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Prokaryotic gene prediction plays an important role in understanding the biology of organisms and their function with applications in medicine and biotechnology. Although the current gene finders are highly sensitive in finding long genes,…

Genomics · Quantitative Biology 2023-07-21 Tony Tu , Gautham Krishna , Amirali Aghazadeh

The domain discrepancy existed between medical images acquired in different situations renders a major hurdle in deploying pre-trained medical image segmentation models for clinical use. Since it is less possible to distribute training data…

Computer Vision and Pattern Recognition · Computer Science 2022-11-22 Shishuai Hu , Zehui Liao , Yong Xia

Convolutional networks (ConvNets) have achieved promising accuracy for various anatomical segmentation tasks. Despite the success, these methods can be sensitive to data appearance variations. Considering the large variability of scans…

Computer Vision and Pattern Recognition · Computer Science 2021-02-03 Yuan Liang , Weinan Song , Jiawei Yang , Liang Qiu , Kun Wang , Lei He

Tubular structure segmentation (TSS) is important for various applications, such as hemodynamic analysis and route navigation. Despite significant progress in TSS, domain shifts remain a major challenge, leading to performance degradation…

Computer Vision and Pattern Recognition · Computer Science 2025-08-04 Jiale Zhou , Wenhan Wang , Shikun Li , Xiaolei Qu , Xin Guo , Yizhong Liu , Wenzhong Tang , Xun Lin , Yefeng Zheng

Continual Test-Time Adaptation (CTTA) aims to adapt the source model to continually changing unlabeled target domains without access to the source data. Existing methods mainly focus on model-based adaptation in a self-training manner, such…

Computer Vision and Pattern Recognition · Computer Science 2023-02-14 Yulu Gan , Yan Bai , Yihang Lou , Xianzheng Ma , Renrui Zhang , Nian Shi , Lin Luo

We propose an effective lightweight dynamic local and global self-attention network (DLGSANet) to solve image super-resolution. Our method explores the properties of Transformers while having low computational costs. Motivated by the…

Computer Vision and Pattern Recognition · Computer Science 2023-01-06 Xiang Li , Jinshan Pan , Jinhui Tang , Jiangxin Dong

Predicting phenotypes with complex genetic bases based on a small, interpretable set of variant features remains a challenging task. Conventionally, data-driven approaches are utilized for this task, yet the high dimensional nature of…

Machine Learning · Computer Science 2025-04-17 Joseph Lee , Shu Yang , Jae Young Baik , Xiaoxi Liu , Zhen Tan , Dawei Li , Zixuan Wen , Bojian Hou , Duy Duong-Tran , Tianlong Chen , Li Shen

We present ProtoTEx, a novel white-box NLP classification architecture based on prototype networks. ProtoTEx faithfully explains model decisions based on prototype tensors that encode latent clusters of training examples. At inference time,…

Computation and Language · Computer Science 2022-05-24 Anubrata Das , Chitrank Gupta , Venelin Kovatchev , Matthew Lease , Junyi Jessy Li

One main obstacle for the wide use of deep learning in medical and engineering sciences is its interpretability. While neural network models are strong tools for making predictions, they often provide little information about which features…

Machine Learning · Statistics 2021-12-06 Vu Dinh , Lam Si Tung Ho

Prototype-based methods use interpretable representations to address the black-box nature of deep learning models, in contrast to post-hoc explanation methods that only approximate such models. We propose the Neural Prototype Tree…

Computer Vision and Pattern Recognition · Computer Science 2021-04-16 Meike Nauta , Ron van Bree , Christin Seifert

Spatiotemporal predictive learning (STPL) aims to forecast future frames from past observations and is essential across a wide range of applications. Compared with recurrent or hybrid architectures, pure convolutional models offer superior…

Computer Vision and Pattern Recognition · Computer Science 2026-04-23 Xinyong Cai , Changbin Sun , Yong Wang , Hongyu Yang , Yuankai Wu

Data is commonly stored in tabular format. Several fields of research are prone to small imbalanced tabular data. Supervised Machine Learning on such data is often difficult due to class imbalance. Synthetic data generation, i.e.,…

Machine Learning · Computer Science 2022-07-14 Kristian Schultz , Saptarshi Bej , Waldemar Hahn , Markus Wolfien , Prashant Srivastava , Olaf Wolkenhauer

Large Language Models(LLMs) excel in general tasks but struggle in specialized domains like healthcare due to limited domain-specific knowledge.Supervised Fine-Tuning(SFT) data construction for domain adaptation often relies on heuristic…

Machine Learning · Computer Science 2025-09-19 Hongxin Ding , Yue Fang , Runchuan Zhu , Xinke Jiang , Jinyang Zhang , Yongxin Xu , Xu Chu , Junfeng Zhao , Yasha Wang

Generalisation of deep neural networks becomes vulnerable when distribution shifts are encountered between train (source) and test (target) domain data. Few-shot domain adaptation mitigates this issue by adapting deep neural networks…

Computer Vision and Pattern Recognition · Computer Science 2023-08-10 Youssef Dawoud , Gustavo Carneiro , Vasileios Belagiannis

Part-prototype Networks (ProtoPNets) are concept-based classifiers designed to achieve the same performance as black-box models without compromising transparency. ProtoPNets compute predictions based on similarity to class-specific…

Machine Learning · Computer Science 2023-01-24 Andrea Bontempelli , Stefano Teso , Katya Tentori , Fausto Giunchiglia , Andrea Passerini

Tabular data prediction has been employed in medical applications such as patient health risk prediction. However, existing methods usually revolve around the algorithm design while overlooking the significance of data engineering. Medical…

Machine Learning · Computer Science 2024-05-02 Zifeng Wang , Chufan Gao , Cao Xiao , Jimeng Sun

Multimodal molecular representation learning, which jointly models molecular graphs and their textual descriptions, enhances predictive accuracy and interpretability by enabling more robust and reliable predictions of drug toxicity,…

Machine Learning · Computer Science 2025-10-21 Yingxu Wang , Kunyu Zhang , Jiaxin Huang , Nan Yin , Siwei Liu , Eran Segal

Recent applications of deep convolutional neural networks in medical imaging raise concerns about their interpretability. While most explainable deep learning applications use post hoc methods (such as GradCAM) to generate feature…

Computer Vision and Pattern Recognition · Computer Science 2023-04-17 Yuanyuan Wei , Roger Tam , Xiaoying Tang

Test Time Adaptation (TTA) addresses the problem of distribution shift by adapting a pretrained model to a new domain during inference. When faced with challenging shifts, most methods collapse and perform worse than the original pretrained…

Machine Learning · Computer Science 2025-02-25 Sabyasachi Sahoo , Mostafa ElAraby , Jonas Ngnawe , Yann Pequignot , Frederic Precioso , Christian Gagne

In the arena of language model fine-tuning, the traditional approaches, such as Domain-Adaptive Pretraining (DAPT) and Task-Adaptive Pretraining (TAPT), although effective, but computational intensive. This research introduces a novel…

Computation and Language · Computer Science 2024-05-10 Keyu Chen , Yuan Pang , Zi Yang