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Functional connectomes capture brain interactions via synchronized fluctuations in the functional magnetic resonance imaging signal. If measured during rest, they map the intrinsic functional architecture of the brain. With task-driven…

Neurons and Cognition · Quantitative Biology 2013-04-16 Gaël Varoquaux , R. C. Craddock

In recent years, the lack of reproducibility of research findings has become an important source of concerns in many scientific fields, including functional Magnetic Resonance Imaging (fMRI). The low statistical power often observed in fMRI…

Neurons and Cognition · Quantitative Biology 2024-02-21 Elodie Germani , Xavier Rolland , Pierre Maurel , Camille Maumet

Neurodegenerative diseases are frequently associated with structural changes in the brain. Magnetic Resonance Imaging (MRI) scans can show these variations and therefore be used as a supportive feature for a number of neurodegenerative…

The relation between large-scale brain structure and function is an outstanding open problem in neuroscience. We approach this problem by studying the dynamical regime under which realistic spatio-temporal patterns of brain activity emerge…

Neurons and Cognition · Quantitative Biology 2014-05-27 Ariel Haimovici , Enzo Tagliazucchi , Pablo Balenzuela , Dante R. Chialvo

Brain imaging classification is commonly approached from two perspectives: modeling the full image volume to capture global anatomical context, or constructing ROI-based graphs to encode localized and topological interactions. Although both…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Wei Liang , Lifang He

In recent years there has been explosive growth in the number of neuroimaging studies performed using functional Magnetic Resonance Imaging (fMRI). The field that has grown around the acquisition and analysis of fMRI data is intrinsically…

Methodology · Statistics 2009-06-22 Martin A. Lindquist

Decoding human brain activities via functional magnetic resonance imaging (fMRI) has gained increasing attention in recent years. While encouraging results have been reported in brain states classification tasks, reconstructing the details…

Artificial Intelligence · Computer Science 2017-07-12 Changde Du , Changying Du , Huiguang He

Childhood maltreatment may adversely affect brain development and consequently influence behavioral, emotional, and psychological patterns during adulthood. In this study, we propose an analytical pipeline for modeling the altered…

Neurons and Cognition · Quantitative Biology 2023-11-16 Moo K. Chung , Tahmineh Azizi , Jamie L. Hanson , Andrew L. Alexander , Richard J. Davidson , Seth D. Pollak

Purpose: Functional Magnetic Resonance Imaging (fMRI) data acquired through resting-state studies have been used to obtain information about the spontaneous activations inside the brain. One of the approaches for analysis and interpretation…

Image and Video Processing · Electrical Eng. & Systems 2022-02-24 Harshit Parmar , Brian Nutter , Rodney Long , Sameer Antani , Sunanda Mitra

Current AI frameworks for brain decoding and encoding, typically train and test models within the same datasets. This limits their utility for brain computer interfaces (BCI) or neurofeedback, for which it would be useful to pool…

Developing reliable methods to discriminate different transient brain states that change over time is a key neuroscientific challenge in brain imaging studies. Topological data analysis (TDA), a novel framework based on algebraic topology,…

Neurons and Cognition · Quantitative Biology 2023-12-19 Moo K. Chung , Soumya Das , Hernando Ombao

Background: Functional magnetic resonance imaging (fMRI) provides non-invasive measures of neuronal activity using an endogenous Blood Oxygenation-Level Dependent (BOLD) contrast. This article introduces a nonlinear dimensionality reduction…

Image and Video Processing · Electrical Eng. & Systems 2019-12-09 Gagan Sidhu

Tensor-based morphometry (TBM) aims at showing local differences in brain volumes with respect to a common template. TBM images are smooth but they exhibit (especially in diseased groups) higher values in some brain regions called lateral…

The representations learned by deep neural networks are difficult to interpret in part due to their large parameter space and the complexities introduced by their multi-layer structure. We introduce a method for computing persistent…

Machine Learning · Computer Science 2019-05-31 Thomas Gebhart , Paul Schrater , Alan Hylton

Neuroimaging studies produce gigabytes of spatio-temporal data for a small number of participants and stimuli. Rarely do researchers attempt to model and examine how individual participants vary from each other -- a question that should be…

A central challenge in the computational modeling of neural dynamics is the trade-off between accuracy and simplicity. At the level of individual neurons, nonlinear dynamics are both experimentally established and essential for neuronal…

Little is currently known about the coordination of neural activity over longitudinal time-scales and how these changes relate to behavior. To investigate this issue, we used resting-state fMRI data from a single individual to identify the…

Neurons and Cognition · Quantitative Biology 2017-05-30 James M. Shine , Oluwasanmi Koyejo , Russell A. Poldrack

Functional connectivity (FC) analysis of resting-state fMRI data provides a framework for characterizing brain networks and their association with participant-level covariates. Due to the high dimensionality of neuroimaging data, standard…

Methodology · Statistics 2025-08-18 Wei Zhao , Brian J. Reich , Emily C. Hector

There is increasing evidence on the importance of brain morphology in predicting and classifying mental disorders. However, the vast majority of current shape approaches rely heavily on vertex-wise analysis that may not successfully capture…

Computer Vision and Pattern Recognition · Computer Science 2021-05-26 Yuexuan Wu , Suprateek Kundu , Jennifer S. Stevens , Negar Fani , Anuj Srivastava

We study the persistent homology of both functional data on compact topological spaces and structural data presented as compact metric measure spaces. One of our goals is to define persistent homology so as to capture primarily properties…

Algebraic Topology · Mathematics 2018-11-27 Haibin Hang , Facundo Mémoli , Washington Mio