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Many biological processes occur on time scales longer than those accessible to molecular dynamics simulations. Identifying collective variables (CVs) and introducing an external potential to accelerate them is a popular approach to address…

Computational Physics · Physics 2024-10-24 Enrico Trizio , Andrea Rizzi , Pablo M. Piaggi , Michele Invernizzi , Luigi Bonati

Statistical models and methods for determinantal point processes (DPPs) seem largely unexplored. We demonstrate that DPPs provide useful models for the description of spatial point pattern datasets where nearby points repel each other. Such…

Statistics Theory · Mathematics 2016-04-28 Frédéric Lavancier , Jesper Møller , Ege Rubak

The paper discusses multivariate self- and cross-exciting processes. We define a class of multivariate point processes via their corresponding stochastic intensity processes that are driven by stochastic jumps. Essentially, there is a jump…

Probability · Mathematics 2021-08-24 Heidar Eyjolfsson , Dag Tjøstheim

Enhanced sampling algorithms have emerged as powerful methods to extend the utility of molecular dynamics simulations and allow the sampling of larger portions of the configuration space of complex systems in a given amount of simulation…

Statistical Mechanics · Physics 2022-12-19 Jérôme Hénin , Tony Lelièvre , Michael R. Shirts , Omar Valsson , Lucie Delemotte

The use of stochastic models, in effect piecewise deterministic Markov processes (PDMP), has become increasingly popular especially for the modeling of chemical reactions and cell biophysics. Yet, exact simulation methods, for the…

Numerical Analysis · Mathematics 2015-04-28 Romain Veltz

Joint models of longitudinal and event-time data have been extensively studied and applied in many different fields. Estimation of joint models is challenging, most present procedures are computational expensive and have a strict…

Methodology · Statistics 2018-09-05 Yanqiao Zheng , Xiaobing Zhao , Xiaoqi Zhang

We introduce ACEpotentials.jl, a Julia-language software package that constructs interatomic potentials from quantum mechanical reference data using the Atomic Cluster Expansion (Drautz, 2019). As the latter provides a complete description…

Direct numerical simulations (DNS) are accurate but computationally expensive for predicting materials evolution across timescales, due to the complexity of the underlying evolution equations, the nature of multiscale spatio-temporal…

Machine Learning · Computer Science 2023-12-12 Vivek Oommen , Khemraj Shukla , Saaketh Desai , Remi Dingreville , George Em Karniadakis

Massively parallel molecular simulations require pseudorandom number streams that are provably non-overlapping and reproducible across thousands of compute units in parallel computing environments. In the widely used LAMMPS package, the…

Mathematical Software · Computer Science 2025-12-02 Hiroshi Haramoto , Kosuke Suzuki

We introduce the `nhppp' package for simulating events from one-dimensional non-homogeneous Poisson point processes (NHPPPs) in R fast and with a small memory footprint. We developed it to facilitate the sampling of event times in discrete…

Computation · Statistics 2024-05-30 Thomas A. Trikalinos , Yuliia Sereda

The simulation of high-energy physics collision events is a key element for data analysis at present and future particle accelerators. The comparison of simulation predictions to data allows looking for rare deviations that can be due to…

High Energy Physics - Experiment · Physics 2024-07-16 Francesco Vaselli , Filippo Cattafesta , Patrick Asenov , Andrea Rizzi

Gaussian processes are a class of flexible nonparametric Bayesian tools that are widely used across the sciences, and in industry, to model complex data sources. Key to applying Gaussian process models is the availability of well-developed…

Computation · Statistics 2019-07-02 Jamie Fairbrother , Christopher Nemeth , Maxime Rischard , Johanni Brea , Thomas Pinder

Multiphase turbulent flow phenomena are observed not only in industrial devices but also in environmental flows, and direct numerical simulation (DNS) plays a key role in their investigation. Many numerical models have been developed;…

Fluid Dynamics · Physics 2026-04-14 Taketo Tominaga , Ryo Onishi

In the nonlinear timeseries analysis literature, countless quantities have been presented as new ``entropy'' or ``complexity'' measures, often with similar roles. The ever-increasing pool of such measures makes creating a sustainable and…

Software Engineering · Computer Science 2025-09-25 George Datseris , Kristian Agasøster Haaga

This work develops novel error expansions with computable leading order terms for the global weak error in the tau-leap discretization of pure jump processes arising in kinetic Monte Carlo models. Accurate computable a posteriori error…

Numerical Analysis · Mathematics 2011-10-21 Jesper Karlsson , Raul Tempone

In real-world scenario, many phenomena produce a collection of events that occur in continuous time. Point Processes provide a natural mathematical framework for modeling these sequences of events. In this survey, we investigate…

MomentClosure.jl is a Julia package providing automated derivation of the time-evolution equations of the moments of molecule numbers for virtually any chemical reaction network using a wide range of moment closure approximations. It…

Molecular Networks · Quantitative Biology 2021-05-13 Augustinas Sukys , Ramon Grima

Markov jump processes are continuous-time stochastic processes which describe dynamical systems evolving in discrete state spaces. These processes find wide application in the natural sciences and machine learning, but their inference is…

Machine Learning · Computer Science 2025-03-05 David Berghaus , Kostadin Cvejoski , Patrick Seifner , Cesar Ojeda , Ramses J. Sanchez

Large Language Models (LLMs) are increasingly embedded in applications, and people can shape model behavior by editing prompt instructions. Yet encoding subtle, domain-specific policies into prompts is challenging. Although this process…

Human-Computer Interaction · Computer Science 2026-03-26 Minjae Lee , Minsuk Kahng

In this article, we present the potential benefits of incorporating jumps into the dynamics of digital memcomputing machines (DMMs), which have been developed to address complex optimization problems. We illustrate the potential speed…

Emerging Technologies · Computer Science 2026-02-03 Yuriy V. Pershin