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Given a family of feasible subsets of a ground set, the packing problem is to find a largest subfamily of pairwise disjoint family members. Non-approximability renders heuristics attractive viable options, while efficient methods with…

Discrete Mathematics · Computer Science 2015-09-29 Giovanni Rossi

The exploration of vast genotype spaces poses fundamental challenges for evolving populations. As the number of genotypes encoding viable phenotypes grows exponentially with genome length, populations can only explore a tiny fraction of…

Populations and Evolution · Quantitative Biology 2026-01-21 Susanna Manrubia , Luis F. Seoane , José A. Cuesta

Many researchers have studied symmetry properties of various Boolean functions. A class of Boolean functions, called nested canalyzing functions (NCFs), has been used to model certain biological phenomena. We identify some interesting…

Discrete Mathematics · Computer Science 2023-06-22 Daniel J. Rosenkrantz , Madhav V. Marathe , S. S. Ravi , Richard E. Stearns

In several combinatorial optimization problems arising in cryptography and design theory, the admissible solutions must often satisfy a balancedness constraint, such as being represented by bitstrings with a fixed number of ones. For this…

Neural and Evolutionary Computing · Computer Science 2019-11-19 Luca Manzoni , Luca Mariot , Eva Tuba

In this paper we consider a problem of searching a space of predictive models for a given training data set. We propose an iterative procedure for deriving a sequence of improving models and a corresponding sequence of sets of non-linear…

Machine Learning · Computer Science 2014-02-18 Michael Tetelman

We develop a Bayesian graphical modeling framework for functional data for correlated multivariate random variables observed over a continuous domain. Our method leads to graphical Markov models for functional data which allows the graphs…

In recent years, manifold methods have moved into focus as tools for dimension reduction. Assuming that the high-dimensional data actually lie on or close to a low-dimensional nonlinear manifold, these methods have shown convincing results…

Machine Learning · Statistics 2020-12-23 Moritz Herrmann , Fabian Scheipl

Function approximation from input and output data pairs constitutes a fundamental problem in supervised learning. Deep neural networks are currently the most popular method for learning to mimic the input-output relationship of a general…

Machine Learning · Computer Science 2019-12-09 Nikos Kargas , Nicholas D. Sidiropoulos

Mass spectrometry proteomics, characterized by spiky, spatially heterogeneous functional data, can be used to identify potential cancer biomarkers. Existing mass spectrometry analyses utilize mean regression to detect spectral regions that…

Methodology · Statistics 2020-07-03 Yusha Liu , Meng Li , Jeffrey S. Morris

Many constraint satisfaction and optimisation problems can be solved effectively by encoding them as instances of the Boolean Satisfiability problem (SAT). However, even the simplest types of constraints have many encodings in the…

Artificial Intelligence · Computer Science 2023-11-09 Felix Ulrich-Oltean , Peter Nightingale , James Alfred Walker

We develop efficient algorithms for optimizing piecewise smooth (PWS) functions where the underlying partition of the domain into smooth pieces is \emph{unknown}. For PWS functions satisfying a quadratic growth (QG) condition, we propose a…

Optimization and Control · Mathematics 2025-07-28 Zhe Zhang , Suvrit Sra

This paper investigates the existence of solutions for a class of nonlinear higher-order dynamic equations subject to mixed boundary conditions. We consider boundary value problems in which the nonlinear reaction functions satisfy…

Classical Analysis and ODEs · Mathematics 2025-06-11 Shalmali Bandyopadhyay , Svetlin G. Georgiev

We propose the introduction of nonlinear operation into the feature generation process in convolutional neural networks. This nonlinearity can be implemented in various ways. First we discuss the use of nonlinearities in the process of data…

Machine Learning · Computer Science 2019-05-30 Gavneet Singh Chadha , Andreas Schwung

Accurate models are essential for design, performance prediction, control, and diagnostics in complex engineering systems. Physics-based models excel during the design phase but often become outdated during system deployment due to changing…

Machine Learning · Computer Science 2025-01-22 Zihan Liu , Prashant N. Kambali , C. Nataraj

The search for Boolean functions that can withstand the main crypyographic attacks is essential. In 2008, Carlet and Feng studied a class of functions which have optimal cryptographic properties with the exception of nonlinearity for which…

Information Theory · Computer Science 2020-03-30 François Rodier

Signed networks, characterized by edges labeled as either positive or negative, offer nuanced insights into interaction dynamics beyond the capabilities of unsigned graphs. Central to this is the task of identifying the maximum balanced…

Social and Information Networks · Computer Science 2024-06-18 Jingbang Chen , Qiuyang Mang , Hangrui Zhou , Richard Peng , Yu Gao , Chenhao Ma

Motivation. Protein design aims to identify sequences compatible with a given protein fold but incompatible to any alternative folds. To select the correct sequences and to guide the search process, a design scoring function is critically…

Biomolecules · Quantitative Biology 2007-05-23 Changyu Hu , Xiang Li , Jie Liang

Fitness landscapes are a useful concept to study the dynamics of meta-heuristics. In the last two decades, they have been applied with success to estimate the optimization power of several types of evolutionary algorithms, including genetic…

Neural and Evolutionary Computing · Computer Science 2020-01-31 Nuno M. Rodrigues , Sara Silva , Leonardo Vanneschi

Potential functions are critical for computational studies of protein structure prediction, folding, and sequence design. A class of widely used potentials for coarse grained models of proteins are contact potentials in the form of weighted…

Soft Condensed Matter · Physics 2007-05-23 Changyu Hu , Xiang Li , Jie Liang

In this paper we compute the Fourier spectra of some recently discovered binomial APN functions. One consequence of this is the determination of the nonlinearity of the functions, which measures their resistance to linear cryptanalysis.…

Discrete Mathematics · Computer Science 2008-12-18 Carl Bracken , Eimear Byrne , Nadya Markin , Gary McGuire