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Remote photoplethysmography (rPPG) aims to extract non-contact physiological signals from facial videos and has shown great potential. However, existing rPPG approaches struggle to bridge the gap between source and target domains. Recent…

Quantitative Methods · Quantitative Biology 2025-10-03 Shuyang Chu , Jingang Shi , Xu Cheng , Haoyu Chen , Xin Liu , Jian Xu , Guoying Zhao

Quantitatively predicting phenotype variables by the expression changes in a set of candidate genes is of great interest in molecular biology but it is also a challenging task for several reasons. First, the collected biological…

Applications · Statistics 2017-07-21 Emilie Devijver , Mélina Gallopin , Emeline Perthame

Topic models are popular statistical tools for detecting latent semantic topics in a text corpus. They have been utilized in various applications across different fields. However, traditional topic models have some limitations, including…

Computation and Language · Computer Science 2023-10-10 Pritom Saha Akash , Trisha Das , Kevin Chen-Chuan Chang

Large language models (LLMs) suffer from proactive interference (PI): outdated information in the context window disrupts retrieval of current values. This interference degrades retrieval accuracy log-linearly as stale associations…

Artificial Intelligence · Computer Science 2026-03-17 Ying Xie

High-dimensional functional time series (HDFTS) are often characterized by nonlinear trends and high spatial dimensions. Such data poses unique challenges for modeling and forecasting due to the nonlinearity, nonstationarity, and high…

Machine Learning · Statistics 2025-03-28 Haixu Wang , Jiguo Cao

Proteins interact to form complexes to carry out essential biological functions. Computational methods have been developed to predict the structures of protein complexes. However, an important challenge in protein complex structure…

Machine Learning · Computer Science 2022-05-24 Xiao Chen , Alex Morehead , Jian Liu , Jianlin Cheng

Source-Free Domain Adaptation (SFDA) adapts pre-trained models to unlabeled target domains without requiring access to source data. Although state-of-the-art methods leveraging local neighborhood structures show promise for SFDA, they tend…

Computer Vision and Pattern Recognition · Computer Science 2026-03-20 Ying Zheng , Yiyi Zhang , Yi Wang , Lap-Pui Chau

We introduce ProtoSeg, a novel model for interpretable semantic image segmentation, which constructs its predictions using similar patches from the training set. To achieve accuracy comparable to baseline methods, we adapt the mechanism of…

Computer Vision and Pattern Recognition · Computer Science 2025-06-30 Mikołaj Sacha , Dawid Rymarczyk , Łukasz Struski , Jacek Tabor , Bartosz Zieliński

Pocket representations play a vital role in various biomedical applications, such as druggability estimation, ligand affinity prediction, and de novo drug design. While existing geometric features and pretrained representations have…

Machine Learning · Computer Science 2024-03-08 Bowen Gao , Yinjun Jia , Yuanle Mo , Yuyan Ni , Weiying Ma , Zhiming Ma , Yanyan Lan

Approximate Bayesian Computation is widely used in systems biology for inferring parameters in stochastic gene regulatory network models. Its performance hinges critically on the ability to summarize high-dimensional system responses such…

Machine Learning · Statistics 2021-04-13 Mattias Åkesson , Prashant Singh , Fredrik Wrede , Andreas Hellander

Single-cell spatial transcriptomics (ST) offers a unique approach to measuring gene expression profiles and spatial cell locations simultaneously. However, most existing ST methods assume that cells in closer spatial proximity exhibit more…

Genomics · Quantitative Biology 2025-06-10 Xiongtao Xiao , Xiaofeng Chen , Feiyan Jiang , Songming Zhang , Wenming Cao , Cheng Tan , Zhangyang Gao , Zhongshan Li

Accurate flood forecasting remains a challenge for water-resource management, as it demands modeling of local, time-varying runoff drivers (e.g., rainfall-induced peaks, baseflow trends) and complex spatial interactions across a river…

Machine Learning · Computer Science 2025-09-03 Aishwarya Sarkar , Autrin Hakimi , Xiaoqiong Chen , Hai Huang , Chaoqun Lu , Ibrahim Demir , Ali Jannesari

Self-supervised learning has been shown to be very effective in learning useful representations, and yet much of the success is achieved in data types such as images, audio, and text. The success is mainly enabled by taking advantage of…

Machine Learning · Computer Science 2021-10-28 Talip Ucar , Ehsan Hajiramezanali , Lindsay Edwards

Estimating how a treatment affects units individually, known as heterogeneous treatment effect (HTE) estimation, is an essential part of decision-making and policy implementation. The accumulation of large amounts of data in many domains,…

Machine Learning · Computer Science 2022-06-28 Christopher Tran , Elena Zheleva

Motivation: Gene selection has become a common task in most gene expression studies. The objective of such research is often to identify the smallest possible set of genes that can still achieve good predictive performance. The problem of…

Spatio-Temporal predictive Learning is a self-supervised learning paradigm that enables models to identify spatial and temporal patterns by predicting future frames based on past frames. Traditional methods, which use recurrent neural…

Computer Vision and Pattern Recognition · Computer Science 2024-11-18 Andrea Alfarano , Alberto Alfarano , Linda Friso , Andrea Bacciu , Irene Amerini , Fabrizio Silvestri

Despite recent advances in machine learning and explainable AI, a gap remains in personalized preventive healthcare: predictions, interventions, and recommendations should be both understandable and verifiable for all stakeholders in the…

Generalized category discovery (GCD) is a pragmatic but underexplored problem, which requires models to automatically cluster and discover novel categories by leveraging the labeled samples from old classes. The challenge is that unlabeled…

Machine Learning · Computer Science 2025-04-08 Shijie Ma , Fei Zhu , Xu-Yao Zhang , Cheng-Lin Liu

Transfer learning with a small amount of target data is an effective and common approach to adapting a pre-trained model to distribution shifts. In some situations, target data labels may be expensive to obtain, so we may only have access…

Machine Learning · Computer Science 2023-05-26 Annie S. Chen , Yoonho Lee , Amrith Setlur , Sergey Levine , Chelsea Finn

Accurately predicting the survival rate of cancer patients is crucial for aiding clinicians in planning appropriate treatment, reducing cancer-related medical expenses, and significantly enhancing patients' quality of life. Multimodal…

Computer Vision and Pattern Recognition · Computer Science 2024-03-15 Liangrui Pan , Yijun Peng , Yan Li , Xiang Wang , Wenjuan Liu , Liwen Xu , Qingchun Liang , Shaoliang Peng
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