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Quantitative magnetic resonance imaging (qMRI) requires multi-phase acqui-sition, often relying on reduced data sampling and reconstruction algorithms to accelerate scans, which inherently poses an ill-posed inverse problem. While many…
In this article, we propose a novel regularization method for a class of nonlinear inverse problems that is inspired by an application in quantitative magnetic resonance imaging (qMRI). The latter is a special instance of a general…
This paper proposes a novel self-supervised learning method, RELAX-MORE, for quantitative MRI (qMRI) reconstruction. The proposed method uses an optimization algorithm to unroll a model-based qMRI reconstruction into a deep learning…
In the last years, the design of image reconstruction methods in the field of quantitative Magnetic Resonance Imaging (qMRI) has experienced a paradigm shift. Often, when dealing with (quantitative) MR image reconstruction problems, one is…
Quantitative MRI (qMRI) methods allow reducing the subjectivity of clinical MRI by providing numerical values on which diagnostic assessment or predictions of tissue properties can be based. However, qMRI measurements typically take more…
Magnetic particle imaging (MPI) offers unparalleled contrast and resolution for tracing magnetic nanoparticles. A common imaging procedure calibrates a system matrix (SM) that is used to reconstruct data from subsequent scans. The ill-posed…
In the field of quantitative imaging, the image information at a pixel or voxel in an underlying domain entails crucial information about the imaged matter. This is particularly important in medical imaging applications, such as…
Quantitative Magnetic Resonance Imaging (qMRI) provides researchers insight into pathological and physiological alterations of living tissue, with the help of which researchers hope to predict (local) therapeutic efficacy early and…
Purpose: To develop a self-supervised scan-specific deep learning framework for reconstructing accelerated multiparametric quantitative MRI (qMRI). Methods: We propose REFINE-MORE (REference-Free Implicit NEural representation with MOdel…
Quantitative magnetic resonance imaging (qMRI) allows images to be compared across sites and time points, which is particularly important for assessing long-term conditions or for longitudinal studies. The multiparametric mapping (MPM)…
We propose a model-based deep learning architecture for the reconstruction of highly accelerated diffusion magnetic resonance imaging (MRI) that enables high resolution imaging. The proposed reconstruction jointly recovers all the diffusion…
Quantitative susceptibility mapping (QSM) utilizes MRI signal phase to infer estimates of local tissue magnetism (magnetic susceptibility), which has been shown useful to provide novel image contrast and as biomarkers of abnormal tissue.…
Quantitative magnetic resonance imaging (qMRI) provides tissue-specific parameters vital for clinical diagnosis. Although simultaneous multi-parametric qMRI (MP-qMRI) technologies enhance imaging efficiency, robustly reconstructing qMRI…
Magnetic resonance imaging (MRI) offers superior soft tissue contrast and is widely used in biomedicine. However, conventional MRI is not quantitative, which presents a bottleneck in image analysis and digital healthcare. Typically,…
Objective: We propose a method for the reconstruction of parameter-maps in Quantitative Magnetic Resonance Imaging (QMRI). Methods: Because different quantitative parameter-maps differ from each other in terms of local features, we propose…
Magnetic Resonance Fingerprinting (MRF) and other highly accelerated transient-state parameter mapping techniques enable simultaneous quantification of multiple tissue properties, but often suffer from aliasing artifacts due to compressed…
Recently, Magnetic Resonance Fingerprinting (MRF) was proposed as a quantitative imaging technique for the simultaneous acquisition of tissue parameters such as relaxation times $T_1$ and $T_2$. Although the acquisition is highly…
Quantitative Susceptibility Mapping (QSM) can estimate the underlying tissue magnetic susceptibility and reveal pathology. Current deep-learning-based approaches to solve the QSM inverse problem are restricted on fixed image resolution.…
Acquisition of Magnetic Resonance Imaging (MRI) scans can be accelerated by under-sampling in k-space (i.e., the Fourier domain). In this paper, we consider the problem of optimizing the sub-sampling pattern in a data-driven fashion. Since…
This dissertation is devoted to provide advanced nonconvex nonsmooth variational models of (Magnetic Resonance Image) MRI reconstruction, efficient learnable image reconstruction algorithms and parameter training algorithms that improve the…