaging is an emerging imaging modality that is based upon the photoacoustic effect. In photoacoustic tomography (PAT), the induced acoustic pressure waves are measured by an array of detectors and used to reconstruct an image…

Computer Vision and Pattern Recognition · Computer Science 2019-04-26 Steven Guan , Amir Khan , Siddhartha Sikdar , Parag V. Chitnis

Photoacoustic (PA) imaging combines the high optical absorption contrast of optical imaging with the deep tissue penetration of ultrasound detection, offering great potential for functional imaging and disease diagnosis. However, current PA…

Optics · Physics 2026-01-29 Daohuai Jiang , Xuanxuan Ye , Hengrong Lan , Xianzeng Zhang , Fei Gao

Photoacoustic Tomography (PAT) is an emerging biomedical "imaging from coupled physics" technique, in which the image contrast is due to optical absorption, but the information is carried to the surface of the tissue as ultrasound pulses.…

Numerical Analysis · Mathematics 2016-11-03 Simon R. Arridge , Marta M. Betcke , Ben T. Cox , Felix Lucka , Brad E. Treeby

The correction of the aberration of transcranial focused ultrasounds is a relevant issue for enhancing various non-invasive medical treatments. Emission through multi-element phased arrays has been the most widely accepted method to reduce…

Medical Physics · Physics 2018-05-28 Marcelino Ferri , JM Bravo , Javier Redondo , JV Sánchez-Pérez

Photoacoustic imaging is a promising imaging technique for human brain due to its high sensitivity and functional imaging ability. However, the skull would cause strong attenuation and distortion to the photoacoustic signals, which makes…

Medical Physics · Physics 2023-02-22 Yuting Shen , Xiaohua Feng , Fei Gao

Photoacoustic microscopy (PAM) has been a promising biomedical imaging technology in recent years. However, the point-by-point scanning mechanism results in low-speed imaging, which limits the application of PAM. Reducing sampling density…

Image and Video Processing · Electrical Eng. & Systems 2020-06-09 Jiasheng Zhou , Da He , Xiaoyu Shang , Zhendong Guo , Sung-liang Chen , Jiajia Luo

The development of fast and accurate image reconstruction algorithms is a central aspect of computed tomography. In this paper, we investigate this issue for the sparse data problem in photoacoustic tomography (PAT). We develop a direct and…

Computer Vision and Pattern Recognition · Computer Science 2018-08-31 Stephan Antholzer , Markus Haltmeier , Johannes Schwab

Photoacoustic microscopy (PAM) is a novel implementation of photoacoustic imaging (PAI) for visualizing the 3D bio-structure, which is realized by raster scanning of the tissue. However, as three involved critical imaging parameters,…

Image and Video Processing · Electrical Eng. & Systems 2023-08-10 Zhengyuan Zhang , Haoran Jin , Zesheng Zheng , Wenwen Zhang , Wenhao Lu , Feng Qin , Arunima Sharma , Manojit Pramanik , Yuanjin Zheng

In photoacoustic tomography (PAT), the acoustic pressure waves produced by optical excitation are measured by an array of detectors and used to reconstruct an image. Sparse spatial sampling and limited-view detection are two common…

Image and Video Processing · Electrical Eng. & Systems 2021-04-08 Steven Guan , Ko-Tsung Hsu , Matthias Eyassu , Parag V. Chitnis

Photoacoustic imaging (PAI) is a novel hybrid imaging technique that combines the benefits of both optical and acoustic imaging modalities, which provides functional and molecular optical contrasts of deep tissue. Commonly used ultrasound…

Medical Physics · Physics 2025-09-24 Xiyu Chen , Junxiang Cai , Rui Zheng , Tao Wu , Fei Gao

Herein we report the first in-human transcranial imaging of brain function using photoacoustic computed tomography. Functional responses to benchmark motor tasks were imaged on both the skull-less and the skull-intact hemispheres of a…

Photoacoustic tomography (PAT) is a rapidly-evolving medical imaging modality that combines optical absorption contrast with ultrasound imaging depth. One challenge in PAT is image reconstruction with inadequate acoustic signals due to…

Image-guided adaptive lung radiotherapy requires accurate tumor and organs segmentation from during treatment cone-beam CT (CBCT) images. Thoracic CBCTs are hard to segment because of low soft-tissue contrast, imaging artifacts, respiratory…

Image and Video Processing · Electrical Eng. & Systems 2022-03-01 Jue Jiang , Harini Veeraraghavan

Non-invasive imaging of deep blood vessels for mapping hemodynamics remains an open quest in biomedical optical imaging. Although pure optical imaging techniques offer rich optical contrast of blood and have been reported to measure blood…

Medical Physics · Physics 2022-09-20 Yang Zhang , Joshua Olick-Gibson , Anjul Khadria , Lihong V. Wang

In photoacoustic tomography (PAT), a hybrid imaging modality that is based on the acoustic detection of optical absorption from biological tissue exposed to a pulsed laser, a short pulse laser generates an initial pressure proportional to…

Numerical Analysis · Mathematics 2026-03-27 Sunghwan Moon , Anwesa Dey , Souvik Roy

Photoacoustic tomography (PAT) is an emerging imaging modality that aims at measuring the high-contrast optical properties of tissues by means of high-resolution ultrasonic measurements. The interaction between these two types of waves is…

Analysis of PDEs · Mathematics 2021-07-27 Giovanni S. Alberti , Paolo Campodonico , Matteo Santacesaria